Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Epilepsy | D004827 | EFO_0000474 | G40.9 | — | 1 | — | 2 | — | 3 |
Intellectual disability | D008607 | EFO_0003847 | F73 | — | — | — | 1 | — | 1 |
Drug resistant epilepsy | D000069279 | — | — | — | — | — | 1 | — | 1 |
Drug-related side effects and adverse reactions | D064420 | — | T88.7 | — | — | — | 1 | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Anxiety disorders | D001008 | EFO_0006788 | F41.1 | 1 | 1 | 1 | — | — | 2 |
Dementia | D003704 | EFO_0003862 | F03 | — | — | 1 | — | — | 1 |
Psychophysiologic disorders | D011602 | — | F45.9 | — | — | 1 | — | — | 1 |
Schizophrenia | D012559 | EFO_0000692 | F20 | — | — | 1 | — | — | 1 |
Depression | D003863 | — | F33.9 | — | — | 1 | — | — | 1 |
Somatoform disorders | D013001 | — | F45 | — | — | 1 | — | — | 1 |
Sleep initiation and maintenance disorders | D007319 | — | F51.01 | — | — | 1 | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Heart failure | D006333 | EFO_0003144 | I50 | — | 1 | — | — | — | 1 |
Vascular diseases | D014652 | EFO_0004264 | I77 | — | 1 | — | — | — | 1 |
Spasm | D013035 | — | M62.83 | — | 1 | — | — | — | 1 |
Infantile spasms | D013036 | EFO_1000643 | G40.82 | — | 1 | — | — | — | 1 |
Nerve block | D009407 | — | — | 1 | 1 | — | — | — | 1 |
Anxiety | D001007 | EFO_0005230 | F41.1 | 1 | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Autism spectrum disorder | D000067877 | — | F84.0 | — | — | — | — | 1 | 1 |
Carcinoma | D002277 | — | C80.0 | — | — | — | — | 1 | 1 |
Hepatocellular carcinoma | D006528 | — | C22.0 | — | — | — | — | 1 | 1 |
Therapeutic chemoembolization | D016461 | — | — | — | — | — | — | 1 | 1 |
Rheumatoid arthritis | D001172 | EFO_0000685 | M06.9 | — | — | — | — | 1 | 1 |
Arthritis | D001168 | EFO_0005856 | M05-M14 | — | — | — | — | 1 | 1 |
Chronic pain | D059350 | — | — | — | — | — | — | 1 | 1 |
Colorectal neoplasms | D015179 | — | — | — | — | — | — | 1 | 1 |
Neoplasms | D009369 | — | C80 | — | — | — | — | 1 | 1 |
Liver neoplasms | D008113 | EFO_1001513 | C22.0 | — | — | — | — | 1 | 1 |
Drug common name | Nitrazepam |
INN | nitrazepam |
Description | Nitrazepam is a 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one which is substituted at positions 5 and 7 by phenyl and nitro groups, respectively. It is used as a hypnotic for the short-term management of insomnia and for the treatment of epileptic spasms in infants (West's syndrome). It has a role as an anticonvulsant, an antispasmodic drug, a GABA modulator, a sedative and a drug metabolite. It is a 1,4-benzodiazepinone and a C-nitro compound. |
Classification | Small molecule |
Drug class | antianxiety agents (diazepam type) |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | O=C1CN=C(c2ccccc2)c2cc([N+](=O)[O-])ccc2N1 |
PDB | — |
CAS-ID | 146-22-5 |
RxCUI | — |
ChEMBL ID | CHEMBL13209 |
ChEBI ID | 7581 |
PubChem CID | 4506 |
DrugBank | DB01595 |
UNII ID | 9CLV70W7HS (ChemIDplus, GSRS) |