Therapeutic Area | MeSH |
---|---|
neoplasms | D009369 |
respiratory tract diseases | D012140 |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
PEMETREXED DISODIUM | Accord Healthcare | N-214408 RX | 2022-07-19 | 4 products, RLD, RS |
PEMETREXED DISODIUM | Hospira | N-214218 RX | 2022-06-22 | 3 products, RLD, RS |
ALIMTA | Eli Lilly | N-021462 RX | 2004-02-04 | 2 products, RLD, RS |
PEMETREXED DISODIUM | Sandoz | N-214657 RX | 2022-05-26 | 3 products, RLD, RS |
PEMETREXED | Shilpa Medicare | N-215179 RX | 2023-05-22 | 3 products, RLD, RS |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
PEMETREXED | Allergan | N-208419 RX | 2020-08-21 | 3 products, RLD, RS |
PEMFEXY | Eagle Pharmaceuticals | N-209472 RX | 2020-02-08 | 1 products, RLD, RS |
Brand Name | Status | Last Update |
---|---|---|
alimta | New Drug Application | 2023-05-19 |
axtle | New Drug Application | 2024-12-27 |
pemetrexed | New Drug Application | 2024-11-28 |
pemetrexed dipotassium | New Drug Application | 2025-02-05 |
pemetrexed disodium | ANDA | 2022-11-15 |
pemetrexed pemetrexed | ANDA | 2025-04-01 |
pemfexy | New Drug Application | 2023-05-15 |
pemrydi rtu | New Drug Application | 2024-11-11 |
Indication | Ontology | MeSH | ICD-10 |
---|---|---|---|
non-small-cell lung carcinoma | — | D002289 | — |
mesothelial neoplasms | — | D018301 | — |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Non-small-cell lung carcinoma | D002289 | — | — | 12 | 59 | 18 | 2 | 2 | 85 |
Lung neoplasms | D008175 | — | C34.90 | 11 | 60 | 17 | 2 | 3 | 84 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Neoplasms | D009369 | — | C80 | 12 | 11 | 1 | — | — | 21 |
Neoplasm metastasis | D009362 | EFO_0009708 | — | 3 | 4 | 2 | — | — | 9 |
Mesothelioma | D008654 | — | C45 | 2 | 6 | 1 | — | 1 | 9 |
Head and neck neoplasms | D006258 | — | — | 2 | 5 | 1 | — | — | 8 |
Small cell lung carcinoma | D055752 | — | — | 2 | 6 | 1 | — | — | 8 |
Malignant mesothelioma | D000086002 | — | — | 2 | 5 | 1 | — | 1 | 8 |
Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 1 | 4 | 1 | — | — | 5 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Breast neoplasms | D001943 | EFO_0003869 | C50 | 5 | 15 | — | — | — | 17 |
Colorectal neoplasms | D015179 | — | — | 5 | 5 | — | — | — | 8 |
Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 3 | 7 | — | — | — | 8 |
Carcinoma | D002277 | — | C80.0 | — | 6 | — | — | — | 6 |
Stomach neoplasms | D013274 | EFO_0003897 | C16 | 1 | 4 | — | — | — | 4 |
Peritoneal neoplasms | D010534 | — | — | 1 | 3 | — | — | — | 3 |
Small cell carcinoma | D018288 | — | — | 1 | 3 | — | — | — | 3 |
Endometrial neoplasms | D016889 | EFO_0004230 | — | 2 | 2 | — | — | — | 3 |
Uterine neoplasms | D014594 | EFO_0003859 | C55 | — | 3 | — | — | — | 3 |
Urologic neoplasms | D014571 | — | C64-C68 | 1 | 3 | — | — | — | 3 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Lymphoma | D008223 | — | C85.9 | 2 | — | — | — | — | 2 |
Glioma | D005910 | EFO_0000520 | — | 1 | — | — | — | — | 1 |
Chordoma | D002817 | EFO_0000334 | — | 1 | — | — | — | — | 1 |
Squamous cell carcinoma | D002294 | — | — | 1 | — | — | — | — | 1 |
Squamous cell neoplasms | D018307 | — | — | 1 | — | — | — | — | 1 |
Non-hodgkin lymphoma | D008228 | — | C85.9 | 1 | — | — | — | — | 1 |
Central nervous system neoplasms | D016543 | — | — | 1 | — | — | — | — | 1 |
Mycoses | D009181 | — | B35-B49 | 1 | — | — | — | — | 1 |
Sezary syndrome | D012751 | — | C84.1 | 1 | — | — | — | — | 1 |
Mycosis fungoides | D009182 | — | C84.0 | 1 | — | — | — | — | 1 |
Drug common name | Pemetrexed |
INN | pemetrexed |
Description | Pemetrexed, sold under the brand name Alimta among others, is a chemotherapy medication for the treatment of pleural mesothelioma and non-small cell lung cancer (NSCLC)..
|
Classification | Small molecule |
Drug class | antineoplastic thymidylate synthetase inhibitors |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | Nc1nc2[nH]cc(CCc3ccc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)cc3)c2c(=O)[nH]1 |
PDB | — |
CAS-ID | 137281-23-3 |
RxCUI | — |
ChEMBL ID | CHEMBL225072 |
ChEBI ID | 63616 |
PubChem CID | 446556 |
DrugBank | DB00642 |
UNII ID | 04Q9AIZ7NO (ChemIDplus, GSRS) |