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Drug ReportsNedocromil
Nedocromil
Alocril, Tilade (nedocromil) is a small molecule pharmaceutical. Nedocromil was first approved as Tilade on 1992-12-30. It is used to treat allergic conjunctivitis and pruritus in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
eye diseasesD005128
skin and connective tissue diseasesD017437
immune system diseasesD007154
signs and symptoms pathological conditionsD013568
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Nedocromil sodium
Tradename
Company
Number
Date
Products
ALOCRILAllerganN-021009 DISCN1999-12-08
1 products, RLD
TILADEKing PharmaceuticalsN-019660 DISCN1992-12-30
1 products
TILADESanofiN-020750 DISCN1997-10-01
1 products
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Labels
FDA
EMA
Brand Name
Status
Last Update
alocrilNew Drug Application2018-07-17
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
R: Respiratory system drugs
— R01: Nasal preparations
— R01A: Decongestants and other nasal preparations for topical use
— R01AC: Antiallergic nasal preparations for topical use, excl. corticosteroids
— R01AC07: Nedocromil
— R03: Drugs for obstructive airway diseases
— R03B: Other drugs for obstructive airway diseases, inhalants in atc
— R03BC: Antiallergic inhalants for obstructive airway diseases, excl. corticosteroids
— R03BC03: Nedocromil
S: Sensory organ drugs
— S01: Ophthalmologicals
— S01G: Decongestants and antiallergics
— S01GX: Other antiallergics in atc
— S01GX04: Nedocromil
HCPCS
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Clinical
Clinical Trials
5 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
AsthmaD001249EFO_0000270J451—2—14
Lung diseasesD008171HP_0002088J98.4——1—12
Indications Phases 2
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Indications Phases 1
No data
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
BurnsD002056—T30.0————11
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameNedocromil
INNnedocromil
Description
Nedocromil is a dicarboxylic acid and an organic heterotricyclic compound. It has a role as a non-steroidal anti-inflammatory drug, an anti-asthmatic drug and an anti-allergic agent. It is a conjugate acid of a nedocromil(2-).
Classification
Small molecule
Drug classantiallergics (cromoglicic acid derivatives)
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Structure (InChI/SMILES or Protein Sequence)
CCCc1c2oc(C(=O)O)cc(=O)c2cc2c(=O)cc(C(=O)O)n(CC)c12
Identifiers
PDB—
CAS-ID69049-73-6
RxCUI—
ChEMBL IDCHEMBL746
ChEBI ID7492
PubChem CID50294
DrugBankDB00716
UNII ID0B535E0BN0 (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
Revenue by drug
$
€
£
â‚£
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Estimated US medical usage
Nedocromil
Total medical expenditures per year (USD, in millions)
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Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 1,671 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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54 adverse events reported
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