Therapeutic Area | MeSH |
---|---|
infections | D007239 |
urogenital diseases | D000091642 |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
MACROBID | Almatica Pharma | N-020064 RX | 1991-12-24 | 1 products, RLD, RS |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
FURADANTIN | Casper Pharma | N-009175 RX | 1982-01-01 | 2 products, RLD |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
IVADANTIN | Procter And Gamble | N-012402 DISCN | 1982-01-01 | 1 products |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
MACRODANTIN | Almatica Pharma | N-016620 RX | 1982-01-01 | 3 products, RLD |
Brand Name | Status | Last Update |
---|---|---|
furadantin | New Drug Application | 2024-03-28 |
macrobid | New Drug Application | 2025-03-17 |
macrodantin | New Drug Application | 2023-06-01 |
nitrofurantion macrocrystals | New Drug Application | 2018-06-05 |
nitrofurantoin | ANDA | 2025-03-26 |
nitrofurantoin (macrocrystals) | ANDA | 2024-10-15 |
nitrofurantoin (monohydrate/macrocrystals) | ANDA | 2025-03-26 |
nitrofurantoin macrocrystals | ANDA | 2025-04-09 |
nitrofurantoin mono | New Drug Application | 2022-10-09 |
nitrofurantoin monohydrate macrocrystalline | New Drug Application | 2020-12-14 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Urinary tract infections | D014552 | EFO_0003103 | N39.0 | — | 1 | — | — | — | 1 |
Cystitis | D003556 | EFO_1000025 | N30 | — | 1 | — | — | — | 1 |
Drug common name | Nitrofurantoin |
INN | nitrofurantoin |
Description | Nitrofurantoin is an imidazolidine-2,4-dione that is hydantoin substituted at position 1 by a [(5-nitro-2-furyl)methylene]amino group. An antibiotic that damages bacterial DNA. It has a role as a hepatotoxic agent, an antiinfective agent and an antibacterial drug. It is an organonitrogen heterocyclic antibiotic, an organooxygen heterocyclic antibiotic, a nitrofuran antibiotic and an imidazolidine-2,4-dione. It is functionally related to a semicarbazide. |
Classification | Small molecule |
Drug class | antiepileptics (hydantoin derivatives) |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | O=C1CN(/N=C/c2ccc([N+](=O)[O-])o2)C(=O)N1 |
PDB | — |
CAS-ID | 67-20-9 |
RxCUI | — |
ChEMBL ID | CHEMBL572 |
ChEBI ID | 71415 |
PubChem CID | 6604200 |
DrugBank | DB00698 |
UNII ID | 927AH8112L (ChemIDplus, GSRS) |