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AboutPricing
Drug ReportsMinocycline
Minocycline
Amzeeq, Arestin, Emrosi, Minocin, Minocycline, Zilxi (minocycline) is a small molecule pharmaceutical. Minocycline was first approved as Minocin on 1982-01-01. It is used to treat acne vulgaris, anthrax, borrelia infections, chancroid, and cholera amongst others in the USA.
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Clinical
Drug
Target
Variants
Financial
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Events Timeline
5D
1M
3M
6M
YTD
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2Y
5Y
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FDA approval date
EMA approval date
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Commercial
Therapeutic Areas
Therapeutic Area
MeSH
infectionsD007239
respiratory tract diseasesD012140
eye diseasesD005128
urogenital diseasesD000091642
skin and connective tissue diseasesD017437
Trade Name
FDA
EMA
Amzeeq, Arestin, Emrosi, Minocin, Minocycline, Zilxi (discontinued: Dynacin, Minocin, Minocycline, Minolira, Solodyn, Ximino)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Minocycline hydrochloride
Tradename
Company
Number
Date
Products
MINOCINBausch Health CompaniesN-050649 RX1990-05-31
2 products, RLD
AMZEEQJourney MedicalN-212379 RX2019-10-18
1 products, RLD, RS
ZILXIJourney MedicalN-213690 RX2020-05-28
1 products, RLD, RS
EMROSIJourney MedicalN-219015 RX2024-11-01
1 products, RLD, RS
ARESTINOrapharmaN-050781 RX2001-02-16
1 products, RLD, RS
Show 7 discontinued
Labels
FDA
EMA
Brand Name
Status
Last Update
amzeeqNew Drug Application2023-10-01
arestinNew Drug Application2024-05-31
emrosiNew Drug Application2025-04-22
minocinNew Drug Application2025-09-11
minocycline hydrochlorideANDA2025-09-10
minolira extended releaseNew Drug Application2022-11-02
solodynNew Drug Application2011-04-04
zilxiNew Drug Application2024-02-09
Indications
FDA
EMA
Indication
Ontology
MeSH
ICD-10
respiratory tract infections—D012141J06.9
acne vulgarisEFO_0003894D000152L70
cholera—D002771A00
trachoma—D014141A71
escherichia coli infectionsEFO_1001318D004927B96.20
borrelia infectionsEFO_1000842D001899—
anthrax—D000881A22
plagueEFO_0007481D010930A20
mycoplasma infections—D009175—
meningococcal infectionsEFO_0004249D008589A39
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Agency Specific
FDA
EMA
No data
Patent Expiration
Patent
Expires
Flag
FDA Information
Minocycline Hydrochloride, Amzeeq, Journey
103986412037-09-08U-2647
108498472037-09-08U-2647
88651392030-10-01DPU-1631, U-2647
89455162030-10-01DP
89928962030-10-01DPU-1631, U-2647
96757002030-10-01DPU-1631, U-2647
100860802030-10-01U-2647
101372002030-10-01U-2647
102135122030-10-01DPU-1631, U-2647
102654042030-10-01DP
105178822030-10-01U-2647
108211872030-10-01U-2647
Minocycline Hydrochloride, Minolira, Epi Hlth
111035172036-04-07DP
Minocycline Hydrochloride, Solodyn, Bausch
91926152031-11-17DP
75413472027-04-02U-917
75443732027-04-02DP
79194832027-03-07U-124, U-1078
77907052025-06-24U-124, U-1078
82527762025-06-24U-124
82688042025-06-24U-124, U-1078
87226502025-06-24U-1078
Minocycline Hydrochloride, Minocin, Rempex
90848022031-05-12U-282
92781052031-05-12U-282
Minocycline Hydrochloride, Zilxi, Journey
103221862030-10-01U-1631
109461012030-10-01U-1631
ATC Codes
A: Alimentary tract and metabolism drugs
— A01: Stomatological preparations
— A01A: Stomatological preparations
— A01AB: Antiinfectives and antiseptics for local oral treatment
— A01AB23: Minocycline
D: Dermatologicals
— D10: Anti-acne preparations
— D10A: Anti-acne preparations for topical use
— D10AF: Antiinfectives for treatment of acne
— D10AF07: Minocycline
J: Antiinfectives for systemic use
— J01: Antibacterials for systemic use
— J01A: Tetracycline antibiotics
— J01AA: Tetracyclines
— J01AA08: Minocycline
HCPCS
Code
Description
J2265
Injection, minocycline hydrochloride, 1 mg
Clinical
Clinical Trials
305 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
PeriodontitisD010518EFO_0000649K05.3——21—3
Chronic periodontitisD055113EFO_0006343K05.3———1—1
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Peri-implantitisD057873EFO_1001390———3——3
Indications Phases 2
No data
Indications Phases 1
No data
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Periodontal diseasesD010510—K05.6————11
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameMinocycline
INNminocycline
Description
Minocycline is a tetracycline analogue having a dimethylamino group at position 7 and lacking the methyl and hydroxy groups at position 5. It has a role as an antibacterial drug, an Escherichia coli metabolite and a geroprotector. It is a member of tetracyclines, a tetracenomycin and a tertiary alpha-hydroxy ketone. It is a conjugate acid of a minocycline(1-). It is a tautomer of a minocycline zwitterion.
Classification
Small molecule
Drug classantibiotics (tetracycline derivatives)
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
CN(C)c1ccc(O)c2c1C[C@H]1C[C@H]3[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]3(O)C(O)=C1C2=O
Identifiers
PDB—
CAS-ID10118-90-8
RxCUI—
ChEMBL IDCHEMBL1434
ChEBI ID50694
PubChem CID54675783
DrugBankDB01017
UNII IDFYY3R43WGO (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
Revenue by drug
$
€
£
â‚£
Ximino – Fortress Biotech
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Ximino – Journey Medical
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Amzeeq – Fortress Biotech
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Amzeeq – Journey Medical
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Minocin – Melinta Therapeutics /new/
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Minolira – Novan
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Zilxi – Fortress Biotech
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Zilxi – Journey Medical
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Emrosi – Journey Medical
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Tabular view
Estimated US medical usage
Minocycline
Total medical expenditures per year (USD, in millions)
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Number of persons purchased
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Number of purchases
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Refill frequency
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Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 36,507 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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10,192 adverse events reported
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