Molgramostim
Molgramostim is a protein pharmaceutical. It is currently being investigated in clinical studies.
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2254 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Leukemia | D007938 | — | C95 | 101 | 202 | 48 | 10 | 28 | 338 |
| Lymphoma | D008223 | — | C85.9 | 78 | 208 | 41 | 12 | 26 | 331 |
| Myeloid leukemia acute | D015470 | — | C92.0 | 76 | 137 | 35 | 4 | 15 | 235 |
| Multiple myeloma | D009101 | — | C90.0 | 58 | 115 | 22 | 3 | 17 | 193 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 52 | 93 | 33 | 12 | 7 | 175 |
| Myelodysplastic syndromes | D009190 | — | D46 | 61 | 105 | 17 | 3 | 14 | 170 |
| Neoplasms | D009369 | — | C80 | 79 | 78 | 16 | 4 | 13 | 168 |
| Non-hodgkin lymphoma | D008228 | — | C85.9 | 45 | 103 | 23 | 4 | 12 | 167 |
| Precursor cell lymphoblastic leukemia-lymphoma | D054198 | — | C91.0 | 44 | 87 | 16 | 9 | 12 | 148 |
| Myeloid leukemia | D007951 | — | C92 | 34 | 71 | 20 | 2 | 8 | 119 |
Show 63 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hodgkin disease | D006689 | — | C81 | 23 | 57 | 12 | — | 4 | 87 |
| Large b-cell lymphoma diffuse | D016403 | — | C83.3 | 25 | 45 | 12 | — | 5 | 77 |
| B-cell chronic lymphocytic leukemia | D015451 | — | C91.1 | 28 | 45 | 4 | — | 7 | 76 |
| Sarcoma | D012509 | — | — | 25 | 46 | 10 | — | 3 | 75 |
| Bcr-abl positive chronic myelogenous leukemia | D015464 | EFO_0000340 | — | 16 | 47 | 4 | — | 3 | 63 |
| Myeloproliferative disorders | D009196 | — | D47.1 | 23 | 36 | 3 | — | 8 | 63 |
| Follicular lymphoma | D008224 | — | C82 | 23 | 32 | 6 | — | 5 | 59 |
| Mantle-cell lymphoma | D020522 | — | C83.1 | 21 | 35 | 3 | — | 5 | 58 |
| Central nervous system neoplasms | D016543 | — | — | 18 | 33 | 4 | — | 2 | 53 |
| Lung neoplasms | D008175 | — | C34.90 | 11 | 33 | 4 | — | 8 | 52 |
Show 167 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Colorectal neoplasms | D015179 | — | — | 13 | 19 | — | — | 3 | 28 |
| Fallopian tube neoplasms | D005185 | — | — | 10 | 10 | — | — | 1 | 19 |
| Glioma | D005910 | EFO_0000520 | — | 13 | 8 | — | — | — | 19 |
| Blast crisis | D001752 | — | — | 9 | 7 | — | — | 1 | 16 |
| Liver neoplasms | D008113 | EFO_1001513 | C22.0 | 7 | 10 | — | — | — | 15 |
| Oligodendroglioma | D009837 | EFO_0000631 | — | 11 | 4 | — | — | — | 14 |
| Fanconi anemia | D005199 | Orphanet_84 | D61.03 | 6 | 11 | — | — | 1 | 14 |
| Colonic neoplasms | D003110 | — | C18 | 5 | 8 | — | — | 1 | 11 |
| T-cell lymphoma | D016399 | — | — | 2 | 8 | — | — | 1 | 11 |
| T-cell lymphoma peripheral | D016411 | — | — | 1 | 9 | — | — | 1 | 11 |
Show 225 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hairy cell leukemia | D007943 | — | C91.4 | 3 | — | — | — | 3 | 6 |
| Aids-related complex | D000386 | EFO_0007137 | B20 | 2 | — | — | — | 2 | 4 |
| Pinealoma | D010871 | — | — | 3 | — | — | — | — | 3 |
| Coronary artery disease | D003324 | — | I25.1 | 1 | — | — | — | 2 | 3 |
| Leukopenia | D007970 | EFO_0004233 | D72.819 | 2 | — | — | — | 1 | 3 |
| Basal cell carcinoma | D002280 | — | — | 2 | — | — | — | — | 2 |
| Meningioma | D008579 | EFO_0003098 | D32.9 | 2 | — | — | — | — | 2 |
| Hypertrophic pyloric stenosis | D046248 | — | Q40.0 | 2 | — | — | — | — | 2 |
| Clear cell sarcoma | D018227 | — | — | 2 | — | — | — | — | 2 |
| Vasculitis | D014657 | EFO_0006803 | M31 | 1 | — | — | — | 1 | 2 |
Show 47 more
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Arterial occlusive diseases | D001157 | EFO_0009085 | — | — | — | — | — | 2 | 2 |
| Hemophagocytic lymphohistiocytosis | D051359 | — | D76.1 | — | — | — | — | 2 | 2 |
| Thrombocytopenic purpura idiopathic | D016553 | EFO_0007160 | D69.3 | — | — | — | — | 2 | 2 |
| Brain injuries | D001930 | — | S06.9 | — | — | — | — | 2 | 2 |
| Abnormal karyotype | D059786 | — | — | — | — | — | — | 1 | 1 |
| Lupus nephritis | D008181 | EFO_0005761 | — | — | — | — | — | 1 | 1 |
| Nephritis | D009393 | — | N05 | — | — | — | — | 1 | 1 |
| Chediak-higashi syndrome | D002609 | Orphanet_167 | D72.0 | — | — | — | — | 1 | 1 |
| Arteritis | D001167 | EFO_0009011 | I77.6 | — | — | — | — | 1 | 1 |
| Iga vasculitis | D011695 | EFO_1000965 | D69.0 | — | — | — | — | 1 | 1 |
Show 35 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Molgramostim |
| INN | molgramostim |
| Description | Molgramostim is a recombinant granulocyte macrophage colony-stimulating factor which functions as an immunostimulator.
|
| Classification | Protein |
| Drug class | colony-stimulating factors: granulocyte macrophage colony-stimulating factors (GM-CSF); colony-stimulating factors: macrophage colony-stimulating factors (M-CSF) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL2109134 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | B321AL142J (ChemIDplus, GSRS) |
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Trends
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Safety
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Adverse Events
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17 adverse events reported
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