Olezarsen
Olezarsen is an oligonucleotide pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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Clinical
Clinical Trials
12 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hypertriglyceridemia | D015228 | EFO_0004211 | — | 1 | 2 | 4 | — | — | 7 |
| Syndrome | D013577 | — | — | — | — | 3 | — | 1 | 4 |
| Hyperlipoproteinemia type i | D008072 | Orphanet_411 | E78.3 | — | — | 3 | — | 1 | 4 |
| Cardiovascular diseases | D002318 | HP_0001626 | — | — | 2 | 1 | — | — | 3 |
| Atherosclerosis | D050197 | EFO_0003914 | I25.1 | — | 1 | 1 | — | — | 2 |
Indications Phases 2
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Olezarsen |
| INN | olezarsen |
| Description | Olezarsen is a drug designed to block the production of apolipoprotein C-III and lower its concentrations to treat people with familial hypercholesterolemia and hypertriglyceridemia.
|
| Classification | Oligonucleotide |
| Drug class | antisense oligonucleotides |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL4650438 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | S3RS2SA30L (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Trends
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Additional graphs summarizing 87 documents
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Safety
Black-box Warning
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Adverse Events
0 adverse events reported
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