Nitrazepam
Nitrazepam is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Clinical
Clinical Trials
12 clinical trials
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Indications Phases 4
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Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Heart failure | D006333 | EFO_0003144 | I50 | — | 1 | — | — | — | 1 |
| Vascular diseases | D014652 | EFO_0004264 | I77 | — | 1 | — | — | — | 1 |
Indications Phases 1
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Nitrazepam |
| INN | nitrazepam |
| Description | Nitrazepam is a 1,4-benzodiazepinone that is 1,3-dihydro-2H-1,4-benzodiazepin-2-one which is substituted at positions 5 and 7 by phenyl and nitro groups, respectively. It is used as a hypnotic for the short-term management of insomnia and for the treatment of epileptic spasms in infants (West's syndrome). It has a role as an anticonvulsant, an antispasmodic drug, a GABA modulator, a sedative and a drug metabolite. It is a 1,4-benzodiazepinone and a C-nitro compound. |
| Classification | Small molecule |
| Drug class | antianxiety agents (diazepam type) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | O=C1CN=C(c2ccccc2)c2cc([N+](=O)[O-])ccc2N1 |
Identifiers
| PDB | — |
| CAS-ID | 146-22-5 |
| RxCUI | — |
| ChEMBL ID | CHEMBL13209 |
| ChEBI ID | 7581 |
| PubChem CID | 4506 |
| DrugBank | DB01595 |
| UNII ID | 9CLV70W7HS (ChemIDplus, GSRS) |
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Safety
Black-box Warning
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Adverse Events
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3,188 adverse events reported
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