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Drug ReportsOxacillin
Oxacillin
Bactocill, Oxacillin (oxacillin) is a small molecule pharmaceutical. Oxacillin was first approved as Prostaphlin on 1982-01-01. It is used to treat bacterial endocarditis, bacterial infections, bacterial meningitis, cellulitis, and osteomyelitis amongst others in the USA.
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Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
musculoskeletal diseasesD009140
respiratory tract diseasesD012140
nervous system diseasesD009422
urogenital diseasesD000091642
cardiovascular diseasesD002318
skin and connective tissue diseasesD017437
signs and symptoms pathological conditionsD013568
Trade Name
FDA
EMA
Bactocill (generic drugs available since 2012-03-30, discontinued: Prostaphlin)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Oxacillin sodium
Tradename
Company
Number
Date
Products
BACTOCILL IN PLASTIC CONTAINERBaxterN-050640 RX1989-10-26
2 products, RLD, RS
Show 3 discontinued
Labels
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
J: Antiinfectives for systemic use
J01: Antibacterials for systemic use
J01C: Beta-lactam antibacterials, penicillins
J01CF: Beta-lactamase resistant penicillins
J01CF04: Oxacillin
HCPCS
Code
Description
J2700
Injection, oxacillin sodium, up to 250 mg
Clinical
Clinical Trials
25 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
BacteremiaD016470EFO_0003033R78.812215
CellulitisD002481EFO_0003035L03.90112
EndocarditisD004696HP_0100584112
Infectious skin diseasesD01287411
Renal insufficiencyD051437HP_0000083N1911
Indications Phases 3
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Wound infectionD01494611
AbscessD000038EFO_000303011
UlcerD014456MPATH_57911
BurnsD002056T30.011
Indications Phases 1
No data
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Rheumatoid arthritisD001172EFO_0000685M06.911
Major depressive disorderD003865EFO_0003761F2211
Staphylococcal infectionsD013203A49.0111
Surgical wound infectionD01353011
PneumoniaD011014EFO_000310611
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameOxacillin
INNoxacillin
Description
Oxacillin is a penicillin antibiotic carrying a 5-methyl-3-phenylisoxazole-4-carboxamide group at position 6beta. It has a role as an antibacterial agent and an antibacterial drug. It is a conjugate acid of an oxacillin(1-).
Classification
Small molecule
Drug classpenicillins
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
Cc1onc(-c2ccccc2)c1C(=O)N[C@@H]1C(=O)N2[C@@H](C(=O)O)C(C)(C)S[C@H]12
Identifiers
PDB
CAS-ID66-79-5
RxCUI
ChEMBL IDCHEMBL819
ChEBI ID7809
PubChem CID6196
DrugBankDB00713
UNII IDUH95VD7V76 (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
Revenue by drug
$
£
No data
Estimated US medical usage
Oxacillin
Total medical expenditures per year (USD, in millions)
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Number of persons purchased
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Number of purchases
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Refill frequency
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Price per prescription (USD)
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Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 16,602 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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3,318 adverse events reported
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