ORISMILAST
Orismilast is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Events Timeline
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Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
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Completion date
Results first post date
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Commercial
No data
Clinical
Clinical Trials
13 clinical trials
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Indications Phases 4
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Indications Phases 3
No data
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Psoriasis | D011565 | EFO_0000676 | L40 | 4 | 2 | — | — | — | 6 |
| Atopic dermatitis | D003876 | EFO_0000274 | L20 | 1 | 1 | — | — | — | 2 |
| Eczema | D004485 | — | L30.9 | 1 | 1 | — | — | — | 2 |
| Dermatitis | D003872 | — | L30.9 | 1 | 1 | — | — | — | 2 |
| Skin diseases | D012871 | — | L00-L99 | — | 2 | — | — | — | 2 |
| Hidradenitis suppurativa | D017497 | — | L73.2 | — | 1 | — | — | — | 1 |
| Hidradenitis | D016575 | — | — | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 3 | — | — | — | — | 3 |
| Drug interactions | D004347 | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | ORISMILAST |
| INN | orismilast |
| Description | Orismilast is a small molecule pharmaceutical. It is currently being investigated in clinical studies. |
| Classification | Small molecule |
| Drug class | antiasthmatics/antiallergics (not acting primarily as antihistamines): type IV phosphodiesterase |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | O=C(Cc1c(Cl)c[n+]([O-])cc1Cl)c1ccc(OC(F)F)c2c1OC1(CCS(=O)(=O)CC1)O2 |
Identifiers
| PDB | — |
| CAS-ID | 1353546-86-7 |
| RxCUI | — |
| ChEMBL ID | CHEMBL3654384 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | JH1CX8SG5V (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Trends
PubMed Central
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Additional graphs summarizing 36 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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