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Drug ReportsNifurtimox
Nifurtimox
Lampit (nifurtimox) is a small molecule pharmaceutical. Nifurtimox was first approved as Lampit on 2020-08-06.
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FDA Novel Drug Approvals 2020
Events Timeline
Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
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FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
Lampit
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Nifurtimox
Tradename
Company
Number
Date
Products
LAMPITBayerN-213464 RX2020-08-06
2 products, RLD, RS
Labels
FDA
EMA
Brand Name
Status
Last Update
lampitNew Drug Application2024-12-10
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
Expiration
Code
NIFURTIMOX, LAMPIT, BAYER HEALTHCARE
2027-08-06ODE-319
2025-08-06NCE
Patent Expiration
No data
ATC Codes
P: Antiparasitic products, insecticides and repellents
— P01: Antiprotozoals
— P01C: Agents against leishmaniasis and trypanosomiasis
— P01CC: Nitrofuran derivatives, antiprotozoal drugs
— P01CC01: Nifurtimox
HCPCS
No data
Clinical
Clinical Trials
19 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
African trypanosomiasisD014353—B56—241—5
TrypanosomiasisD014352DOID_10113B57.2—231—4
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Chagas diseaseD014355EFO_0008559B57422—411
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
NeuroblastomaD009447EFO_0000621—11———2
InfectionsD007239EFO_0000544——1———1
MedulloblastomaD008527———1———1
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Therapeutic equivalencyD013810——1————1
RecurrenceD012008——1————1
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
LactationD007774——————11
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameNifurtimox
INNnifurtimox
Description
Nifurtimox is a nitrofuran antibiotic.
Classification
Small molecule
Drug class5-nitrofuran derivatives
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
CC1CS(=O)(=O)CCN1/N=C/c1ccc([N+](=O)[O-])o1
Identifiers
PDB—
CAS-ID23256-30-6
RxCUI—
ChEMBL IDCHEMBL290960
ChEBI ID7566
PubChem CID6842999
DrugBankDB11820
UNII IDM84I3K7C2O (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 3,203 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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47 adverse events reported
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