Ocx-0191 - PharmaKB

Triapine

Triapine is a small molecule pharmaceutical. It is currently being investigated in clinical studies.

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Commercial

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Clinical

Clinical Trials

216 clinical trials

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Indications Phases 4

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Indications Phases 3

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Indications Phases 2

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Indications Phases 1

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Indications Without Phase

Indication	MeSH	Ontology	ICD-10	Ph 1	Ph 2	Ph 3	Ph 4	Other	Total
Schizophrenia	D012559	EFO_0000692	F20	—	—	—	—	1	1

Epidemiology

Epidemiological information for investigational and approved indications

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Drug

General

Drug common name	Triapine
INN	—
Description	3-Aminopyridine-2-carboxaldehyde thiosemicarbazone (3-AP, also called Triapine) is substance of interest for the treatment of cancer. It is a thiosemicarbazone derivative of 3-aminopyridine-2-carboxaldehyde. It presents an N-N-S array of donor sites that strongly bind iron, robbing iron-containing enzymes of their prosthetic group.
Classification	Small molecule
Drug class	tricyclic compounds
Image (chem structure or protein)
Structure (InChI/SMILES or Protein Sequence)	NC(=S)N/N=C/c1ncccc1N