Pancreatin
Pancreatin is an unknown pharmaceutical. It is currently being investigated in clinical studies.
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219 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Exocrine pancreatic insufficiency | D010188 | — | K86.81 | 3 | 5 | 17 | 14 | 6 | 43 |
| Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | 6 | 2 | 1 | 2 | 29 | 40 |
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 7 | 14 | 2 | 3 | 16 | 39 |
| Fibrosis | D005355 | — | — | — | 2 | 12 | 6 | 8 | 28 |
| Cystic fibrosis | D003550 | EFO_0000390 | E84 | — | 2 | 12 | 7 | 7 | 28 |
| Pancreatitis | D010195 | EFO_0000278 | K85 | 6 | 3 | 4 | 6 | 7 | 25 |
| Chronic pancreatitis | D050500 | EFO_0000342 | K86.1 | 4 | 3 | 4 | 5 | 4 | 19 |
| Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | — | — | — | 1 | 6 | 7 |
| Pancreatic diseases | D010182 | — | K86.9 | — | — | — | 1 | 5 | 6 |
| Steatorrhea | D045602 | — | — | 1 | 1 | 3 | 1 | — | 6 |
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Type 1 diabetes mellitus | D003922 | EFO_0001359 | E10 | 9 | 9 | 7 | — | 58 | 79 |
| Malnutrition | D044342 | EFO_0008572 | E40-E46 | — | 1 | 1 | — | 3 | 4 |
| Chronic kidney failure | D007676 | EFO_0003884 | N18.6 | — | — | 1 | — | 2 | 3 |
| Malabsorption syndromes | D008286 | EFO_0009554 | K90 | — | 2 | 1 | — | — | 3 |
| Pancreatectomy | D010180 | EFO_0002581 | — | — | — | 3 | — | — | 3 |
| Diabetic nephropathies | D003928 | EFO_0000401 | — | — | — | 1 | — | — | 1 |
| Sepsis | D018805 | EFO_0001420 | A41.9 | — | 1 | 1 | — | — | 1 |
| Child nutrition disorders | D015362 | — | — | — | 1 | 1 | — | — | 1 |
| Renal insufficiency | D051437 | — | N19 | — | — | 1 | — | — | 1 |
| Eructation | D004884 | — | R14.2 | — | — | 1 | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pancreatic cyst | D010181 | — | K86.2 | 1 | — | — | — | 4 | 5 |
| Hypoglycemia | D007003 | — | E16.2 | 1 | — | — | — | 3 | 4 |
| Cysts | D003560 | — | — | 1 | — | — | — | 2 | 3 |
| Abdominal pain | D015746 | EFO_0003766 | R10.9 | 1 | — | — | — | 1 | 2 |
| Graft pancreatitis | D055589 | — | — | 1 | — | — | — | — | 1 |
| Pancreaticojejunostomy | D010193 | — | — | 1 | — | — | — | — | 1 |
| Renal cell carcinoma | D002292 | EFO_0000376 | — | 1 | — | — | — | — | 1 |
| Hepatocellular carcinoma | D006528 | — | C22.0 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hyperglycemia | D006943 | — | R73.9 | — | — | — | — | 3 | 3 |
| Gastrointestinal diseases | D005767 | — | — | — | — | — | — | 3 | 3 |
| Digestive system diseases | D004066 | EFO_0000405 | K92.9 | — | — | — | — | 3 | 3 |
| Pancreatic fistula | D010185 | — | — | — | — | — | — | 2 | 2 |
| Fistula | D005402 | — | — | — | — | — | — | 2 | 2 |
| Cholangiocarcinoma | D018281 | — | C22.1 | — | — | — | — | 2 | 2 |
| Obesity | D009765 | EFO_0001073 | E66.9 | — | — | — | — | 2 | 2 |
| Lung neoplasms | D008175 | — | C34.90 | — | — | — | — | 1 | 1 |
| Kidney transplantation | D016030 | — | — | — | — | — | — | 1 | 1 |
| Organ transplantation | D016377 | — | — | — | — | — | — | 1 | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Pancreatin |
| INN | — |
| Description | Pancreatic enzymes, also known as pancreases or pancrelipase and pancreatin, are commercial mixtures of amylase, lipase, protease and lactase. They are used to treat malabsorption syndrome due to certain pancreatic problems. These pancreatic problems may be due to cystic fibrosis, surgical removal of the pancreas, long term pancreatitis, pancreatic cancer, or MODY 5, among others. The preparation is taken by mouth.
|
| Classification | Unknown |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL2108073 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | DB00085 |
| UNII ID | — |
Target
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Safety
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Adverse Events
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