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Drug ReportsNitroprusside
Nitroprusside
Nipride, Nitroprusside (nitroprusside) is a small molecule pharmaceutical. Nitroprusside was first approved as Nitropress on 1982-01-01.
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Target
Variants
Financial
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Safety
Events Timeline
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FDA approval date
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Study first post date
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Completion date
Results first post date
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
Nipride, Nitroprusside (discontinued: Nipride, Nitropress, Nitroprusside)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Sodium nitroprusside
Tradename
Company
Number
Date
Products
NIPRIDE RTU IN SODIUM CHLORIDE 0.9%Exela Pharma SciencesN-209387 RX2017-03-08
2 products, RLD, RS
Show 4 discontinued
Labels
FDA
EMA
Brand Name
Status
Last Update
nipride rtuNew Drug Application2018-07-20
sodium nitroprussideANDA2025-02-16
sodium nitroprusside in 0.9% sodium chlorideANDA2023-11-15
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
C: Cardiovascular system drugs
— C02: Antihypertensives
— C02D: Arteriolar smooth muscle, agents acting on
— C02DD: Nitroferricyanide derivatives acting on arteriolar smooth muscle
— C02DD01: Nitroprusside
HCPCS
No data
Clinical
Clinical Trials
107 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
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Indications Phases 1
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Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Type 2 diabetes mellitusD003924EFO_0001360E11————11
Diabetes mellitusD003920EFO_0000400E08-E13————11
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameNitroprusside
INN_
Description
Sodium nitroprusside (SNP), sold under the brand name Nitropress among others, is a medication used to lower blood pressure. This may be done if the blood pressure is very high and resulting in symptoms, in certain types of heart failure, and during surgery to decrease bleeding. It is used by continuous injection into a vein. Onset is typically immediate and effects last for up to ten minutes.
Classification
Small molecule
Drug classatropine derivatives
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Structure (InChI/SMILES or Protein Sequence)—
Identifiers
PDB—
CAS-ID13755-38-9
RxCUI—
ChEMBL IDCHEMBL2097081
ChEBI ID7596
PubChem CID11953895
DrugBankDB00325
UNII IDEAO03PE1TC (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 23,949 documents
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Safety
Black-box Warning
Black-box warning for: Nipride rtu, Sodium nitroprusside, Sodium nitroprusside in 0.9% sodium chloride
Adverse Events
Top Adverse Reactions
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262 adverse events reported
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