Nacubactam
Nacubactam is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Events
FDA approval date
EMA approval date
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Study first post date
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Start date
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Commercial
No data
Clinical
Clinical Trials
6 clinical trials
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Indications Phases 4
No data
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Infections | D007239 | EFO_0000544 | — | 1 | — | 2 | — | — | 3 |
| Urinary tract infections | D014552 | EFO_0003103 | N39.0 | 1 | — | 2 | — | — | 3 |
| Communicable diseases | D003141 | — | — | 1 | — | 2 | — | — | 3 |
| Pyelonephritis | D011704 | EFO_1001141 | N10-N16 | — | — | 2 | — | — | 2 |
| Ventilator-associated pneumonia | D053717 | EFO_1001865 | J95.851 | — | — | 1 | — | — | 1 |
| Iatrogenic disease | D007049 | — | — | — | — | 1 | — | — | 1 |
| Pneumonia | D011014 | EFO_0003106 | — | — | — | 1 | — | — | 1 |
| Intraabdominal infections | D059413 | — | — | — | — | 1 | — | — | 1 |
| Bacterial pneumonia | D018410 | EFO_1001272 | J15.9 | — | — | 1 | — | — | 1 |
Indications Phases 2
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Healthy volunteers/patients | — | — | — | 1 | — | — | — | — | 1 |
| Bacterial infections | D001424 | — | A49 | 1 | — | — | — | — | 1 |
| Gram-negative bacterial infections | D016905 | — | — | 1 | — | — | — | — | 1 |
| Renal insufficiency | D051437 | HP_0000083 | N19 | 1 | — | — | — | — | 1 |
Indications Without Phase
No data
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Nacubactam |
| INN | nacubactam |
| Description | Nacubactam is a small molecule pharmaceutical. It is currently being investigated in clinical studies. |
| Classification | Small molecule |
| Drug class | beta-lactamase inhibitors |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | NCCONC(=O)[C@@H]1CC[C@@H]2CN1C(=O)N2OS(=O)(=O)O |
Identifiers
| PDB | — |
| CAS-ID | 1452458-86-4 |
| RxCUI | — |
| ChEMBL ID | CHEMBL3989959 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | 832O37V7MZ (ChemIDplus, GSRS) |
Target
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Variants
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Financial
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Trends
PubMed Central
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Additional graphs summarizing 190 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
0 adverse events reported
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