Methoxyflurane
Methoxyflurane is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Drug Products
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New Drug Application (NDA)
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Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| ammonia | unapproved drug other | 2021-09-02 |
| ammonia inhalant | unapproved drug other | 2020-04-27 |
| ammonia inhalants | unapproved drug other | 2025-08-11 |
| bardown smelling salts | unapproved drug other | 2025-04-16 |
| first aid only ammonia inhalants | unapproved drug other | 2018-02-19 |
| physician ez use joint tunnel and trigger kit | unapproved drug other | 2024-10-05 |
| shock-x ammonia inhalant | C200263 | 2025-06-08 |
| yep wake the faith up ammonia inhalant | unapproved drug other | 2025-02-15 |
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Agency Specific
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Clinical
Clinical Trials
34 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Acute pain | D059787 | — | R52 | — | — | 5 | 7 | 1 | 13 |
| Wounds and injuries | D014947 | — | T14.8 | — | — | 2 | 2 | 1 | 5 |
| Emergencies | D004630 | — | — | — | — | 2 | 2 | — | 4 |
| Pain | D010146 | EFO_0003843 | R52 | — | — | — | 2 | 2 | 4 |
| Analgesia | D000698 | — | — | — | — | — | 1 | 1 | 2 |
| Hypovolemia | D020896 | — | E86 | — | — | — | 2 | — | 2 |
| Shoulder dislocation | D012783 | — | S43.0 | — | — | — | 1 | 1 | 2 |
| Angina pectoris | D000787 | EFO_0003913 | I20 | — | — | — | 1 | — | 1 |
| Unstable angina | D000789 | EFO_1000985 | I20.0 | — | — | — | 1 | — | 1 |
| Low cardiac output | D002303 | — | — | — | — | — | 1 | — | 1 |
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Bone fractures | D050723 | EFO_0003931 | T14.8 | — | — | 1 | — | — | 1 |
| Myocardial infarction | D009203 | EFO_0000612 | I21 | — | — | 1 | — | — | 1 |
| Acute coronary syndrome | D054058 | EFO_0005672 | — | — | — | 1 | — | — | 1 |
| St elevation myocardial infarction | D000072657 | — | — | — | — | 1 | — | — | 1 |
| Infarction | D007238 | EFO_0009463 | — | — | — | 1 | — | — | 1 |
| Neoplasms | D009369 | — | C80 | — | — | 1 | — | — | 1 |
| Toothache | D014098 | — | K08.89 | — | — | 1 | — | — | 1 |
| Sensation disorders | D012678 | — | H02.59 | — | — | 1 | — | — | 1 |
| Prostatic hyperplasia | D011470 | EFO_0000284 | N40 | — | — | 1 | — | — | 1 |
| Hyperplasia | D006965 | EFO_0000536 | — | — | — | 1 | — | — | 1 |
Show 1 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Rhinosinusitis | D000096825 | — | — | 1 | 1 | — | — | — | 1 |
| Local anesthesia | D000772 | — | — | — | 1 | — | — | — | 1 |
| Spermatocele | D013088 | EFO_1001189 | N43.4 | — | 1 | — | — | — | 1 |
| Hematocele | D006398 | — | — | — | 1 | — | — | — | 1 |
Indications Phases 1
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Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Traumatic brain injuries | D000070642 | — | S06 | — | — | — | — | 1 | 1 |
| Joint dislocations | D004204 | — | — | — | — | — | — | 1 | 1 |
| Pain management | D059408 | — | — | — | — | — | — | 1 | 1 |
| Respiratory aspiration | D053120 | EFO_1001839 | — | — | — | — | — | 1 | 1 |
| Intrauterine devices | D007434 | — | — | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Methoxyflurane |
| INN | methoxyflurane |
| Description | Methoxyflurane is an ether in which the two groups attached to the central oxygen atom are methyl and 2,2-dichloro-1,1-difluoroethyl. It has a role as an inhalation anaesthetic, a non-narcotic analgesic, a hepatotoxic agent and a nephrotoxic agent. It is an organofluorine compound, an organochlorine compound and an ether. |
| Classification | Small molecule |
| Drug class | general inhalation anesthetics (halogenated alkane derivatives) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | COC(F)(F)C(Cl)Cl |
Identifiers
| PDB | — |
| CAS-ID | 76-38-0 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1341 |
| ChEBI ID | 6843 |
| PubChem CID | 4116 |
| DrugBank | DB01028 |
| UNII ID | 30905R8O7B (ChemIDplus, GSRS) |
Target
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Trends
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Safety
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Adverse Events
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98 adverse events reported
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