Neramexane
Neramexane is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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Clinical
Clinical Trials
16 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Tinnitus | D014012 | HP_0000360 | H93.1 | — | 1 | 4 | — | — | 5 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Congenital nystagmus | D020417 | EFO_0007217 | H55.01 | — | 2 | — | — | — | 2 |
| Pathologic nystagmus | D009759 | HP_0000666 | H55.0 | — | 2 | — | — | — | 2 |
| Multiple sclerosis | D009103 | EFO_0003885 | G35 | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 7 | — | — | — | — | 7 |
Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Neramexane |
| INN | neramexane |
| Description | Neramexane is a drug related to memantine, which acts as an NMDA antagonist and has neuroprotective effects. It is being developed for various possible applications, including treatment of tinnitus, Alzheimer's disease, drug addiction and as an analgesic. Animal studies have also suggested antidepressant and nootropic actions, so there are a wide range of potential applications this drug may be used for. It also acts as a nicotinic acetylcholine receptor antagonist.
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| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC1(C)CC(C)(C)CC(C)(N)C1 |
Identifiers
| PDB | — |
| CAS-ID | 219810-59-0 |
| RxCUI | — |
| ChEMBL ID | CHEMBL2110954 |
| ChEBI ID | — |
| PubChem CID | 6433106 |
| DrugBank | — |
| UNII ID | 856DX0KJ84 (ChemIDplus, GSRS) |
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Safety
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Adverse Events
0 adverse events reported
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