Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Fatigue | D005221 | HP_0012378 | R53.83 | 3 | 10 | 7 | 4 | 3 | 25 |
Healthy volunteers/patients | — | — | — | 11 | 1 | — | 1 | 4 | 16 |
Schizophrenia | D012559 | EFO_0000692 | F20 | 3 | 4 | — | 5 | 1 | 12 |
Obstructive sleep apnea | D020181 | EFO_0003918 | G47.33 | — | 1 | 7 | 3 | 1 | 12 |
Sleepiness | D000077260 | — | R40.0 | — | 1 | 4 | 2 | 1 | 7 |
Sleep initiation and maintenance disorders | D007319 | — | F51.01 | — | 2 | — | 2 | 1 | 5 |
Sleep wake disorders | D012893 | — | G47 | — | 1 | 1 | 1 | 1 | 4 |
Psychotic disorders | D011618 | — | F20.81 | 1 | — | — | 3 | — | 4 |
Multiple sclerosis | D009103 | EFO_0003885 | G35 | — | 1 | 2 | 1 | 1 | 4 |
Major depressive disorder | D003865 | EFO_0003761 | F22 | — | 1 | 2 | 1 | — | 4 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Cocaine-related disorders | D019970 | — | F14 | 4 | 15 | 1 | — | 3 | 22 |
Narcolepsy | D009290 | HP_0030050 | G47.4 | 1 | 3 | 11 | — | 4 | 19 |
Neoplasms | D009369 | — | C80 | 1 | 3 | 3 | — | 1 | 8 |
Disorders of excessive somnolence | D006970 | — | G47.1 | — | 2 | 5 | — | 2 | 8 |
Depression | D003863 | — | F33.9 | — | 1 | 4 | — | 1 | 6 |
Sleep apnea syndromes | D012891 | HP_0010535 | G47.3 | 1 | — | 2 | — | 1 | 4 |
Cataplexy | D002385 | HP_0002524 | — | — | — | 2 | — | 1 | 3 |
Attention deficit disorder with hyperactivity | D001289 | EFO_0003888 | F90 | — | 1 | 2 | — | — | 3 |
Circadian rhythm sleep disorders | D020178 | — | G47.2 | — | — | 2 | — | 1 | 3 |
Traumatic brain injuries | D000070642 | — | S06 | — | — | 2 | — | 1 | 3 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Parkinson disease | D010300 | EFO_0002508 | G20 | — | 3 | — | — | 2 | 5 |
Substance-related disorders | D019966 | EFO_0003890 | F13 | 2 | 1 | — | — | 1 | 4 |
Amphetamine-related disorders | D019969 | EFO_0004701 | F15 | 1 | 3 | — | — | — | 4 |
Alcoholism | D000437 | EFO_0003829 | F10.1 | — | 2 | — | — | 1 | 3 |
Opioid-related disorders | D009293 | EFO_0005611 | F11 | — | 1 | — | — | 2 | 3 |
Glioma | D005910 | EFO_0000520 | — | — | 2 | — | — | — | 2 |
Head and neck neoplasms | D006258 | — | — | 2 | 2 | — | — | — | 2 |
Sleep deprivation | D012892 | — | F51.12 | 1 | 1 | — | — | — | 2 |
Central nervous system neoplasms | D016543 | — | — | — | 1 | — | — | 1 | 2 |
Tachycardia | D013610 | HP_0001649 | R00.0 | 1 | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Melanoma | D008545 | — | — | 1 | — | — | — | — | 1 |
Pure autonomic failure | D054970 | — | — | 1 | — | — | — | — | 1 |
Orthostatic hypotension | D007024 | — | I95.1 | 1 | — | — | — | — | 1 |
Humans | D006801 | — | STY/T016 | 1 | — | — | — | — | 1 |
Drug interactions | D004347 | — | — | 1 | — | — | — | — | 1 |
Marijuana abuse | D002189 | EFO_0007191 | F12 | 1 | — | — | — | — | 1 |
Cannabis | D002188 | — | — | 1 | — | — | — | — | 1 |
Neurobehavioral manifestations | D019954 | EFO_0004364 | — | 1 | — | — | — | — | 1 |
Postural orthostatic tachycardia syndrome | D054972 | — | G90.A | 1 | — | — | — | — | 1 |
Mood disorders | D019964 | EFO_0004247 | F30-F39 | 1 | — | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Bcr-abl positive chronic myelogenous leukemia | D015464 | EFO_0000340 | — | — | — | — | — | 1 | 1 |
Relapsing-remitting multiple sclerosis | D020529 | EFO_0003929 | — | — | — | — | — | 1 | 1 |
Glucose metabolism disorders | D044882 | — | — | — | — | — | — | 1 | 1 |
Lung neoplasms | D008175 | HP_0100526 | C34.90 | — | — | — | — | 1 | 1 |
B-cell lymphoma | D016393 | — | — | — | — | — | — | 1 | 1 |
Covid-19 | D000086382 | — | U07.1 | — | — | — | — | 1 | 1 |
Critical illness | D016638 | — | — | — | — | — | — | 1 | 1 |
Creativity | D003405 | — | — | — | — | — | — | 1 | 1 |
Motivation | D009042 | — | — | — | — | — | — | 1 | 1 |
Reward | D012201 | — | — | — | — | — | — | 1 | 1 |
Drug common name | Modafinil |
INN | modafinil |
Description | 2-[(diphenylmethyl)sulfinyl]acetamide is a sulfoxide that is dimethylsulfoxide in which two hydrogens attached to one of the methyl groups are replaced by phenyl groups, while one hydrogen attached to the other methyl group is replaced by a carbamoyl (aminocarbonyl) group. It is a sulfoxide and a monocarboxylic acid amide. |
Classification | Small molecule |
Drug class | CNS stimulanteugeroic |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | NC(=O)C[S+]([O-])C(c1ccccc1)c1ccccc1 |
PDB | — |
CAS-ID | 112111-43-0 |
RxCUI | 30125 |
ChEMBL ID | CHEMBL1373 |
ChEBI ID | 77585 |
PubChem CID | 4236 |
DrugBank | DB00745 |
UNII ID | R3UK8X3U3D (ChemIDplus, GSRS) |