Tradename | Company | Number | Date | Products |
---|---|---|---|---|
MEROPENEM AND SODIUM CHLORIDE IN DUPLEX CONTAINER | B. Braun Medical | N-202106 RX | 2015-04-30 | 2 products |
MEROPENEM | HQ Specialty Pharma | N-215212 RX | 2023-07-26 | 1 products, RLD, RS |
Brand Name | Status | Last Update |
---|---|---|
meropenem | ANDA | 2025-07-01 |
meropenem and sodium chloride | New Drug Application | 2024-12-03 |
meropenem meropenem | ANDA | 2019-05-24 |
vabomere | New Drug Application | 2025-03-25 |
Expiration | Code | ||
---|---|---|---|
MEROPENEM / VABORBACTAM, VABOMERE, REMPEX | |||
2027-08-29 | GAIN | ||
2022-08-29 | NCE |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Infections | D007239 | EFO_0000544 | — | 6 | 15 | 26 | 15 | 19 | 77 |
Communicable diseases | D003141 | — | — | 3 | 12 | 20 | 9 | 11 | 53 |
Sepsis | D018805 | EFO_0001420 | A41.9 | 5 | 9 | 12 | 10 | 16 | 43 |
Pneumonia | D011014 | EFO_0003106 | J18 | 1 | 5 | 16 | 9 | 7 | 37 |
Urinary tract infections | D014552 | EFO_0003103 | N39.0 | 1 | 4 | 12 | 2 | 2 | 21 |
Bacterial infections | D001424 | — | A49 | 6 | 1 | 1 | 8 | 6 | 21 |
Intraabdominal infections | D059413 | — | — | 1 | 7 | 11 | 1 | — | 18 |
Bacteremia | D016470 | EFO_0003033 | R78.81 | — | — | 4 | 5 | 7 | 16 |
Critical illness | D016638 | — | — | — | 1 | — | 4 | 11 | 16 |
Ventilator-associated pneumonia | D053717 | EFO_1001865 | J95.851 | — | 2 | 11 | 2 | 1 | 15 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Appendicitis | D001064 | EFO_0007149 | K37 | — | 1 | 3 | — | 1 | 4 |
Sinusitis | D012852 | EFO_0007486 | J32 | — | — | 1 | — | 1 | 2 |
Liver cirrhosis | D008103 | EFO_0001422 | K74.0 | — | 1 | 1 | — | 1 | 2 |
Neonatal sepsis | D000071074 | — | — | — | — | 1 | — | 1 | 2 |
Iatrogenic disease | D007049 | — | — | — | 1 | 1 | — | — | 2 |
Abscess | D000038 | EFO_0003030 | — | — | — | 2 | — | — | 2 |
Ascites | D001201 | — | R18 | — | 1 | 1 | — | — | 1 |
Lung diseases | D008171 | EFO_0003818 | J98.4 | — | — | 1 | — | — | 1 |
Infectious skin diseases | D012874 | — | — | — | — | 1 | — | — | 1 |
Cellulitis | D002481 | EFO_0003035 | L03.90 | — | — | 1 | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Cross infection | D003428 | — | — | — | 1 | — | — | 2 | 3 |
Pulmonary tuberculosis | D014397 | EFO_1000049 | A15 | — | 3 | — | — | — | 3 |
Osteomyelitis | D010019 | EFO_0003102 | M86 | 1 | 1 | — | — | — | 2 |
Meningitis | D008581 | EFO_0000584 | G03 | 1 | 1 | — | — | 1 | 2 |
Melioidosis | D008554 | — | A24.9 | — | 1 | — | — | 1 | 2 |
Neoplasms | D009369 | — | C80 | — | 2 | — | — | — | 2 |
Respiratory insufficiency | D012131 | — | J96.9 | 1 | 1 | — | — | — | 1 |
Necrotizing enterocolitis | D020345 | EFO_0003928 | K55.3 | 1 | 1 | — | — | — | 1 |
Enterocolitis | D004760 | EFO_1001481 | — | 1 | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Renal insufficiency | D051437 | — | N19 | 2 | — | — | — | 3 | 5 |
Diabetes mellitus | D003920 | EFO_0000400 | E08-E13 | 1 | — | — | — | — | 1 |
Inflammation | D007249 | MP_0001845 | — | 1 | — | — | — | — | 1 |
Osteoporosis | D010024 | EFO_0003882 | M81.0 | 1 | — | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Pharmacokinetics | D010599 | — | — | — | — | — | — | 7 | 7 |
Acute kidney injury | D058186 | — | N17 | — | — | — | — | 4 | 4 |
Drug monitoring | D016903 | — | — | — | — | — | — | 3 | 3 |
Hemorrhage | D006470 | MP_0001914 | R58 | — | — | — | — | 2 | 2 |
Enterococcus | D016983 | — | — | — | — | — | — | 2 | 2 |
Renal replacement therapy | D017582 | — | — | — | — | — | — | 2 | 2 |
End stage liver disease | D058625 | EFO_1001311 | K72.1 | — | — | — | — | 2 | 2 |
Liver failure | D017093 | — | K72.9 | — | — | — | — | 2 | 2 |
Acute-on-chronic liver failure | D065290 | — | — | — | — | — | — | 2 | 2 |
Heart failure | D006333 | EFO_0003144 | I50 | — | — | — | — | 1 | 1 |
Drug common name | Meropenem |
INN | meropenem |
Description | Meropenem is a carbapenemcarboxylic acid in which the azetidine and pyrroline rings carry 1-hydroxymethyl and in which the azetidine and pyrroline rings carry 1-hydroxymethyl and 5-(dimethylcarbamoyl)pyrrolidin-3-ylthio substituents respectively. It has a role as an antibacterial drug, an antibacterial agent and a drug allergen. It is a carbapenemcarboxylic acid, a pyrrolidinecarboxamide, an alpha,beta-unsaturated monocarboxylic acid and an organic sulfide. |
Classification | Small molecule |
Drug class | antibacterial antibiotics, carbapenem derivatives |
Image (chem structure or protein) | ![]() |
Structure (InChI/SMILES or Protein Sequence) | C[C@@H](O)[C@H]1C(=O)N2C(C(=O)O)=C(S[C@@H]3CN[C@H](C(=O)N(C)C)C3)[C@H](C)[C@H]12 |
PDB | — |
CAS-ID | 96036-03-2 |
RxCUI | — |
ChEMBL ID | CHEMBL127 |
ChEBI ID | 43968 |
PubChem CID | 441130 |
DrugBank | DB00760 |
UNII ID | YOP6PX0BAO (ChemIDplus, GSRS) |