Therapeutic Area | MeSH |
---|---|
cardiovascular diseases | D002318 |
nutritional and metabolic diseases | D009750 |
Brand Name | Status | Last Update |
---|---|---|
011010 niacinamide 4% / tretinoin 0.025% | unapproved drug other | 2020-07-02 |
011013 niacinamide 4% / tretinoin 0.025% | unapproved drug other | 2020-07-02 |
011020 niacinamide 4% / tretinoin 0.05% | unapproved drug other | 2020-07-02 |
011021 niacinamide 4% / tretinoin 0.05% | unapproved drug other | 2020-07-02 |
011054 niacinamide 4% / spironolactone 5% | unapproved drug other | 2020-07-02 |
011218 niacinamide 2% / spironolactone 5% / tretinoin 0.025% | unapproved drug other | 2020-07-02 |
011220 niacinamide 2% / spironolactone 5% / tretinoin 0.05% | unapproved drug other | 2020-07-02 |
011312 niacinamide 4% / tazarotene 0.05% | unapproved drug other | 2020-07-02 |
011503 dapsone 6% / niacinamide 2% / spironolactone 5% | unapproved drug other | 2020-07-02 |
011504 dapsone 8.5% / niacinamide 4% | unapproved drug other | 2020-07-02 |
Indication | Ontology | MeSH | ICD-10 |
---|---|---|---|
hypercholesterolemia | — | D006937 | — |
hypertriglyceridemia | EFO_0004211 | D015228 | — |
peripheral vascular diseases | EFO_0003875 | D016491 | I73.9 |
pellagra | — | D010383 | — |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Carcinoma | D002277 | — | C80.0 | 74 | 150 | 67 | 9 | 42 | 302 |
Hepatocellular carcinoma | D006528 | — | C22.0 | 66 | 111 | 59 | 10 | 36 | 243 |
Liver neoplasms | D008113 | EFO_1001513 | C22.0 | 71 | 110 | 47 | 10 | 32 | 232 |
Neoplasms | D009369 | — | C80 | 60 | 26 | 7 | 1 | 7 | 93 |
Renal cell carcinoma | D002292 | EFO_0000376 | — | 17 | 44 | 16 | 1 | 20 | 92 |
Dyslipidemias | D050171 | — | — | 6 | 5 | 13 | 14 | 7 | 45 |
Healthy volunteers/patients | — | — | — | 24 | 4 | — | 1 | 14 | 43 |
Hypercholesterolemia | D006937 | — | — | 4 | 2 | 17 | 3 | 6 | 32 |
Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | 4 | 7 | 8 | 3 | 6 | 27 |
Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | 7 | 7 | 6 | 3 | 5 | 26 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Leukemia | D007938 | — | C95 | 21 | 26 | 5 | — | 5 | 46 |
Recurrence | D012008 | — | — | 14 | 32 | 2 | — | 2 | 46 |
Myeloid leukemia acute | D015470 | — | C92.0 | 21 | 19 | 3 | — | 4 | 40 |
Myeloid leukemia | D007951 | — | C92 | 16 | 20 | 3 | — | 4 | 36 |
Lung neoplasms | D008175 | — | C34.90 | 11 | 24 | 4 | — | — | 36 |
Non-small-cell lung carcinoma | D002289 | — | — | 11 | 19 | 5 | — | 1 | 32 |
Breast neoplasms | D001943 | EFO_0003869 | C50 | 9 | 23 | 1 | — | 2 | 30 |
Melanoma | D008545 | — | — | 10 | 17 | 2 | — | — | 27 |
Thyroid diseases | D013959 | — | E00-E07 | — | 18 | 3 | — | 2 | 21 |
Kidney neoplasms | D007680 | EFO_0003865 | C64 | 7 | 8 | 3 | — | 3 | 20 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Sarcoma | D012509 | — | — | 7 | 11 | — | — | — | 16 |
Prostatic neoplasms | D011471 | — | C61 | 6 | 10 | — | — | 1 | 15 |
Colorectal neoplasms | D015179 | — | — | 5 | 10 | — | — | 2 | 15 |
Glioblastoma | D005909 | EFO_0000515 | — | 7 | 10 | — | — | 1 | 14 |
Myelodysplastic syndromes | D009190 | — | D46 | 7 | 9 | — | — | — | 13 |
Inflammation | D007249 | MP_0001845 | — | 3 | 3 | — | — | 8 | 13 |
Precursor cell lymphoblastic leukemia-lymphoma | D054198 | — | C91.0 | 7 | 5 | — | — | — | 11 |
Brain neoplasms | D001932 | EFO_0003833 | C71 | 8 | 5 | — | — | 1 | 11 |
Lymphoma | D008223 | — | C85.9 | 8 | 4 | — | — | — | 10 |
Lymphoid leukemia | D007945 | — | C91 | 6 | 5 | — | — | — | 10 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Metabolic diseases | D008659 | EFO_0000589 | E88.9 | 4 | — | — | — | 5 | 9 |
Hematologic neoplasms | D019337 | — | — | 3 | — | — | — | 1 | 4 |
Pharmacokinetics | D010599 | — | — | 3 | — | — | — | 1 | 4 |
Abdominal obesity | D056128 | — | — | 1 | — | — | — | 2 | 3 |
Glucose intolerance | D018149 | HP_0000833 | R73.03 | 1 | — | — | — | 2 | 3 |
Prediabetic state | D011236 | EFO_1001121 | R73.03 | 1 | — | — | — | 2 | 3 |
Megakaryoblastic leukemia acute | D007947 | — | C94.2 | 3 | — | — | — | — | 3 |
Myelomonocytic leukemia acute | D015479 | — | C92.5 | 3 | — | — | — | — | 3 |
Basophilic leukemia acute | D015471 | — | C94.8 | 3 | — | — | — | — | 3 |
Erythroblastic leukemia acute | D004915 | EFO_1001257 | C94.0 | 3 | — | — | — | — | 3 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Dermatitis | D003872 | — | L30.9 | — | — | — | — | 4 | 4 |
Healthy aging | D000073656 | — | — | — | — | — | — | 4 | 4 |
Diet therapy | D004035 | — | — | — | — | — | — | 3 | 3 |
Constipation | D003248 | — | K59.0 | — | — | — | — | 3 | 3 |
Congenital heart defects | D006330 | — | Q24.9 | — | — | — | — | 3 | 3 |
Respiratory tract infections | D012141 | — | J06.9 | — | — | — | — | 3 | 3 |
Cognition | D003071 | EFO_0003925 | — | — | — | — | — | 3 | 3 |
Exercise | D015444 | EFO_0000483 | — | — | — | — | — | 3 | 3 |
Overweight | D050177 | — | E66.3 | — | — | — | — | 3 | 3 |
Heart valve diseases | D006349 | EFO_0009551 | I08 | — | — | — | — | 3 | 3 |
Drug common name | Niacin |
INN | nicotinic acid |
Description | Nicotinic acid is a pyridinemonocarboxylic acid that is pyridine in which the hydrogen at position 3 is replaced by a carboxy group. It has a role as an antidote, an antilipemic drug, a vasodilator agent, a metabolite, an EC 3.5.1.19 (nicotinamidase) inhibitor, an Escherichia coli metabolite, a mouse metabolite, a human urinary metabolite and a plant metabolite. It is a vitamin B3, a pyridinemonocarboxylic acid and a pyridine alkaloid. It is a conjugate acid of a nicotinate. |
Classification | Small molecule |
Drug class | — |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | O=C(O)c1cccnc1 |
PDB | — |
CAS-ID | 59-67-6 |
RxCUI | — |
ChEMBL ID | CHEMBL573 |
ChEBI ID | 15940 |
PubChem CID | 938 |
DrugBank | DB00627 |
UNII ID | 2679MF687A (ChemIDplus, GSRS) |