Otilimab
Otilimab is an antibody pharmaceutical. It is currently being investigated in clinical studies. The pharmaceutical is active against granulocyte-macrophage colony-stimulating factor.
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Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
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Completion date
Results first post date
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Commercial
No data
Clinical
Clinical Trials
13 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Rheumatoid arthritis | D001172 | EFO_0000685 | M06.9 | 2 | 3 | 4 | — | 1 | 9 |
| Arthritis | D001168 | EFO_0005856 | M05-M14 | 2 | 3 | 4 | — | 1 | 9 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Covid-19 | D000086382 | — | U07.1 | — | 1 | — | — | — | 1 |
| Respiratory distress syndrome | D012128 | EFO_1000637 | J80 | — | 1 | — | — | — | 1 |
| Severe acute respiratory syndrome | D045169 | EFO_0000694 | J12.81 | — | 1 | — | — | — | 1 |
| Osteoarthritis | D010003 | EFO_0002506 | M15-M19 | — | 1 | — | — | — | 1 |
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Otilimab |
| INN | otilimab |
| Description | MOR-103 (human mab) |
| Classification | Antibody |
| Drug class | monoclonal antibodies |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL2109433 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | Y8127R3VCH (ChemIDplus, GSRS) |
Target
Agency Approved
CSF2
CSF2
Organism
Homo sapiens
Gene name
CSF2
Gene synonyms
GMCSF
NCBI Gene ID
Protein name
granulocyte-macrophage colony-stimulating factor
Protein synonyms
colony stimulating factor 2 (granulocyte-macrophage), Colony-stimulating factor, CSF, granulocyte macrophage-colony stimulating factor, molgramostim, Molgramostin, Sargramostim
Uniprot ID
Mouse ortholog
Csf2 (12981)
granulocyte-macrophage colony-stimulating factor (P01587)
Alternate
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 326 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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39 adverse events reported
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