Therapeutic Area | MeSH |
---|---|
neoplasms | D009369 |
urogenital diseases | D000091642 |
Indication | Ontology | MeSH | ICD-10 |
---|---|---|---|
renal cell carcinoma | EFO_0000376 | D002292 | — |
soft tissue neoplasms | — | D012983 | — |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Renal cell carcinoma | D002292 | EFO_0000376 | — | 2 | 6 | 3 | 2 | 2 | 15 |
Carcinoma | D002277 | — | C80.0 | 2 | 6 | 3 | 2 | 2 | 15 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Neoplasms | D009369 | — | C80 | 6 | 3 | 1 | — | — | 8 |
Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 1 | 3 | 1 | — | — | 4 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Sarcoma | D012509 | — | — | 3 | 5 | — | — | — | 6 |
Ovarian epithelial carcinoma | D000077216 | — | — | 1 | 3 | — | — | — | 3 |
Kidney neoplasms | D007680 | EFO_0003865 | C64 | 1 | 2 | — | — | — | 3 |
Hemangiosarcoma | D006394 | — | — | — | 2 | — | — | — | 2 |
Leiomyosarcoma | D007890 | — | — | — | 2 | — | — | — | 2 |
Osteosarcoma | D012516 | — | — | — | 2 | — | — | — | 2 |
Liposarcoma | D008080 | — | — | — | 2 | — | — | — | 2 |
Melanoma | D008545 | — | — | — | 1 | — | — | — | 1 |
Gastrointestinal stromal tumors | D046152 | EFO_0000505 | C49.A | — | 1 | — | — | — | 1 |
Carcinosarcoma | D002296 | — | — | — | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Squamous cell carcinoma of head and neck | D000077195 | — | — | 1 | — | — | — | — | 1 |
Squamous cell carcinoma | D002294 | — | — | 1 | — | — | — | — | 1 |
Neoplasm metastasis | D009362 | EFO_0009708 | — | 1 | — | — | — | — | 1 |
Thyroid neoplasms | D013964 | EFO_0003841 | — | 1 | — | — | — | — | 1 |
Cholangiocarcinoma | D018281 | — | C22.1 | 1 | — | — | — | — | 1 |
Thyroid diseases | D013959 | — | E00-E07 | 1 | — | — | — | — | 1 |
Drug common name | Pazopanib |
INN | pazopanib |
Description | Pazopanib hydrochloride is a hydrochloride salt prepared from equimolar amounts of pazopanib and hydrochloric acid. Used for treatment of kidney cancer. It has a role as an antineoplastic agent, a vascular endothelial growth factor receptor antagonist, a tyrosine kinase inhibitor and an angiogenesis modulating agent. It contains a pazopanib(1+). |
Classification | Small molecule |
Drug class | angiogenesis inhibitors |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | Cc1ccc(Nc2nccc(N(C)c3ccc4c(C)n(C)nc4c3)n2)cc1S(N)(=O)=O |
PDB | — |
CAS-ID | 444731-52-6 |
RxCUI | — |
ChEMBL ID | CHEMBL477772 |
ChEBI ID | 71219 |
PubChem CID | 11525740 |
DrugBank | DB06589 |
UNII ID | 7RN5DR86CK (ChemIDplus, GSRS) |