Nomegestrol
Ioa, Zoely (nomegestrol) is a small molecule pharmaceutical. Nomegestrol was first approved as Zoely on 2011-07-26. It has been approved in Europe to treat contraception.
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Commercial
Therapeutic Areas
Therapeutic Area | MeSH |
|---|---|
| therapeutics | D013812 |
Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
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Indications
FDA
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Agency Specific
FDA
EMA
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Patent Expiration
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ATC Codes
G: Genito urinary system and sex hormones
— G03: Sex hormones and modulators of the genital system
— G03A: Hormonal contraceptives for systemic use
— G03AA: Progestogens and estrogen systemic contraceptives, fixed combinations
— G03AA14: Nomegestrol and estradiol
— G03D: Progestogen sex hormones and modulators of the genital system
— G03DB: Pregnadien derivatives, progestogens
— G03DB04: Nomegestrol
— G03F: Progestogens and estrogens in combination
— G03FB: Progestogens and estrogens, sequential preparations
— G03FB12: Nomegestrol and estrogen
HCPCS
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Clinical
Clinical Trials
22 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Contraception | D003267 | — | — | — | 1 | 8 | 1 | 1 | 11 |
| Ovulation inhibition | D034445 | — | — | — | 1 | — | 1 | — | 2 |
| Uterine diseases | D014591 | — | N85.9 | — | — | — | 2 | — | 2 |
| Thrombophilia | D019851 | — | D68.59 | — | — | — | 1 | — | 1 |
| Hemorrhage | D006470 | MP_0001914 | R58 | — | — | — | 1 | — | 1 |
| Menorrhagia | D008595 | EFO_0003945 | N92.0 | — | — | — | 1 | — | 1 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Recurrence | D012008 | — | — | — | — | 1 | — | — | 1 |
| Multiple sclerosis | D009103 | EFO_0003885 | G35 | — | — | 1 | — | — | 1 |
| Sclerosis | D012598 | — | — | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Dysmenorrhea | D004412 | — | N94.6 | — | 1 | — | — | 1 | 2 |
| Uterine hemorrhage | D014592 | — | — | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 1 | — | — | — | — | 1 |
| Therapeutic equivalency | D013810 | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Chronic pain | D059350 | — | — | — | — | — | — | 1 | 1 |
| Pelvic pain | D017699 | — | — | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Nomegestrol |
| INN | nomegestrol |
| Description | Nomegestrol is a corticosteroid hormone. |
| Classification | Small molecule |
| Drug class | estrogens; progestins |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC(=O)[C@@]1(O)CC[C@H]2[C@@H]3C=C(C)C4=CC(=O)CC[C@@H]4[C@H]3CC[C@@]21C |
Identifiers
| PDB | — |
| CAS-ID | 58691-88-6 |
| RxCUI | — |
| ChEMBL ID | CHEMBL2105722 |
| ChEBI ID | — |
| PubChem CID | 68783 |
| DrugBank | — |
| UNII ID | 10F89177CO (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Trends
PubMed Central
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Safety
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Adverse Events
Top Adverse Reactions
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293 adverse events reported
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