Methenamine
Hiprex, Methenamine Hippurate, Urex (methenamine) is a small molecule pharmaceutical. Methenamine was first approved as Urex on 1982-01-01. It is used to treat bacteriuria, cystitis, escherichia coli infections, and staphylococcal infections in the USA.
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Commercial
Therapeutic Areas
Therapeutic Area | MeSH |
|---|---|
| infections | D007239 |
| urogenital diseases | D000091642 |
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Drug Products
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Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| all-in-one uti emergency kit | unapproved drug other | 2024-12-17 |
| azo urinary tract defense | unapproved drug other | 2020-12-12 |
| cvs antibacterial plus urinary pain relief | unapproved drug other | 2024-12-18 |
| cvs dual action pain relief | unapproved drug other | 2024-12-18 |
| cystex | C200263 | 2024-12-20 |
| good neighbor antibacterial plus urinary pain relief | unapproved drug other | 2024-12-18 |
| hiprex | New Drug Application | 2022-02-02 |
| hyophen | unapproved drug other | 2017-01-05 |
| mb caps | unapproved drug other | 2025-02-25 |
| meijer antibacterial plus urinary pain relief | unapproved drug other | 2024-12-18 |
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Indications
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Clinical
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29 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Overactive urinary bladder | D053201 | EFO_1000781 | N32.81 | 1 | — | — | — | — | 1 |
Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Methenamine |
| INN | methenamine |
| Description | Hexamethylenetetramine is a polycyclic cage that is adamantane in which the carbon atoms at positions 1, 3, 5 and 7 are replaced by nitrogen atoms. It has a role as an antibacterial drug. It is a polycyclic cage, a polyazaalkane and a tetramine. |
| Classification | Small molecule |
| Drug class | Antiseptic; Antibacterial |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | C1N2CN3CN1CN(C2)C3 |
Identifiers
| PDB | — |
| CAS-ID | 100-97-0 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1201270 |
| ChEBI ID | 6824 |
| PubChem CID | 4101 |
| DrugBank | DB06799 |
| UNII ID | J50OIX95QV (ChemIDplus, GSRS) |
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Methenamine
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Safety
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453 adverse events reported
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