PharmaKB logo
Company Reports
Company Reports
Drug Reports
Drug Reports
Disease Reports
Disease Reports
Sets
Sets
Favorites
Favorites
Log in
Log in
AboutPricing
Drug ReportsMethylcobalamin
Methylcobalamin
Methylcobalamin is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
Download report
Favorite
Events Timeline
Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
Plot placeholder
Mock data
Subscribe for the real data
Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
No data
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
No data
Labels
FDA
EMA
Brand Name
Status
Last Update
embrivaunapproved drug other2025-08-12
gestyraunapproved drug other2025-12-30
healthy mamabe well roundedunapproved drug other2013-07-09
materviaunapproved drug other2025-06-11
methylcobalaminunapproved drug other2015-11-20
Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
B: Blood and blood forming organ drugs
— B03: Antianemic preparations
— B03B: Vitamin b12 and folic acid
— B03BA: Vitamin b12 (cyanocobalamin and analogues)
— B03BA05: Mecobalamin
HCPCS
No data
Clinical
Clinical Trials
605 clinical trials
View more details
Plot placeholder
Mock data
Subscribe for the real data
Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Vitamin b 12 deficiencyD014806EFO_0000734E53.824254354
AnemiaD000740EFO_0004272D64.9—4543041
Diabetic neuropathiesD003929EFO_1000783—13211218
Diabetes mellitusD003920EFO_0000400E08-E13—333816
Peripheral nervous system diseasesD010523—G641312814
HyperhomocysteinemiaD020138———1111114
Iron-deficiency anemiaD018798—D50———31013
Iron deficienciesD000090463—E61.1———21113
Cognitive dysfunctionD060825—G31.8412—1812
ObesityD009765EFO_0001073E66.911—2711
Show 54 more
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Non-small-cell lung carcinomaD002289——1157—223
MalnutritionD044342EFO_0008572E40-E46—22—1417
AvitaminosisD001361EFO_0005878E56.9—23—1013
Cardiovascular diseasesD002318EFO_0000319I98—43—611
Type 2 diabetes mellitusD003924EFO_0001360E11—42—711
Parkinson diseaseD010300EFO_0002508G20—11—910
PregnancyD011247EFO_0002950Z33.11—1—79
Covid-19D000086382—U07.1123—38
Lung neoplasmsD008175—C34.90172——8
StrokeD020521EFO_0000712I63.9—14—37
Show 78 more
Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients———12——912
RecurrenceD012008——54———7
Brain injuriesD001930—S06.921——35
MicronutrientsD018977———1——34
DiarrheaD003967—R19.7—1——34
FibromyalgiaD005356EFO_0005687M79.121——24
Thyroid diseasesD013959—E00-E07—1——23
Nasopharyngeal carcinomaD000077274———3———3
StomatitisD013280EFO_1001904K12.1—3———3
Nasopharyngeal neoplasmsD009303———3———3
Show 66 more
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
InflammationD007249MP_0001845—1———1011
Weight lossD015431——1———45
Child developmentD002657——1———23
HypertensionD006973EFO_0000537I101———23
Heart failureD006333EFO_0003144I501———23
Sezary syndromeD012751—C84.12————2
Mycosis fungoidesD009182—C84.02————2
T-cell lymphoma cutaneousD016410—C84.A2————2
Multiple sclerosisD009103EFO_0003885G351———12
GliomaD005910EFO_0000520—1————1
Show 10 more
Indications Without Phase
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Folic acid deficiencyD005494EFO_0001070E53.8————99
Deglutition disordersD003680—R13.1————88
Gyrate atrophyD015799——————66
Metabolic syndromeD024821EFO_0000195E88.810————66
Gastroesophageal refluxD005764EFO_0003948K21————66
Male infertilityD007248EFO_0004248N46————55
FatigueD005221—R53.83————55
Cerebral palsyD002547—G80————44
Vitamin a deficiencyD014802EFO_1001237E50————44
InfertilityD007246EFO_0000545—————44
Show 198 more
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
Drug common nameMethylcobalamin
INNmecobalamin
Description
Methylcobalamin (mecobalamin, MeCbl, or MeB12) is a cobalamin, a form of vitamin B12. It differs from cyanocobalamin in that the cyano group at the cobalt is replaced with a methyl group. Methylcobalamin features an octahedral cobalt(III) centre and can be obtained as bright red crystals. From the perspective of coordination chemistry, methylcobalamin is notable as a rare example of a compound that contains metal–alkyl bonds. Nickel–methyl intermediates have been proposed for the final step of methanogenesis.
Classification
Small molecule
Drug class—
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)—
Identifiers
PDB—
CAS-ID13422-55-4
RxCUI—
ChEMBL IDCHEMBL4297672
ChEBI ID—
PubChem CID6436232
DrugBankDB03614
UNII IDBR1SN1JS2W (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
Revenue by drug
$
€
£
₣
No data
Estimated US medical usage
Methylcobalamin
Total medical expenditures per year (USD, in millions)
Plot placeholder
Mock data
Subscribe for the real data
Number of persons purchased
Plot placeholder
Mock data
Subscribe for the real data
Number of purchases
Plot placeholder
Mock data
Subscribe for the real data
Refill frequency
Plot placeholder
Mock data
Subscribe for the real data
Price per prescription (USD)
Plot placeholder
Mock data
Subscribe for the real data
Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Plot placeholder
Mock data
Subscribe for the real data
Additional graphs summarizing 4,878 documents
View more details
Safety
Black-box Warning
Black-box warning for: Healthy mamabe well rounded
Adverse Events
Top Adverse Reactions
Plot placeholder
Mock data
Subscribe for the real data
701 adverse events reported
View more details
© 2020-2025 Collaborative Drug Discovery Inc. (CDD) | Terms of Use