Molgramostim
Molgramostim is a protein pharmaceutical. It is currently being investigated in clinical studies.
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Clinical Trials
1257 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Leukemia | D007938 | — | C95 | 66 | 127 | 37 | 4 | 18 | 222 |
| Lymphoma | D008223 | — | C85.9 | 39 | 108 | 18 | 5 | 9 | 166 |
| Myeloid leukemia acute | D015470 | — | C92.0 | 43 | 82 | 23 | 2 | 8 | 138 |
| Myeloid leukemia | D007951 | — | C92 | 42 | 82 | 23 | 1 | 6 | 135 |
| Neoplasms | D009369 | — | C80 | 52 | 56 | 10 | 1 | 9 | 111 |
| Multiple myeloma | D009101 | — | C90.0 | 34 | 56 | 8 | 1 | 7 | 94 |
| Myelodysplastic syndromes | D009190 | — | D46 | 35 | 58 | 10 | 1 | 5 | 92 |
| Plasma cell neoplasms | D054219 | — | — | 31 | 50 | 9 | 1 | 5 | 85 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | 29 | 42 | 14 | 6 | 4 | 84 |
| Melanoma | D008545 | — | — | 28 | 47 | 7 | 1 | 6 | 78 |
Show 46 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Preleukemia | D011289 | — | — | 26 | 44 | 6 | — | 3 | 66 |
| Syndrome | D013577 | — | — | 22 | 36 | 4 | — | 4 | 54 |
| Recurrence | D012008 | — | — | 22 | 26 | 5 | — | — | 46 |
| Sarcoma | D012509 | — | — | 17 | 15 | 8 | — | 1 | 39 |
| Bcr-abl positive chronic myelogenous leukemia | D015464 | EFO_0000340 | — | 10 | 25 | 3 | — | 2 | 37 |
| Lung neoplasms | D008175 | — | C34.90 | 12 | 23 | 1 | — | 4 | 37 |
| Carcinoma | D002277 | — | C80.0 | 13 | 21 | 2 | — | 2 | 35 |
| Hiv infections | D015658 | EFO_0000764 | B20 | 16 | 12 | 2 | — | 7 | 34 |
| Ovarian neoplasms | D010051 | EFO_0003893 | C56 | 14 | 18 | 2 | — | 3 | 33 |
| Hodgkin disease | D006689 | — | C81 | 6 | 20 | 5 | — | 1 | 32 |
Show 124 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Colorectal neoplasms | D015179 | — | — | 11 | 17 | — | — | 1 | 22 |
| Follicular lymphoma | D008224 | — | C82 | 5 | 13 | — | — | — | 16 |
| Mantle-cell lymphoma | D020522 | — | C83.1 | 3 | 13 | — | — | — | 14 |
| Glioma | D005910 | EFO_0000520 | — | 9 | 7 | — | — | — | 13 |
| Pancytopenia | D010198 | — | D61.81 | 4 | 5 | — | — | 4 | 13 |
| Germ cell and embryonal neoplasms | D009373 | — | — | 5 | 5 | — | — | 2 | 12 |
| Myelodysplastic-myeloproliferative diseases | D054437 | — | — | 5 | 8 | — | — | 1 | 12 |
| Fallopian tube neoplasms | D005185 | — | — | 5 | 6 | — | — | 1 | 11 |
| Healthy volunteers/patients | — | — | — | 8 | 1 | — | — | 2 | 11 |
| Liver neoplasms | D008113 | EFO_1001513 | C22.0 | 6 | 5 | — | — | — | 9 |
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Leukopenia | D007970 | EFO_0004233 | D72.819 | 3 | — | — | — | 1 | 4 |
| Clear cell sarcoma | D018227 | — | — | 2 | — | — | — | — | 2 |
| Aids-related complex | D000386 | EFO_0007137 | B20 | 1 | — | — | — | 1 | 2 |
| Diffuse intrinsic pontine glioma | D000080443 | — | — | 2 | — | — | — | — | 2 |
| Virus diseases | D014777 | — | B34 | 2 | — | — | — | — | 2 |
| Myeloid sarcoma | D023981 | — | C92.3 | 1 | — | — | — | — | 1 |
| Primitive neuroectodermal tumors peripheral | D018241 | — | — | 1 | — | — | — | — | 1 |
| Atherosclerosis | D050197 | EFO_0003914 | I25.1 | 1 | — | — | — | — | 1 |
| Chordoma | D002817 | EFO_0000334 | — | 1 | — | — | — | — | 1 |
| Basal cell carcinoma | D002280 | — | — | 1 | — | — | — | — | 1 |
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Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Arterial occlusive diseases | D001157 | EFO_0009085 | — | — | — | — | — | 2 | 2 |
| Brain injuries | D001930 | — | S06.9 | — | — | — | — | 2 | 2 |
| Peritonitis | D010538 | EFO_0008588 | K65 | — | — | — | — | 2 | 2 |
| Intermittent claudication | D007383 | EFO_0003876 | I73.9 | — | — | — | — | 1 | 1 |
| Abnormal karyotype | D059786 | — | — | — | — | — | — | 1 | 1 |
| Lupus nephritis | D008181 | EFO_0005761 | — | — | — | — | — | 1 | 1 |
| Nephritis | D009393 | — | N05 | — | — | — | — | 1 | 1 |
| Hemophagocytic lymphohistiocytosis | D051359 | — | D76.1 | — | — | — | — | 1 | 1 |
| Retinal neoplasms | D019572 | — | C69.2 | — | — | — | — | 1 | 1 |
| Tissue adhesions | D000267 | — | — | — | — | — | — | 1 | 1 |
Show 14 more
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Molgramostim |
| INN | molgramostim |
| Description | Molgramostim is a recombinant granulocyte macrophage colony-stimulating factor which functions as an immunostimulator.
|
| Classification | Protein |
| Drug class | colony-stimulating factors: granulocyte macrophage colony-stimulating factors (GM-CSF); colony-stimulating factors: macrophage colony-stimulating factors (M-CSF) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | — |
| RxCUI | — |
| ChEMBL ID | CHEMBL2109134 |
| ChEBI ID | — |
| PubChem CID | — |
| DrugBank | — |
| UNII ID | B321AL142J (ChemIDplus, GSRS) |
Target
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Trends
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Additional graphs summarizing 495 documents
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Safety
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Adverse Events
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17 adverse events reported
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