Drug common name | Triapine |
INN | — |
Description | 3-Aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP, also called Triapine) is substance of interest for the treatment of cancer. It is a thiosemicarbazone derivative of 3-aminopyridine-2-carboxaldehyde. It presents an N-N-S array of donor sites that strongly bind iron, robbing iron-containing enzymes of their prosthetic group.
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Classification | Small molecule |
Drug class | tricyclic compounds |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | NC(=S)N/N=C/c1ncccc1N |
PDB | — |
CAS-ID | 143621-35-6 |
RxCUI | — |
ChEMBL ID | CHEMBL231616 |
ChEBI ID | — |
PubChem CID | 9571836 |
DrugBank | — |
UNII ID | — |