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Drug ReportsPeramivir
Rapivab, Alpivab(peramivir)
Alpivab, Rapivab (peramivir) is a small molecule pharmaceutical. Peramivir was first approved as Rapivab on 2014-12-19. It is used to treat human influenza in the USA. It has been approved in Europe to treat human influenza.
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FDA approval date
EMA approval date
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Study first post date
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
respiratory tract diseasesD012140
Trade Name
FDA
EMA
Rapivab
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Peramivir
Tradename
Company
Number
Date
Products
RAPIVABBioCryst PharmaceuticalsN-206426 RX2014-12-19
1 products, RLD, RS
Labels
FDA
EMA
Brand Name
Status
Last Update
rapivabNew Drug Application2024-06-18
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
human influenzaEFO_0007328D007251J11.1
Agency Specific
FDA
EMA
No data
Patent Expiration
Patent
Expires
Flag
FDA Information
Peramivir, Rapivab, Biocryst
87789972027-05-07U-1627, U-2622, U-3069
103910752027-02-12U-2622, U-3069
ATC Codes
J: Antiinfectives for systemic use
J05: Antivirals for systemic use
J05A: Direct acting antivirals
J05AH: Neuraminidase inhibitors, direct acting antivirals
J05AH03: Peramivir
HCPCS
Code
Description
J2547
Injection, peramivir, 1 mg
Clinical
No data
Drug
General
Drug common namePeramivir
INNperamivir
Description
Peramivir (trade name Rapivab) is an antiviral drug developed by BioCryst Pharmaceuticals for the treatment of influenza. Peramivir is a neuraminidase inhibitor, acting as a transition-state analogue inhibitor of influenza neuraminidase and thereby preventing new viruses from emerging from infected cells. It is approved for intravenous administration.
Classification
Small molecule
Drug classantivirals: neuraminidase inhibitors
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
CCC(CC)[C@H](NC(C)=O)[C@@H]1[C@H](O)[C@@H](C(=O)O)C[C@H]1NC(=N)N
Identifiers
PDB
CAS-ID330600-85-6
RxCUI
ChEMBL IDCHEMBL139367
ChEBI ID85202
PubChem CID151164
DrugBankDB06614
UNII ID9ZS94HQO3B (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
No data
Trends
No data
Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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