POZANICLINE
Pozanicline is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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Clinical
Clinical Trials
11 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hyperkinesis | D006948 | HP_0000752 | — | — | 7 | — | — | — | 7 |
| Attention deficit disorder with hyperactivity | D001289 | EFO_0003888 | F90 | — | 7 | — | — | — | 7 |
| Alzheimer disease | D000544 | EFO_0000249 | F03 | — | 3 | — | — | — | 3 |
| Tobacco use disorder | D014029 | — | F17 | — | 1 | — | — | — | 1 |
Indications Phases 1
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Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | POZANICLINE |
| INN | pozanicline |
| Description | A-84543 is a drug developed by Abbott, which acts as an agonist at neural nicotinic acetylcholine receptors with high selectivity for the α4β2 subtype. It is widely used in scientific research into the structure and function of this receptor subtype and has been the lead compound for the development of a large family of related derivatives.
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| Classification | Small molecule |
| Drug class | nicotinic acetylcholine receptor partial agonists/agonists |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | Cc1ncccc1OC[C@@H]1CCCN1 |
Identifiers
| PDB | — |
| CAS-ID | 161416-43-9 |
| RxCUI | — |
| ChEMBL ID | CHEMBL127071 |
| ChEBI ID | — |
| PubChem CID | 9794141 |
| DrugBank | — |
| UNII ID | CL2002R563 (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Trends
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Additional graphs summarizing 34 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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