Nifurtimox
Lampit (nifurtimox) is a small molecule pharmaceutical. Nifurtimox was first approved as Lampit on 2020-08-06.
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FDA approval date
EMA approval date
Patent expiration date
Study first post date
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Start date
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Results first post date
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Commercial
Therapeutic Areas
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Trade Name
FDA
EMA
Lampit
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| lampit | New Drug Application | 2024-12-10 |
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
Expiration | Code | ||
|---|---|---|---|
NIFURTIMOX, LAMPIT, BAYER HEALTHCARE | |||
| 2027-08-06 | ODE-319 | ||
| 2025-08-06 | NCE | ||
Patent Expiration
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HCPCS
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Clinical
Clinical Trials
19 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Chagas disease | D014355 | EFO_0008559 | B57 | 4 | — | 1 | — | 2 | 7 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neuroblastoma | D009447 | EFO_0000621 | — | — | 1 | — | — | — | 1 |
| Medulloblastoma | D008527 | — | — | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Therapeutic equivalency | D013810 | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Nifurtimox |
| INN | nifurtimox |
| Description | Nifurtimox is a nitrofuran antibiotic. |
| Classification | Small molecule |
| Drug class | 5-nitrofuran derivatives |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC1CS(=O)(=O)CCN1/N=C/c1ccc([N+](=O)[O-])o1 |
Identifiers
| PDB | — |
| CAS-ID | 23256-30-6 |
| RxCUI | — |
| ChEMBL ID | CHEMBL290960 |
| ChEBI ID | 7566 |
| PubChem CID | 6842999 |
| DrugBank | DB11820 |
| UNII ID | M84I3K7C2O (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 3,223 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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47 adverse events reported
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