Viracept(nelfinavir)
Viracept (nelfinavir) is a small molecule pharmaceutical. Nelfinavir was first approved as Viracept on 1997-03-14. It is used to treat acquired immunodeficiency syndrome in the USA. It has been approved in Europe to treat HIV infections.
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Commercial
Therapeutic Areas
Therapeutic Area | MeSH |
|---|---|
| infections | D007239 |
| urogenital diseases | D000091642 |
| immune system diseases | D007154 |
Trade Name
FDA
EMA
Viracept (discontinued: Viracept)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Nelfinavir mesylate
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| VIRACEPT | Agouron Pharmaceuticals | N-020779 RX | 1997-03-14 | 1 products, RLD, RS |
| VIRACEPT | Agouron Pharmaceuticals | N-021503 RX | 2003-04-30 | 1 products, RLD, RS |
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Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| viracept | New Drug Application | 2024-03-22 |
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| acquired immunodeficiency syndrome | EFO_0000765 | D000163 | B20 |
Agency Specific
FDA
EMA
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Patent Expiration
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HCPCS
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Clinical
Clinical Trials
148 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hiv infections | D015658 | EFO_0000764 | B20 | 1 | 9 | 1 | 1 | 4 | 16 |
Indications Phases 3
No data
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Infections | D007239 | EFO_0000544 | — | — | 3 | — | — | 1 | 4 |
| Communicable diseases | D003141 | — | — | — | 1 | — | — | 1 | 2 |
| Hiv seropositivity | D006679 | — | — | — | 1 | — | — | — | 1 |
| Sarcoma | D012509 | — | — | — | 1 | — | — | — | 1 |
| Kaposi sarcoma | D012514 | — | C46 | — | 1 | — | — | — | 1 |
| Mycobacterium avium-intracellulare infection | D015270 | EFO_0007386 | — | — | 1 | — | — | — | 1 |
| Mycobacterium infections | D009164 | — | A31.9 | — | 1 | — | — | — | 1 |
| Opportunistic infections | D009894 | — | — | — | 1 | — | — | — | 1 |
| Cytomegalovirus retinitis | D017726 | EFO_1001302 | — | — | 1 | — | — | — | 1 |
| Retinitis | D012173 | — | H30.9 | — | 1 | — | — | — | 1 |
Indications Phases 1
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Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Nelfinavir |
| INN | nelfinavir |
| Description | Nelfinavir is an aryl sulfide that is used (as its mesylate salt) for treatment of HIV and also exhibits some anticancer properties. It has a role as a HIV protease inhibitor and an antineoplastic agent. It is a member of benzamides, a member of phenols, an aryl sulfide, a secondary alcohol, a tertiary amino compound and an organic heterobicyclic compound. It is a conjugate base of a nelfinavir(1+). |
| Classification | Small molecule |
| Drug class | antivirals: HIV protease inhibitors (saquinavir type) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | Cc1c(O)cccc1C(=O)N[C@@H](CSc1ccccc1)[C@H](O)CN1C[C@H]2CCCC[C@H]2C[C@H]1C(=O)NC(C)(C)C |
Identifiers
| PDB | — |
| CAS-ID | 159989-64-7 |
| RxCUI | — |
| ChEMBL ID | CHEMBL584 |
| ChEBI ID | 7496 |
| PubChem CID | 64143 |
| DrugBank | DB00220 |
| UNII ID | HO3OGH5D7I (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Estimated US medical usage
Nelfinavir
Total medical expenditures per year (USD, in millions)
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Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 8,238 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
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3,829 adverse events reported
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