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Drug ReportsNimotuzumab
Nimotuzumab
Nimotuzumab is an antibody pharmaceutical. It is currently being investigated in clinical studies. It is known to target epidermal growth factor receptor.
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Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
No data
Clinical
Clinical Trials
153 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
CarcinomaD002277C80.0135121451
Squamous cell carcinomaD00229412261330
Nasopharyngeal carcinomaD00007727411371123
Nasopharyngeal neoplasmsD0093031106118
Pancreatic neoplasmsD010190EFO_0003860C251131215
Head and neck neoplasmsD0062582215
Premature obstetric laborD007752O6011
Premature birthD047928EFO_0003917O6011
Acute coronary syndromeD054058EFO_000567211
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Esophageal squamous cell carcinomaD000077277115417
Esophageal neoplasmsD004938C15213317
Uterine cervical neoplasmsD00258319312
Squamous cell carcinoma of head and neckD00007719562311
NeoplasmsD009369C80342110
ChemoradiotherapyD059248426
AdenocarcinomaD0002301526
Stomach neoplasmsD013274EFO_0003897C16415
Colorectal neoplasmsD0151792415
ImmunotherapyD007167325
Show 16 more
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Lung neoplasmsD008175C34.9059213
Non-small-cell lung carcinomaD00228947211
Squamous cell neoplasmsD018307144
Oropharyngeal neoplasmsD00995922
Neoplasm metastasisD009362EFO_000970822
Adenosquamous carcinomaD01819622
Drug therapyD00435822
Breast neoplasmsD001943EFO_0003869C5011
Rectal neoplasmsD01200411
Hypopharyngeal neoplasmsD007012C1311
Show 14 more
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Adoptive transferD01926411
Antibody-dependent cell cytotoxicityD00092011
Cellular immunityD00711111
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
DengueD003715A9011
Healthy volunteers/patients11
Heart diseasesD006331EFO_0003777I51.911
Down syndromeD004314EFO_0001064Q9011
DyssomniasD02092011
ParasomniasD020447G47.511
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameNimotuzumab
INNnimotuzumab
Description
Nimotuzumab (humanized mab)
Classification
Antibody
Drug classmonoclonal antibodies
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
>3GKW:H|Heavy chain of the antibody Nimotuzumab QVQLQQSGAEVKKPGSSVKVSCKASGYTFTNYYIYWVRQAPGQGLEWIGGINPTSGGSNFNEKFKTRVTITADESSTTAY MELSSLRSEDTAFYFCTRQGLWFDSDGRGFDFWGQGTTVTVSSASTKGPSVFPLAPSSKSTSGGTAALGCLVKDYFPEPV TVSWNSGALTSGVHTFPAVLQSSGLYSLSSVVTVPSSSLGTQTYICNVNHKPSNTKVDKKVP >3GKW:L|Light chain of the antibody Nimotuzumab DIQMTQSPSSLSASVGDRVTITCRSSQNIVHSNGNTYLDWYQQTPGKAPKLLIYKVSNRFSGVPSRFSGSGSGTDFTFTI SSLQPEDIATYYCFQYSHVPWTFGQGTKLQITREVAAPSVFIFPPSDEQLKSGTASVVCLLNNFYPREAKVQWKVDNALQ SGNSQESVTEQDSKDSTYSLSSTLTLSKADYEKHKVYACEVTHQGLSSPVTKSFNRGEC
Identifiers
PDB3GKW
CAS-ID
RxCUI
ChEMBL IDCHEMBL2108359
ChEBI ID
PubChem CID
DrugBank
UNII ID6NS400BXKH (ChemIDplus, GSRS)
Target
Agency Approved
No data
Alternate
EGFR
EGFR
Organism
Homo sapiens
Gene name
EGFR
Gene synonyms
ERBB, ERBB1, HER1
NCBI Gene ID
Protein name
epidermal growth factor receptor
Protein synonyms
avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, cell growth inhibiting protein 40, cell proliferation-inducing protein 61, EGFR vIII, epidermal growth factor receptor tyrosine kinase domain, erb-b2 receptor tyrosine kinase 1, Proto-oncogene c-ErbB-1, Receptor tyrosine-protein kinase erbB-1
Uniprot ID
Mouse ortholog
Egfr (13649)
epidermal growth factor receptor (Q01279)
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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64 adverse events reported
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