Indication | Ontology | MeSH | ICD-10 |
---|---|---|---|
gaucher disease | Orphanet_355 | D005776 | E75.22 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Gm2 gangliosidoses | D020143 | Orphanet_309152 | E75.0 | — | 1 | 2 | 1 | — | 4 |
Type c niemann-pick disease | D052556 | Orphanet_646 | E75.242 | — | 1 | 1 | 1 | — | 3 |
Tay-sachs disease | D013661 | Orphanet_845 | E75.02 | — | — | 1 | 1 | — | 2 |
Sandhoff disease | D012497 | Orphanet_796 | E75.01 | — | — | 1 | 1 | — | 2 |
Contraception | D003267 | — | — | — | — | — | 1 | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Glycogen storage disease type ii | D006009 | Orphanet_365 | E74.02 | 2 | 1 | 4 | — | 2 | 8 |
Cystic fibrosis | D003550 | EFO_0000390 | E84 | — | 4 | 1 | — | — | 4 |
Gaucher disease | D005776 | Orphanet_355 | E75.22 | — | 1 | 1 | — | 1 | 3 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Hiv infections | D015658 | EFO_0000764 | B20 | 1 | 2 | — | — | — | 3 |
Hereditary spastic paraplegia | D015419 | EFO_0000529 | G11.4 | — | 1 | — | — | — | 1 |
Neuronal ceroid-lipofuscinoses | D009472 | — | E75.4 | 1 | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Diarrhea | D003967 | HP_0002014 | R19.7 | 1 | — | — | — | — | 1 |
Hypersensitivity | D006967 | HP_0012393 | T78.40 | 1 | — | — | — | — | 1 |
Niemann-pick diseases | D009542 | — | E75.24 | 1 | — | — | — | — | 1 |
Drug common name | Miglustat |
INN | miglustat |
Description | Miglustat is a hydroxypiperidine that is deoxynojirimycin in which the amino hydrogen is replaced by a butyl group. It has a role as an EC 2.4.1.80 (ceramide glucosyltransferase) inhibitor and an anti-HIV agent. It is a member of piperidines and a tertiary amino compound. It is functionally related to a duvoglustat. |
Classification | Small molecule |
Drug class | enzyme inhibitors: glucosyltransferase inhibitors |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | CCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO |
PDB | — |
CAS-ID | 72599-27-0 |
RxCUI | — |
ChEMBL ID | CHEMBL1029 |
ChEBI ID | 50381 |
PubChem CID | 51634 |
DrugBank | DB00419 |
UNII ID | ADN3S497AZ (ChemIDplus, GSRS) |