

Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Alzheimer disease | D000544 | EFO_0000249 | F03 | — | 2 | — | — | — | 2 |
| Central nervous system diseases | D002493 | — | G96.9 | — | 2 | — | — | — | 2 |
| Brain diseases | D001927 | — | G93.40 | — | 2 | — | — | — | 2 |
| Nervous system diseases | D009422 | — | G00-G99 | — | 2 | — | — | — | 2 |
| Dementia | D003704 | EFO_0003862 | F03 | — | 2 | — | — | — | 2 |
| Mental disorders | D001523 | EFO_0000677 | F91.9 | — | 2 | — | — | — | 2 |
| Drug common name | OSUGACESTAT |
| INN | osugacestat |
| Description | (2S,3R)-N'-[(3S)-1-methyl-2-oxo-5-phenyl-3H-1,4-benzodiazepin-3-yl]-2,3-bis(3,3,3-trifluoropropyl)butanediamide is a primary carboxamide, a secondary carboxamide and a tertiary carboxamide. |
| Classification | Small molecule |
| Drug class | enzyme inhibitors: gamma secretase inhibitors |
| Image (chem structure or protein) | ![]() |
| Structure (InChI/SMILES or Protein Sequence) | CN1C(=O)[C@@H](NC(=O)[C@H](CCC(F)(F)F)[C@H](CCC(F)(F)F)C(N)=O)N=C(c2ccccc2)c2ccccc21 |
| PDB | — |
| CAS-ID | 1401066-79-2 |
| RxCUI | — |
| ChEMBL ID | CHEMBL4297269 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | DRL23N424R (ChemIDplus, GSRS) |
