Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Cataract | D002386 | EFO_0001059 | H26.9 | — | 5 | 8 | 11 | 2 | 26 |
Macular edema | D008269 | — | — | — | 4 | 1 | 7 | 1 | 13 |
Inflammation | D007249 | MP_0001845 | — | — | 1 | 4 | 4 | 1 | 10 |
Edema | D004487 | — | R60.9 | — | 2 | 1 | 5 | — | 8 |
Pain | D010146 | EFO_0003843 | R52 | — | 1 | — | 1 | 2 | 4 |
Intraocular pressure | D007429 | — | — | — | — | — | 2 | — | 2 |
Myopia | D009216 | EFO_0003927 | H52.1 | — | — | — | 1 | 1 | 2 |
Cataract extraction | D002387 | — | — | — | — | — | 2 | — | 2 |
Retinal vein occlusion | D012170 | EFO_1001157 | H34.81 | — | — | — | 1 | — | 1 |
Macular degeneration | D008268 | EFO_0001365 | H35.30 | — | — | — | 1 | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Diabetic retinopathy | D003930 | EFO_0003770 | — | — | 2 | 3 | — | — | 5 |
Retinal diseases | D012164 | — | H35.9 | — | 2 | 2 | — | — | 4 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Miosis | D015877 | — | H57.03 | — | 1 | — | — | — | 1 |
Phacoemulsification | D018918 | — | — | — | 1 | — | — | — | 1 |
Fuchs' endothelial dystrophy | D005642 | EFO_0003946 | H18.51 | — | 1 | — | — | — | 1 |
Bacterial conjunctivitis | D003234 | EFO_1000829 | H10.0 | — | 1 | — | — | — | 1 |
Conjunctivitis | D003231 | — | H10 | — | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Glaucoma | D005901 | EFO_0000516 | H40 | — | — | — | — | 1 | 1 |
Angle-closure glaucoma | D015812 | — | — | — | — | — | — | 1 | 1 |
Pain management | D059408 | — | — | — | — | — | — | 1 | 1 |
Postoperative care | D011182 | — | — | — | — | — | — | 1 | 1 |
Papilledema | D010211 | EFO_1001074 | H35.81 | — | — | — | — | 1 | 1 |
Central serous chorioretinopathy | D056833 | — | H35.71 | — | — | — | — | 1 | 1 |
Drug common name | Nepafenac |
INN | nepafenac |
Description | Nepafenac is a monocarboxylic acid amide that is amfenac in which the carboxylic acid group has been converted into the corresponding carboxamide. It is a prodrug for amfenac, used in eye drops to treat pain and inflammation following cataract surgery. It has a role as a prodrug, a cyclooxygenase 2 inhibitor, a cyclooxygenase 1 inhibitor, a non-steroidal anti-inflammatory drug and a non-narcotic analgesic. |
Classification | Small molecule |
Drug class | anti-inflammatory agents (acetic acid derivatives) |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | NC(=O)Cc1cccc(C(=O)c2ccccc2)c1N |
PDB | — |
CAS-ID | 78281-72-8 |
RxCUI | — |
ChEMBL ID | CHEMBL1021 |
ChEBI ID | 75922 |
PubChem CID | 151075 |
DrugBank | DB06802 |
UNII ID | 0J9L7J6V8C (ChemIDplus, GSRS) |