Methylcobalamin
Methylcobalamin is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Drug Products
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FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| healthy mamabe well rounded | unapproved drug other | 2013-07-09 |
| matervia | unapproved drug other | 2025-06-11 |
| methylcobalamin | unapproved drug other | 2015-11-20 |
Indications
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Clinical
Clinical Trials
579 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Non-small-cell lung carcinoma | D002289 | — | — | — | 2 | 2 | — | — | 4 |
| Lung neoplasms | D008175 | — | C34.90 | — | 1 | 2 | — | — | 3 |
| Cardiovascular diseases | D002318 | EFO_0000319 | I98 | — | — | 1 | — | — | 1 |
Indications Phases 2
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Colorectal neoplasms | D015179 | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Methylcobalamin |
| INN | mecobalamin |
| Description | Methylcobalamin (mecobalamin, MeCbl, or MeB12) is a cobalamin, a form of vitamin B12. It differs from cyanocobalamin in that the cyano group at the cobalt is replaced with a methyl group. Methylcobalamin features an octahedral cobalt(III) centre and can be obtained as bright red crystals. From the perspective of coordination chemistry, methylcobalamin is notable as a rare example of a compound that contains metal–alkyl bonds. Nickel–methyl intermediates have been proposed for the final step of methanogenesis.
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| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | — |
Identifiers
| PDB | — |
| CAS-ID | 13422-55-4 |
| RxCUI | — |
| ChEMBL ID | CHEMBL4297672 |
| ChEBI ID | — |
| PubChem CID | 6436232 |
| DrugBank | DB03614 |
| UNII ID | BR1SN1JS2W (ChemIDplus, GSRS) |
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Methylcobalamin
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Trends
PubMed Central
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Additional graphs summarizing 4,215 documents
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Safety
Black-box Warning
Black-box warning for: Healthy mamabe well rounded
Adverse Events
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565 adverse events reported
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