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Drug ReportsMoxidectin
Moxidectin
Moxidectin (moxidectin) is a small molecule pharmaceutical. Moxidectin was first approved as Moxidectin on 2018-06-13. It is used to treat ocular onchocerciasis in the USA.
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Drug
Target
Variants
Financial
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Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
eye diseasesD005128
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Moxidectin
Tradename
Company
Number
Date
Products
MOXIDECTINMedicines Development for Global HealthN-210867 RX2018-06-13
1 products, RLD, RS
Labels
FDA
EMA
Brand Name
Status
Last Update
moxidectinNew Drug Application2024-05-02
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
ocular onchocerciasisEFO_0007398D015827B73
Agency Specific
FDA
EMA
Expiration
Code
MOXIDECTIN, MOXIDECTIN, MDGH
2025-06-13ODE-193
Patent Expiration
No data
ATC Codes
P: Antiparasitic products, insecticides and repellents
— P02: Anthelmintics
— P02C: Antinematodal agents
— P02CX: Other antinematodals in atc
— P02CX03: Moxidectin
HCPCS
No data
Clinical
Clinical Trials
24 clinical trials
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Indications Phases 4
No data
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
OnchocerciasisD009855EFO_0007402B73143——8
InfectionsD007239EFO_0000544—233——7
TrichuriasisD014257EFO_0007524——23——4
AscariasisD001196EFO_0007154B77—13——3
Hookworm infectionsD006725EFO_0007314B76—13——3
AncylostomiasisD000724EFO_0007145B76.0—13——3
Filarial elephantiasisD004605EFO_0007272B74.0——2——2
FilariasisD005368—B74——2——2
ElephantiasisD004604EFO_0004711———2——2
StrongyloidiasisD013322EFO_0007501B78—11——2
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Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Ocular onchocerciasisD015827EFO_0007398B73—2———2
ScabiesD012532—B86—2———2
LoiasisD008118—B74.3—1———1
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients———1————1
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
MalariaD008288EFO_0001068B54————33
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameMoxidectin
INNmoxidectin
Description
Moxidectin is a milbemycin.
Classification
Small molecule
Drug classantiparasitics (ivermectin type)
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
CO/N=C1\C[C@]2(C[C@@H]3C[C@@H](C/C=C(\C)C[C@@H](C)/C=C/C=C4\CO[C@@H]5[C@H](O)C(C)=C[C@@H](C(=O)O3)[C@]45O)O2)O[C@H](/C(C)=C/C(C)C)[C@H]1C
Identifiers
PDB—
CAS-ID113507-06-5
RxCUI—
ChEMBL IDCHEMBL2104415
ChEBI ID—
PubChem CID9832912
DrugBankDB11431
UNII IDNGU5H31YO9 (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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2 adverse events reported
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