Tradename | Company | Number | Date | Products |
---|---|---|---|---|
VISINE L.R. | Johnson & Johnson | N-019407 OTC | 1989-03-31 | 1 products, RLD, RS |
RHOFADE | Mayne Group | N-208552 RX | 2017-01-18 | 1 products, RLD, RS |
UPNEEQ | RVL Pharmaceuticals | N-212520 RX | 2020-07-08 | 1 products, RLD, RS |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
KOVANAZE | St Renatus | N-208032 RX | 2016-06-29 | 1 products, RLD, RS |
Brand Name | Status | Last Update |
---|---|---|
7 select original nasal | OTC monograph final | 2019-11-14 |
afrin | C200263 | 2024-12-06 |
afrin allergy sinus nasal | C200263 | 2024-12-06 |
afrin no drip | C200263 | 2024-12-06 |
afrin no drip night | C200263 | 2024-12-06 |
afrin no-drip | C200263 | 2024-12-06 |
afrin nodrip allergy sinus night | C200263 | 2024-12-06 |
afrin original | C200263 | 2024-12-18 |
afrin original nasal | C200263 | 2023-11-05 |
anefrin nasal | C200263 | 2024-09-07 |
Expiration | Code | ||
---|---|---|---|
OXYMETAZOLINE HYDROCHLORIDE, UPNEEQ, RVL PHARMS | |||
2023-07-08 | NP |
Patent | Expires | Flag | FDA Information |
---|---|---|---|
Oxymetazoline Hydrochloride, Upneeq, Rvl Pharms | |||
10799481 | 2039-12-16 | U-2849 | |
10814001 | 2039-12-16 | DP | |
10898573 | 2039-12-16 | DP | |
10940138 | 2039-12-16 | U-2849 | |
11103482 | 2039-12-16 | DP | |
11311515 | 2039-12-16 | DP | |
11324722 | 2039-12-16 | U-2849 | |
11541036 | 2039-12-16 | DP | |
8357714 | 2031-08-26 | U-2849 | |
9867808 | 2031-08-26 | U-2849 | |
10912765 | 2031-08-26 | U-2849 | |
Oxymetazoline Hydrochloride, Rhofade, Mayne Pharma | |||
9974773 | 2035-06-11 | U-2306 | |
10335391 | 2035-06-11 | U-2567 | |
10751325 | 2035-06-11 | U-2921 | |
11517560 | 2035-06-11 | U-3494 | |
8883838 | 2031-12-01 | DP | |
7812049 | 2028-05-02 | U-1959 | |
8420688 | 2024-08-02 | U-1959 | |
8815929 | 2024-01-22 | U-1959 | |
Oxymetazoline Hydrochloride / Tetracaine Hydrochloride, Kovanaze, St Renatus | |||
8580282 | 2030-04-02 | DP | U-1876 |
9308191 | 2030-04-02 | DP | U-1876 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Therapeutic equivalency | D013810 | — | — | 1 | — | — | — | — | 1 |
Drug common name | Oxymetazoline |
INN | oxymetazoline |
Description | Oxymetazoline is a member of the class of phenols that is 2,4-dimethylphenol which is substituted at positions 3 and 6 by 4,5-dihydro-1H-imidazol-2-ylmethyl and tert-butyl groups, respectively. A direct-acting sympathomimetic with marked alpha-adrenergic activity, it is a vasoconstrictor that is used (generally as the hydrochloride salt) to relieve nasal congestion. It has a role as an alpha-adrenergic agonist, a sympathomimetic agent, a nasal decongestant and a vasoconstrictor agent. It is a member of phenols, a carboxamidine and a member of imidazolines. It is a conjugate base of an oxymetazoline(1+). |
Classification | Small molecule |
Drug class | antihistamines/local vasoconstrictors (antazoline type) |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | Cc1cc(C(C)(C)C)c(O)c(C)c1CC1=NCCN1 |
PDB | — |
CAS-ID | 1491-59-4 |
RxCUI | — |
ChEMBL ID | CHEMBL762 |
ChEBI ID | 7862 |
PubChem CID | 4636 |
DrugBank | DB00935 |
UNII ID | 8VLN5B44ZY (ChemIDplus, GSRS) |