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Drug ReportsOxybenzone
Oxybenzone
Shade Uvaguard (oxybenzone) is a small molecule pharmaceutical. Oxybenzone was first approved as Shade uvaguard on 1992-12-07. It is used to treat photosensitivity disorders in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
skin and connective tissue diseasesD017437
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Avobenzone
+
Octinoxate
+
Oxybenzone
Tradename
Company
Number
Date
Products
SHADE UVAGUARDBayerN-020045 DISCN1992-12-07
1 products, RLD
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Labels
FDA
EMA
Brand Name
Status
Last Update
OTC monograph not final2013-01-10
24k skin tone moisturizer spf 30OTC monograph not final2022-07-25
2x sunblock spf 50OTC monograph final2011-04-28
4-in-1 broad spectrum spf 50 sunscreenOTC monograph final2020-08-19
70 dry touch spf 70OTC monograph not final2018-07-19
academy continuousOTC monograph not final2013-08-30
academy continuous sportOTC monograph not final2013-08-27
academy spf 50OTC monograph not final2016-07-20
academy sportOTC monograph not final2013-06-28
active radiance day moisture spf 30C2002632023-10-19
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Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
photosensitivity disordersHP_0000992D010787L57.1
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
No data
HCPCS
No data
Clinical
Clinical Trials
11 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
MelanosisD008548HP_0001480L81.1———1—1
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Sun protection factorD059405————1——1
Indications Phases 2
No data
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
MelanomaD008545——1————1
Skin neoplasmsD012878EFO_0004198C441————1
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
DermatitisD003872HP_0011123L30.9————11
Photoallergic dermatitisD017454——————11
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameOxybenzone
INNoxybenzone
Description
Oxybenzone is a hydroxybenzophenone that is benzophenone which is substituted at the 2- and 4-positions of one of the benzene rings by hydroxy and methoxy groups respectively. It has a role as a dermatologic drug, a protective agent, an ultraviolet filter, a xenobiotic and an environmental contaminant. It is a hydroxybenzophenone and a monomethoxybenzene.
Classification
Small molecule
Drug class—
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
COc1ccc(C(=O)c2ccccc2)c(O)c1
Identifiers
PDB—
CAS-ID131-57-7
RxCUI—
ChEMBL IDCHEMBL1625
ChEBI ID34283
PubChem CID4632
DrugBankDB01428
UNII ID95OOS7VE0Y (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 773 documents
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Safety
Black-box Warning
Black-box warning for: Skin tint fx
Adverse Events
Top Adverse Reactions
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13,119 adverse events reported
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