Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Breast neoplasms | D001943 | EFO_0003869 | C50 | — | 1 | — | — | 1 | 2 |
Large b-cell lymphoma diffuse | D016403 | — | C83.3 | 1 | 1 | — | — | 1 | 2 |
Triple negative breast neoplasms | D064726 | — | — | — | 1 | — | — | — | 1 |
Ischemia | D007511 | EFO_0000556 | — | 1 | 1 | — | — | — | 1 |
Peripheral arterial disease | D058729 | EFO_0004265 | — | 1 | 1 | — | — | — | 1 |
Peripheral vascular diseases | D016491 | EFO_0003875 | I73.9 | 1 | 1 | — | — | — | 1 |
Non-hodgkin lymphoma | D008228 | — | C85.9 | — | 1 | — | — | — | 1 |
Hiv infections | D015658 | EFO_0000764 | B20 | — | 1 | — | — | — | 1 |
Follicular lymphoma | D008224 | — | C82 | 1 | 1 | — | — | — | 1 |
Merkel cell carcinoma | D015266 | EFO_1001471 | C4A | — | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Healthy volunteers/patients | — | — | — | 6 | — | — | — | — | 6 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Sexually transmitted diseases | D012749 | — | A50-A64 | — | — | — | — | 1 | 1 |
Gender identity | D005783 | — | — | — | — | — | — | 1 | 1 |
Transsexualism | D014189 | — | F64.0 | — | — | — | — | 1 | 1 |
Gender dysphoria | D000068116 | — | F64 | — | — | — | — | 1 | 1 |
Obstructive sleep apnea | D020181 | EFO_0003918 | G47.33 | — | — | — | — | 1 | 1 |
Health behavior | D015438 | — | — | — | — | — | — | 1 | 1 |
Parenting | D016487 | — | — | — | — | — | — | 1 | 1 |
Psychological distance | D012929 | — | — | — | — | — | — | 1 | 1 |
Hyponatremia | D007010 | HP_0002902 | E87.1 | — | — | — | — | 1 | 1 |
Skin care | D017592 | — | — | — | — | — | — | 1 | 1 |
Drug common name | Mitoguazone |
INN | mitoguazone |
Description | Mitoguazone is a hydrazone obtained by formal condensation of the two carbonyl groups of methylglyoxal with the primary amino groups of two molecules of aminoguanidine. It has a role as an antineoplastic agent, an apoptosis inducer and an EC 4.1.1.50 (adenosylmethionine decarboxylase) inhibitor. It is a hydrazone and a member of guanidines. It is functionally related to a methylglyoxal and an aminoguanidine. It is a conjugate base of a mitoguazone(2+). |
Classification | Small molecule |
Drug class | — |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | CC(/C=N/NC(=N)N)=N\NC(=N)N |
PDB | — |
CAS-ID | 459-86-9 |
RxCUI | — |
ChEMBL ID | CHEMBL216913 |
ChEBI ID | 43996 |
PubChem CID | 5351154 |
DrugBank | — |
UNII ID | OD5Q0L447W (ChemIDplus, GSRS) |