Mosapride
Mosapride is a small molecule pharmaceutical. It is currently being investigated in clinical studies. It is known to target 5-hydroxytryptamine receptor 4.
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Dyspepsia | D004415 | EFO_0008533 | K30 | 1 | — | — | — | — | 1 |
| Gastritis | D005756 | EFO_0000217 | K29.7 | 1 | — | — | — | — | 1 |
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Drug
General
| Drug common name | Mosapride |
| INN | mosapride |
| Description | Mosapride is a racemate comprising equimolar amounts of (R)- and (S)-mosapride. It is a gastroprokinetic agent which acts on 5-hydroxytryptamine type 4 (5-HT4) receptors in the gastrointestinal plexus, consequently increasing the release of acetylcholine and hence enhancing gastrointestinal motility and gastric emptying. It has a role as a gastrointestinal drug and a serotonergic agonist. It contains a (R)-mosapride and a (S)-mosapride. |
| Classification | Small molecule |
| Drug class | sulpride derivatives and analogs |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | CCOc1cc(N)c(Cl)cc1C(=O)NCC1CN(Cc2ccc(F)cc2)CCO1 |
Identifiers
| PDB | — |
| CAS-ID | 112885-41-3 |
| RxCUI | — |
| ChEMBL ID | CHEMBL60889 |
| ChEBI ID | — |
| PubChem CID | 119584 |
| DrugBank | DB11675 |
| UNII ID | I8MFJ1C0BY (ChemIDplus, GSRS) |
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HTR4
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278 adverse events reported
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