Starlix(nateglinide)
Nateglinide, Starlix, Trazec (nateglinide) is a small molecule pharmaceutical. Nateglinide was first approved as Starlix on 2000-12-22. It is used to treat type 2 diabetes mellitus in the USA. It has been approved in Europe to treat type 2 diabetes mellitus.
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Commercial
Therapeutic Areas
Therapeutic Area | MeSH |
|---|---|
| nutritional and metabolic diseases | D009750 |
| endocrine system diseases | D004700 |
Trade Name
FDA
EMA
Nateglinide (discontinued: Nateglinide, Starlix)
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| nateglinide | ANDA | 2025-01-07 |
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| type 2 diabetes mellitus | EFO_0001360 | D003924 | E11 |
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
HCPCS
No data
Clinical
No data
Drug
General
| Drug common name | Nateglinide |
| INN | nateglinide |
| Description | (2S)-2-[[oxo-(4-propan-2-ylcyclohexyl)methyl]amino]-3-phenylpropanoic acid is a phenylalanine derivative. |
| Classification | Small molecule |
| Drug class | antidiabetic, sodium glucose co-transporter 2 (SGLT2) inhibitors, not phlorozin derivatives |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CC(C)[C@H]1CC[C@H](C(=O)N[C@H](Cc2ccccc2)C(=O)O)CC1 |
Identifiers
| PDB | — |
| CAS-ID | 105816-04-4 |
| RxCUI | — |
| ChEMBL ID | CHEMBL783 |
| ChEBI ID | 31897 |
| PubChem CID | 60026 |
| DrugBank | DB00731 |
| UNII ID | 41X3PWK4O2 (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Estimated US medical usage
Nateglinide
Total medical expenditures per year (USD, in millions)
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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