Brand Name | Status | Last Update |
---|---|---|
lyophilized pegaspargase | Export only | 2020-08-03 |
oncaspar | Biologic Licensing Application | 2024-10-07 |
Indication | Ontology | MeSH | ICD-10 |
---|---|---|---|
non-hodgkin lymphoma | — | D008228 | C85.9 |
precursor cell lymphoblastic leukemia-lymphoma | — | D054198 | C91.0 |
b-cell chronic lymphocytic leukemia | — | D015451 | C91.1 |
blast crisis | — | D001752 | — |
Expiration | Code | ||
---|---|---|---|
pegaspargase, Oncaspar, Servier Pharmaceuticals LLC | |||
2101-02-01 | Orphan excl. |
Code | Description |
---|---|
J9266 | Injection, pegaspargase, per single dose vial |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Myelodysplastic syndromes | D009190 | — | D46 | 1 | — | — | — | — | 1 |
Myeloid leukemia acute | D015470 | — | C92.0 | 1 | — | — | — | — | 1 |
Hematologic neoplasms | D019337 | — | — | 1 | — | — | — | — | 1 |
Recurrence | D012008 | — | — | 1 | — | — | — | — | 1 |
Non-hodgkin lymphoma | D008228 | — | C85.9 | 1 | — | — | — | — | 1 |
Preleukemia | D011289 | — | — | 1 | — | — | — | — | 1 |
Acute disease | D000208 | — | — | 1 | — | — | — | — | 1 |
Syndrome | D013577 | — | — | 1 | — | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Residual neoplasm | D018365 | — | — | — | — | — | — | 1 | 1 |
Eye abnormalities | D005124 | — | Q15.9 | — | — | — | — | 1 | 1 |
Drug common name | Pegaspargase |
INN | pegaspargase |
Description | Pegaspargase, sold under the brand name Oncaspar, is a medication used in the treatment of acute lymphoblastic leukemia (ALL). Often it is used together with anthracycline, vincristine, and corticosteroids (for example prednisone and dexamethasone). Pegaspargase can be administered either via an intravenous infusion or a intramuscular injection.
|
Classification | Enzyme |
Drug class | enzymes; PEGylated compounds, covalent attachment of macrogol (polyethylene glycol) polymer |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | — |
PDB | — |
CAS-ID | — |
RxCUI | — |
ChEMBL ID | CHEMBL2108546 |
ChEBI ID | — |
PubChem CID | — |
DrugBank | DB00059 |
UNII ID | 7D96IR0PPM (ChemIDplus, GSRS) |