Therapeutic Area | MeSH |
---|---|
infections | D007239 |
urogenital diseases | D000091642 |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
FURADANTIN | Casper Pharma | N-009175 RX | 1982-01-01 | 2 products, RLD |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
MACROBID | Almatica Pharma | N-020064 RX | 1991-12-24 | 1 products, RLD, RS |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
IVADANTIN | Procter And Gamble | N-012402 DISCN | 1982-01-01 | 1 products |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
MACRODANTIN | Almatica Pharma | N-016620 RX | 1982-01-01 | 3 products, RLD |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Urinary tract infections | D014552 | EFO_0003103 | N39.0 | 1 | 4 | 4 | 16 | 7 | 32 |
Cystitis | D003556 | EFO_1000025 | N30 | — | 1 | — | 4 | — | 5 |
Pyelonephritis | D011704 | EFO_1001141 | N10-N16 | — | — | 1 | 2 | — | 3 |
Nephrolithiasis | D053040 | — | N20.0 | — | — | — | 1 | 1 | 2 |
Pelvic organ prolapse | D056887 | EFO_0004710 | — | — | — | — | 1 | 1 | 2 |
Pulpitis | D011671 | EFO_1001139 | K04.0 | — | — | — | 2 | — | 2 |
Overactive urinary bladder | D053201 | EFO_1000781 | N32.81 | — | — | — | 1 | — | 1 |
Urinary bladder neoplasms | D001749 | — | C67 | — | — | — | 1 | — | 1 |
Enterobacteriaceae infections | D004756 | EFO_1001313 | — | — | — | — | 1 | — | 1 |
Kidney calculi | D007669 | EFO_0004253 | N20 | — | — | — | 1 | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Chronic renal insufficiency | D051436 | — | N18 | — | — | 1 | — | — | 1 |
Vesico-ureteral reflux | D014718 | EFO_0007536 | N13.7 | — | — | 1 | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Kidney diseases | D007674 | EFO_0003086 | N08 | 1 | 1 | — | — | — | 1 |
Kidney transplantation | D016030 | — | — | 1 | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Healthy volunteers/patients | — | — | — | 3 | — | — | — | 1 | 4 |
Osteomyelitis | D010019 | EFO_0003102 | M86 | 1 | — | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Sepsis | D018805 | HP_0100806 | A41.9 | — | — | — | — | 1 | 1 |
Chemical and drug induced liver injury | D056486 | EFO_0004228 | — | — | — | — | — | 1 | 1 |
Asymptomatic infections | D058345 | — | — | — | — | — | — | 1 | 1 |
Bacteriuria | D001437 | — | R82.71 | — | — | — | — | 1 | 1 |
Urinary incontinence | D014549 | HP_0000020 | R32 | — | — | — | — | 1 | 1 |
Hypospadias | D007021 | EFO_0004209 | Q54 | — | — | — | — | 1 | 1 |
Asymptomatic diseases | D058070 | — | — | — | — | — | — | 1 | 1 |
Hematuria | D006417 | HP_0000790 | R31 | — | — | — | — | 1 | 1 |
Conization | D019092 | — | — | — | — | — | — | 1 | 1 |
Pregnancy complications | D011248 | — | — | — | — | — | — | 1 | 1 |
Drug common name | Nitrofurantoin |
INN | nitrofurantoin |
Description | Nitrofurantoin is an imidazolidine-2,4-dione that is hydantoin substituted at position 1 by a [(5-nitro-2-furyl)methylene]amino group. An antibiotic that damages bacterial DNA. It has a role as a hepatotoxic agent, an antiinfective agent and an antibacterial drug. It is an organonitrogen heterocyclic antibiotic, an organooxygen heterocyclic antibiotic, a nitrofuran antibiotic and an imidazolidine-2,4-dione. It is functionally related to a semicarbazide. |
Classification | Small molecule |
Drug class | antiepileptics (hydantoin derivatives) |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | O=C1CN(/N=C/c2ccc([N+](=O)[O-])o2)C(=O)N1 |
PDB | — |
CAS-ID | 67-20-9 |
RxCUI | — |
ChEMBL ID | CHEMBL572 |
ChEBI ID | 71415 |
PubChem CID | 6604200 |
DrugBank | DB00698 |
UNII ID | 927AH8112L (ChemIDplus, GSRS) |