Therapeutic Area | MeSH |
---|---|
urogenital diseases | D000091642 |
signs and symptoms pathological conditions | D013568 |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
MYRBETRIQ | Astellas Pharma | N-202611 RX | 2012-06-28 | 2 products, RLD, RS |
MYRBETRIQ GRANULES | Astellas Pharma | N-213801 RX | 2021-03-25 | 1 products, RLD, RS |
Indication | Ontology | MeSH | ICD-10 |
---|---|---|---|
overactive urinary bladder | EFO_1000781 | D053201 | N32.81 |
urge urinary incontinence | EFO_0006865 | D053202 | N39.41 |
Expiration | Code | ||
---|---|---|---|
MIRABEGRON, MYRBETRIQ, APGDI | |||
2024-09-25 | PED | ||
2024-03-25 | I-855 | ||
MIRABEGRON, MYRBETRIQ GRANULES, APGDI | |||
2024-09-25 | PED | ||
2024-03-25 | NP |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Overactive urinary bladder | D053201 | EFO_1000781 | N32.81 | 6 | 9 | 17 | 24 | 17 | 71 |
Healthy volunteers/patients | — | — | — | 23 | 1 | — | 2 | — | 26 |
Urge urinary incontinence | D053202 | EFO_0006865 | N39.41 | — | — | 2 | 5 | 1 | 8 |
Urinary incontinence | D014549 | HP_0000020 | R32 | 2 | 1 | 3 | 1 | — | 6 |
Prostatic hyperplasia | D011470 | EFO_0000284 | N40 | 1 | 1 | — | 2 | 1 | 5 |
Obesity | D009765 | EFO_0001073 | E66.9 | — | 2 | — | 2 | — | 4 |
Lower urinary tract symptoms | D059411 | EFO_0008008 | — | — | 2 | — | 1 | 1 | 4 |
Parkinson disease | D010300 | EFO_0002508 | G20 | — | — | — | 3 | — | 3 |
Interstitial cystitis | D018856 | EFO_1000869 | N30.1 | — | — | 2 | 1 | — | 3 |
Nephrolithiasis | D053040 | — | N20.0 | — | — | 1 | 1 | — | 2 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Urinary bladder diseases | D001745 | — | N32.9 | — | 1 | 4 | — | 2 | 7 |
Urologic diseases | D014570 | — | N39.9 | — | 1 | 2 | — | 2 | 5 |
Neurogenic urinary bladder | D001750 | HP_0000011 | N31 | 1 | 2 | 1 | — | — | 3 |
Heart failure | D006333 | HP_0001635 | I50 | — | 3 | 1 | — | — | 3 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Spinal cord injuries | D013119 | EFO_1001919 | — | 1 | 2 | — | — | — | 3 |
Prediabetic state | D011236 | EFO_1001121 | R73.03 | 1 | 1 | — | — | — | 2 |
Erectile dysfunction | D007172 | EFO_0004234 | F52.21 | 1 | 2 | — | — | — | 2 |
Thermogenesis | D022722 | — | — | 2 | 2 | — | — | — | 2 |
Essential thrombocythemia | D013920 | — | D47.3 | — | 1 | — | — | — | 1 |
Polycythemia vera | D011087 | — | D45 | — | 1 | — | — | — | 1 |
Primary myelofibrosis | D055728 | — | D47.4 | — | 1 | — | — | — | 1 |
Prostatic neoplasms | D011471 | — | C61 | — | 1 | — | — | — | 1 |
Blood pressure | D001794 | EFO_0004325 | — | — | 1 | — | — | — | 1 |
Autonomic dysreflexia | D020211 | EFO_1001762 | G90.4 | — | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Pharmacokinetics | D010599 | — | — | 6 | — | — | — | — | 6 |
Biological availability | D001682 | — | — | 2 | — | — | — | — | 2 |
Drug interactions | D004347 | — | — | 2 | — | — | — | — | 2 |
Polycystic ovary syndrome | D011085 | EFO_0000660 | E28.2 | 1 | — | — | — | — | 1 |
Metabolic syndrome | D024821 | EFO_0000195 | E88.810 | 1 | — | — | — | — | 1 |
Esophageal achalasia | D004931 | HP_0002571 | K22.0 | 1 | — | — | — | — | 1 |
Metabolism | D008660 | GO_0008152 | — | 1 | — | — | — | — | 1 |
Intraocular pressure | D007429 | — | — | 1 | — | — | — | — | 1 |
Renal insufficiency | D051437 | HP_0000083 | N19 | 1 | — | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Type 2 diabetes mellitus | D003924 | EFO_0001360 | E11 | — | — | — | — | 2 | 2 |
Sexual behavior | D012725 | — | — | — | — | — | — | 1 | 1 |
Behavior therapy | D001521 | — | — | — | — | — | — | 1 | 1 |
Cardiovascular diseases | D002318 | HP_0001626 | — | — | — | — | — | 1 | 1 |
Nocturnal enuresis | D053206 | — | N39.44 | — | — | — | — | 1 | 1 |
Drug common name | Mirabegron |
INN | mirabegron |
Description | Mirabegron is a monocarboxylic acid amide obtained by formal condensation of the carboxy group of 2-amino-1,3-thiazol-4-ylacetic acid with the anilino group of (1R)-2-{[2-(4-aminophenyl)ethyl]amino}-1-phenylethanol. Used for the treatment of overactive bladder syndrome. It has a role as a beta-adrenergic agonist. It is a member of 1,3-thiazoles, an aromatic amide, a member of ethanolamines and a monocarboxylic acid amide. |
Classification | Small molecule |
Drug class | beta3 adrenoreceptor agonists |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | Nc1nc(CC(=O)Nc2ccc(CCNC[C@H](O)c3ccccc3)cc2)cs1 |
PDB | — |
CAS-ID | 223673-61-8 |
RxCUI | — |
ChEMBL ID | CHEMBL2095212 |
ChEBI ID | 65349 |
PubChem CID | 9865528 |
DrugBank | DB08893 |
UNII ID | MVR3JL3B2V (ChemIDplus, GSRS) |