PharmaKB logo
Company Reports
Company Reports
Drug Reports
Drug Reports
Disease Reports
Disease Reports
Sets
Sets
Favorites
Favorites
Log in
Log in
AboutPricing
Drug ReportsNorelgestromin
Ortho evra, Evra(norelgestromin)
Ethinyl Estradiol / Norelgestromin, Evra, Onsura, Xulane (norelgestromin) is a small molecule pharmaceutical. Norelgestromin was first approved as Ortho evra on 2001-11-20. It is used to treat amenorrhea and uterine hemorrhage in the USA. It has been approved in Europe to treat contraception.
Download report
Favorite
Events Timeline
Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
Plot placeholder
Mock data
Subscribe for the real data
Commercial
Therapeutic Areas
Therapeutic Area
MeSH
urogenital diseasesD000091642
signs and symptoms pathological conditionsD013568
therapeuticsD013812
Trade Name
FDA
EMA
Combinations
Ethinyl estradiol norelgestromin, Onsura, Xulane (discontinued: Ortho evra)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Ethinyl estradiol
+
Norelgestromin
Tradename
Company
Number
Date
Products
ORTHO EVRAJohnson & JohnsonN-021180 DISCN2001-11-20
1 products, RLD
Hide discontinued
Labels
FDA
EMA
Brand Name
Status
Last Update
norelgestromin and ethinly estradiolANDA2022-03-30
norelgestromin and ethinyl estradiolANDA2024-11-27
xulaneANDA2024-02-27
zafemyANDA2024-01-05
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
prostatic neoplasms—D011471C61
breast neoplasmsEFO_0003869D001943C50
menorrhagiaEFO_0003945D008595N92.0
uterine hemorrhage—D014592—
primary ovarian insufficiencyEFO_0004266D016649E28.3
amenorrhea—D000568N91.2
hot flashes—D019584—
hypogonadism—D007006E23.0
premature menopause—D008594E28.31
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
G: Genito urinary system and sex hormones
— G03: Sex hormones and modulators of the genital system
— G03A: Hormonal contraceptives for systemic use
— G03AA: Progestogens and estrogen systemic contraceptives, fixed combinations
— G03AA13: Norelgestromin and ethinylestradiol
HCPCS
No data
Clinical
Clinical Trials
49 clinical trials
View more details
Plot placeholder
Mock data
Subscribe for the real data
Indications Phases 4
No data
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
ContraceptionD003267———11——2
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
Drug common nameNorelgestromin
INNnorelgestromin
Description
Norelgestromin, or norelgestromine, sold under the brand names Evra and Ortho Evra among others, is a progestin medication which is used as a method of birth control for women. The medication is available in combination with an estrogen and is not available alone. It is used as a patch that is applied to the skin.
Classification
Small molecule
Drug classestrogens; progestins
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
C#C[C@]1(O)CC[C@H]2[C@@H]3CCC4=C/C(=N/O)CC[C@@H]4[C@H]3CC[C@@]21CC
Identifiers
PDB—
CAS-ID53016-31-2
RxCUI—
ChEMBL IDCHEMBL1200807
ChEBI ID—
PubChem CID62930
DrugBankDB06713
UNII IDR0TAY3X631 (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
Revenue by drug
$
€
£
₣
No data
Estimated US medical usage
Norelgestromin
+
Ethinyl estradiol
Total medical expenditures per year (USD, in millions)
Plot placeholder
Mock data
Subscribe for the real data
Number of persons purchased
Plot placeholder
Mock data
Subscribe for the real data
Number of purchases
Plot placeholder
Mock data
Subscribe for the real data
Refill frequency
Plot placeholder
Mock data
Subscribe for the real data
Price per prescription (USD)
Plot placeholder
Mock data
Subscribe for the real data
Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Plot placeholder
Mock data
Subscribe for the real data
Additional graphs summarizing 564 documents
View more details
Safety
Black-box Warning
Black-box warning for: Norelgestromin and ethinly estradiol, Norelgestromin and ethinyl estradiol, Xulane, Zafemy
Adverse Events
Top Adverse Reactions
Plot placeholder
Mock data
Subscribe for the real data
23,485 adverse events reported
View more details
© 2020-2025 Collaborative Drug Discovery Inc. (CDD) | Terms of Use