Methoxsalen
Methoxsalen, Oxsoralen-ultra, Uvadex (methoxsalen) is a small molecule pharmaceutical. Methoxsalen was first approved as 8-mop on 1982-01-01. It is used to treat mycosis fungoides, psoriasis, and vitiligo in the USA.
Download report
Favorite
Events Timeline
Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
Mock data
Subscribe for the real data
Subscribe for the real data
Commercial
Therapeutic Areas
Trade Name
FDA
EMA
Methoxsalen, Oxsoralen-ultra, Uvadex (discontinued: Methoxsalen, Oxsoralen)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Methoxsalen
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| OXSORALEN-ULTRA | Bausch Health Companies | N-019600 RX | 1986-10-30 | 1 products, RLD, RS |
| UVADEX | Mallinckrodt | N-020969 RX | 1999-02-25 | 1 products, RLD, RS |
Show 2 discontinued
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| methoxsalen | ANDA | 2025-03-11 |
| uvadex | New Drug Application | 2024-12-16 |
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| psoriasis | EFO_0000676 | D011565 | L40 |
| vitiligo | EFO_0004208 | D014820 | L80 |
| mycosis fungoides | — | D009182 | C84.0 |
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
HCPCS
No data
Clinical
Clinical Trials
68 clinical trials
View more details
Mock data
Subscribe for the real data
Subscribe for the real data
Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| T-cell lymphoma cutaneous | D016410 | — | C84.A | 1 | 4 | — | 2 | 1 | 7 |
| Mycosis fungoides | D009182 | — | C84.0 | — | 2 | 2 | 2 | — | 6 |
| Lymphoma | D008223 | — | C85.9 | 1 | 1 | 1 | 1 | 1 | 5 |
| Mycoses | D009181 | — | B35-B49 | — | 1 | 2 | 2 | — | 5 |
| T-cell lymphoma | D016399 | — | — | — | 2 | — | 1 | — | 3 |
| T-cell lymphoma peripheral | D016411 | — | — | — | — | — | 1 | — | 1 |
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Graft vs host disease | D006086 | — | D89.81 | 2 | 9 | 3 | — | 3 | 16 |
| Neoplasms | D009369 | — | C80 | 1 | 3 | 2 | — | — | 4 |
| Bronchiolitis obliterans syndrome | D000092122 | — | D89.811 | 1 | 2 | 1 | — | — | 4 |
| Syndrome | D013577 | — | — | 1 | — | 1 | — | 1 | 3 |
| Atopic dermatitis | D003876 | EFO_0000274 | L20 | — | — | 1 | — | 2 | 3 |
| Eczema | D004485 | — | L30.9 | — | — | 1 | — | 2 | 3 |
| Dermatitis | D003872 | — | L30.9 | — | — | 1 | — | 2 | 3 |
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | — | 1 | 2 | — | — | 2 |
| Neoplasm metastasis | D009362 | EFO_0009708 | — | — | 1 | 1 | — | — | 1 |
| Psoriasis | D011565 | EFO_0000676 | L40 | — | — | 1 | — | — | 1 |
Show 3 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Leukemia | D007938 | — | C95 | 2 | 1 | — | — | 1 | 4 |
| Addictive behavior | D016739 | EFO_0004347 | — | — | 1 | — | — | 1 | 2 |
| Myelodysplastic syndromes | D009190 | — | D46 | 1 | 1 | — | — | — | 2 |
| Sarcoma | D012509 | — | — | 1 | 1 | — | — | — | 2 |
| Prostatic neoplasms | D011471 | — | C61 | 1 | 1 | — | — | 1 | 2 |
| Melanoma | D008545 | — | — | 1 | 1 | — | — | — | 2 |
| Hematologic neoplasms | D019337 | — | — | 1 | 2 | — | — | — | 2 |
| Sezary syndrome | D012751 | — | C84.1 | — | 1 | — | — | 1 | 2 |
| Non-small-cell lung carcinoma | D002289 | — | — | 1 | 1 | — | — | — | 2 |
| Crohn disease | D003424 | EFO_0000384 | K50 | 1 | 1 | — | — | — | 2 |
Show 25 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hiv infections | D015658 | EFO_0000764 | B20 | 1 | — | — | — | 1 | 2 |
| Lung neoplasms | D008175 | — | C34.90 | 1 | — | — | — | — | 1 |
| Multiple myeloma | D009101 | — | C90.0 | 1 | — | — | — | — | 1 |
| Plasma cell neoplasms | D054219 | — | — | 1 | — | — | — | — | 1 |
| Preleukemia | D011289 | — | — | 1 | — | — | — | — | 1 |
| Plasmacytoma | D010954 | — | C90.3 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Graft rejection | D006084 | — | — | — | — | — | — | 4 | 4 |
| Covid-19 | D000086382 | — | U07.1 | — | — | — | — | 2 | 2 |
| Opioid-related disorders | D009293 | EFO_0005611 | F11 | — | — | — | — | 1 | 1 |
| Alopecia areata | D000506 | EFO_0004192 | L63 | — | — | — | — | 1 | 1 |
| Alopecia | D000505 | — | L64 | — | — | — | — | 1 | 1 |
| Chronic progressive multiple sclerosis | D020528 | EFO_0003840 | — | — | — | — | — | 1 | 1 |
| Kidney transplantation | D016030 | — | — | — | — | — | — | 1 | 1 |
| Aids-related complex | D000386 | EFO_0007137 | B20 | — | — | — | — | 1 | 1 |
| Infections | D007239 | EFO_0000544 | — | — | — | — | — | 1 | 1 |
| Communicable diseases | D003141 | — | — | — | — | — | — | 1 | 1 |
Show 11 more
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
| Drug common name | Methoxsalen |
| INN | — |
| Description | Methoxsalen is a member of the class of psoralens that is 7H-furo[3,2-g]chromen-7-one in which the 9 position is substituted by a methoxy group. It is a constituent of the fruits of Ammi majus. Like other psoralens, trioxsalen causes photosensitization of the skin. It is administered topically or orally in conjunction with UV-A for phototherapy treatment of vitiligo and severe psoriasis. It has a role as a dermatologic drug, an antineoplastic agent, a photosensitizing agent, a cross-linking reagent and a plant metabolite. It is a member of psoralens and an aromatic ether. It is functionally related to a psoralen. |
| Classification | Small molecule |
| Drug class | anti-inflammatory agents (salicylic acid derivatives) |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | COc1c2occc2cc2ccc(=O)oc12 |
Target
No data
Variants
No data
Financial
Revenue by drug
$
€
£
₣
No data
Estimated US medical usage
Methoxsalen
Total medical expenditures per year (USD, in millions)
Mock data
Subscribe for the real data
Subscribe for the real data
Number of persons purchased
Mock data
Subscribe for the real data
Subscribe for the real data
Number of purchases
Mock data
Subscribe for the real data
Subscribe for the real data
Refill frequency
Mock data
Subscribe for the real data
Subscribe for the real data
Price per prescription (USD)
Mock data
Subscribe for the real data
Subscribe for the real data
Tabular view
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Subscribe for the real data
Additional graphs summarizing 1,914 documents
View more details
Safety
Black-box Warning
Black-box warning for: Methoxsalen, Uvadex
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
Subscribe for the real data
716 adverse events reported
View more details
© 2020-2025 Collaborative Drug Discovery Inc. (CDD) | Terms of Use