PLEVITREXED
Plevitrexed is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target thymidylate synthase.
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Commercial
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Clinical
Clinical Trials
1 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | — | 1 | — | — | — | 1 |
| Fallopian tube neoplasms | D005185 | — | — | — | 1 | — | — | — | 1 |
| Ovarian epithelial carcinoma | D000077216 | — | — | — | 1 | — | — | — | 1 |
Indications Phases 1
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Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | PLEVITREXED |
| INN | plevitrexed |
| Description | Plevitrexed is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target thymidylate synthase. |
| Classification | Small molecule |
| Drug class | antineoplastic thymidylate synthetase inhibitors |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | C#CCN(Cc1cc2c(O)nc(C)nc2cc1C)c1ccc(C(=O)N[C@@H](CCc2nnn[nH]2)C(=O)O)c(F)c1 |
Identifiers
| PDB | — |
| CAS-ID | 153537-73-6 |
| RxCUI | — |
| ChEMBL ID | CHEMBL126648 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | L9P2881C3H (ChemIDplus, GSRS) |
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Safety
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