PHENDIMETRAZINE
Bontril Pdm, Phendimetrazine (phendimetrazine) is a small molecule pharmaceutical. Phendimetrazine was first approved as Phendimetrazine tartrate on 1982-01-01. It is used to treat obesity in the USA.
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Commercial
Therapeutic Areas
Trade Name
FDA
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Bontril pdm, Phendimetrazine (discontinued: Adphen, Alphazine, Bontril, Cam-metrazine, Di-metrex, Metra, Phendimetrazine, Plegine, Sprx, Statobex, X-trozine)
Drug Products
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Phendimetrazine tartrate
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| PHENDIMETRAZINE TARTRATE | Virtus Pharmaceuticals | N-018074 RX | 1982-01-01 | 1 products, RLD, RS |
Show 1 discontinued
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| phendimetrazine | ANDA | 2021-12-31 |
| phendimetrazine tartrate | ANDA | 2025-09-08 |
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| obesity | EFO_0001073 | D009765 | E66.9 |
Agency Specific
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Clinical
Clinical Trials
5 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
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Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Obesity | D009765 | EFO_0001073 | E66.9 | — | — | — | — | 1 | 1 |
| Overweight | D050177 | — | E66.3 | — | — | — | — | 1 | 1 |
| Pregnancy | D011247 | EFO_0002950 | Z33.1 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | PHENDIMETRAZINE |
| INN | phendimetrazine |
| Description | Phendimetrazine (Bontril, Adipost, Anorex-SR, Appecon, Melfiat, Obezine, Phendiet, Plegine, Prelu-2, Statobex) is a stimulant drug of the morpholine chemical class used as an appetite suppressant.
|
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC1C(c2ccccc2)OCCN1C |
Identifiers
| PDB | — |
| CAS-ID | 634-03-7 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1744 |
| ChEBI ID | — |
| PubChem CID | 12460 |
| DrugBank | DB01579 |
| UNII ID | AB2794W8KV (ChemIDplus, GSRS) |
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Phendimetrazine
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Additional graphs summarizing 343 documents
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Safety
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116 adverse events reported
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