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Drug ReportsParomomycin
Paromomycin
Paromomycin (paromomycin) is a small molecule pharmaceutical. Paromomycin was first approved as Humatin on 1982-01-01. It is used to treat amebiasis, cryptosporidiosis, and protozoan infections in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
digestive system diseasesD004066
animal diseasesD000820
Trade Name
FDA
EMA
Paromomycin (discontinued: Humatin, Paromomycin)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
Brand Name
Status
Last Update
care science essential first aidC2002632024-08-29
care science osha first aidC2002632024-02-05
emergency preparednessOTC monograph final2010-06-02
good neighbor pharmacy emergency preparedness and first aid contains 167 piecesOTC monograph final2010-06-11
humatinANDA2023-01-10
madecassolunapproved drug other2019-11-08
paromomycin sulfateANDA2017-11-07
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
cryptosporidiosisD003457A07.2
protozoan infectionsD011528B50-B64
amebiasisEFO_0007144D000562A06
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
A: Alimentary tract and metabolism drugs
A07: Antidiarrheals, intestinal antiinflammatory/antiinfective agents
A07A: Intestinal antiinfectives
A07AA: Antibiotics, intestinal
A07AA06: Paromomycin
HCPCS
No data
Clinical
No data
Drug
General
Drug common nameParomomycin
INNparomomycin
Description
Paromomycin sulfate is an aminoglycoside sulfate salt resulting from the treatment of paromomycin with sulfuric acid. A broad-spectrum antibiotic, it is used for the treatment of acute and chronic intestinal protozoal infections, but is not effective for extraintestinal protozoal infections. It is also used as a therapeutic against visceral leishmaniasis. It has a role as an antibacterial drug, an antiprotozoal drug, an anthelminthic drug and an antiparasitic agent. It is functionally related to a paromomycin.
Classification
Small molecule
Drug classantibiotics (Streptomyces strain)
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
NC[C@@H]1O[C@H](O[C@@H]2[C@@H](CO)O[C@@H](O[C@@H]3[C@@H](O)[C@H](N)C[C@H](N)[C@H]3O[C@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3N)[C@@H]2O)[C@H](N)[C@@H](O)[C@@H]1O
Identifiers
PDB
CAS-ID7542-37-2
RxCUI
ChEMBL IDCHEMBL370143
ChEBI ID7934
PubChem CID441375
DrugBankDB01421
UNII ID61JJC8N5ZK (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
Revenue by drug
$
£
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Estimated US medical usage
Paromomycin
Total medical expenditures per year (USD, in millions)
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Trends
No data
Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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