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AboutPricing
Drug ReportsOxacillin
Oxacillin
Bactocill, Oxacillin (oxacillin) is a small molecule pharmaceutical. Oxacillin was first approved as Prostaphlin on 1982-01-01. It is used to treat bacterial endocarditis, bacterial infections, bacterial meningitis, cellulitis, and osteomyelitis amongst others in the USA.
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Variants
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Events Timeline
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6M
YTD
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2Y
5Y
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FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
musculoskeletal diseasesD009140
respiratory tract diseasesD012140
nervous system diseasesD009422
urogenital diseasesD000091642
cardiovascular diseasesD002318
skin and connective tissue diseasesD017437
signs and symptoms pathological conditionsD013568
Trade Name
FDA
EMA
Bactocill, Oxacillin (discontinued: Bactocill, Oxacillin, Prostaphlin)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Oxacillin sodium
Tradename
Company
Number
Date
Products
BACTOCILL IN PLASTIC CONTAINERBaxterN-050640 RX1989-10-26
2 products, RLD, RS
Show 3 discontinued
Labels
FDA
EMA
Brand Name
Status
Last Update
oxacillinANDA2024-07-19
oxacillin oxacillinANDA2022-11-10
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
respiratory tract infections—D012141J06.9
postoperative complications—D011183—
urinary tract infectionsEFO_0003103D014552N39.0
bacterial infections—D001424A49
osteomyelitisEFO_0003102D010019M86
wound infection—D014946—
staphylococcal infections—D013203A49.01
bacterial endocarditisEFO_1000830D004697—
bacterial meningitisEFO_1000831D016920G00
cellulitisEFO_0003035D002481L03.90
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
J: Antiinfectives for systemic use
— J01: Antibacterials for systemic use
— J01C: Beta-lactam antibacterials, penicillins
— J01CF: Beta-lactamase resistant penicillins
— J01CF04: Oxacillin
HCPCS
Code
Description
J2700
Injection, oxacillin sodium, up to 250 mg
Clinical
Clinical Trials
27 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
InfectionsD007239EFO_0000544——433212
Communicable diseasesD003141———333211
BacteremiaD016470EFO_0003033R78.81—32117
Bacterial skin diseasesD017192———111—3
CellulitisD002481EFO_0003035L03.90—111—3
Infectious skin diseasesD012874————11—2
PneumoniaD011014EFO_0003106————112
Soft tissue infectionsD018461————11—2
EndocarditisD004696HP_0100584———11—2
Skin diseasesD012871—L00-L99———1—1
Show 5 more
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Bacterial infectionsD001424—A49—12—14
Gram-positive bacterial infectionsD016908———31——4
OsteomyelitisD010019EFO_0003102M86111——3
Methicillin-resistant staphylococcus aureusD055624————1——1
Staphylococcal skin infectionsD013207EFO_1001849L00——1——1
Bacterial endocarditisD004697EFO_1000830———1——1
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Infectious arthritisD001170EFO_1001351M00—1———1
SepsisD018805HP_0100806A41.9—1———1
Wound infectionD014946———1———1
AbscessD000038EFO_0003030——1———1
UlcerD014456MPATH_579——1———1
BurnsD002056—T30.0—1———1
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Bacterial vaginosisD016585EFO_0003932—1————1
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Staphylococcal infectionsD013203—A49.01————22
Rheumatoid arthritisD001172EFO_0000685M06.9————11
Major depressive disorderD003865EFO_0003761F22————11
Depressive disorderD003866EFO_1002014F32.A————11
Surgical wound infectionD013530——————11
Respiratory tract infectionsD012141—J06.9————11
Respiratory syncytial virusesD012136——————11
CoinfectionD060085——————11
HypersensitivityD006967HP_0012393T78.40————11
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameOxacillin
INNoxacillin
Description
Oxacillin is a penicillin antibiotic carrying a 5-methyl-3-phenylisoxazole-4-carboxamide group at position 6beta. It has a role as an antibacterial agent and an antibacterial drug. It is a conjugate acid of an oxacillin(1-).
Classification
Small molecule
Drug classpenicillins
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Structure (InChI/SMILES or Protein Sequence)
Cc1onc(-c2ccccc2)c1C(=O)N[C@@H]1C(=O)N2[C@@H](C(=O)O)C(C)(C)S[C@H]12
Identifiers
PDB—
CAS-ID66-79-5
RxCUI—
ChEMBL IDCHEMBL819
ChEBI ID7809
PubChem CID6196
DrugBankDB00713
UNII IDUH95VD7V76 (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
Revenue by drug
$
€
£
₣
No data
Estimated US medical usage
Oxacillin
Total medical expenditures per year (USD, in millions)
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Number of persons purchased
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Number of purchases
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Refill frequency
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Price per prescription (USD)
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Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 17,388 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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4,228 adverse events reported
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