Therapeutic Area | MeSH |
---|---|
cardiovascular diseases | D002318 |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
ALDOCLOR-150 | Merck KGaA | N-016016 DISCN | 1982-01-01 | 1 products |
ALDOCLOR-250 | Merck KGaA | N-016016 DISCN | 1982-01-01 | 1 products |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
ALDORIL 15 | Merck KGaA | N-013402 DISCN | 1982-01-01 | 1 products |
ALDORIL 25 | Merck KGaA | N-013402 DISCN | 1982-01-01 | 1 products |
ALDORIL D30 | Merck KGaA | N-013402 DISCN | 1982-01-01 | 1 products |
ALDORIL D50 | Merck KGaA | N-013402 DISCN | 1982-01-01 | 1 products |
Tradename | Company | Number | Date | Products |
---|---|---|---|---|
METHYLDOPA | Chartwell Pharmaceuticals | N-018934 RX | 1984-06-29 | 2 products, RS |
Indication | Ontology | MeSH | ICD-10 |
---|---|---|---|
hypertension | EFO_0000537 | D006973 | I10 |
Code | Description |
---|---|
J0210 | Injection, methyldopate hcl, up to 250 mg |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Pre-eclampsia | D011225 | EFO_0000668 | O14 | 1 | 2 | — | 4 | 2 | 8 |
Hypertension | D006973 | EFO_0000537 | I10 | 1 | 1 | — | 1 | 3 | 5 |
Pregnancy-induced hypertension | D046110 | — | O13 | — | — | — | 2 | 1 | 3 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Type 1 diabetes mellitus | D003922 | EFO_0001359 | E10 | 1 | 1 | — | — | 1 | 3 |
Brain injuries | D001930 | — | S06.9 | 1 | 1 | — | — | — | 1 |
Proteinuria | D011507 | HP_0000093 | R80 | 1 | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Orthostatic intolerance | D054971 | — | — | 2 | — | — | — | — | 2 |
Autonomic nervous system diseases | D001342 | EFO_0009532 | G90 | 1 | — | — | — | — | 1 |
Orthostatic hypotension | D007024 | — | I95.1 | 1 | — | — | — | — | 1 |
Healthy volunteers/patients | — | — | — | 1 | — | — | — | — | 1 |
Postural orthostatic tachycardia syndrome | D054972 | — | G90.A | 1 | — | — | — | — | 1 |
Chronic fatigue syndrome | D015673 | EFO_0004540 | G93.31 | 1 | — | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Covid-19 | D000086382 | — | U07.1 | — | — | — | — | 1 | 1 |
Hellp syndrome | D017359 | EFO_0007297 | O14.2 | — | — | — | — | 1 | 1 |
Drug common name | Methyldopa |
INN | methyldopa |
Description | Alpha-methyl-L-dopa is a derivative of L-tyrosine having a methyl group at the alpha-position and an additional hydroxy group at the 3-position on the phenyl ring. It has a role as a hapten, an antihypertensive agent, an alpha-adrenergic agonist, a peripheral nervous system drug and a sympatholytic agent. It is a L-tyrosine derivative and a non-proteinogenic L-alpha-amino acid. |
Classification | Small molecule |
Drug class | dopamine receptor agonists |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | C[C@](N)(Cc1ccc(O)c(O)c1)C(=O)O |
PDB | — |
CAS-ID | 555-30-6 |
RxCUI | — |
ChEMBL ID | CHEMBL459 |
ChEBI ID | 61058 |
PubChem CID | 38853 |
DrugBank | DB00968 |
UNII ID | M4R0H12F6M (ChemIDplus, GSRS) |