Tradename | Company | Number | Date | Products |
---|---|---|---|---|
PURIXAN | Nova Laboratories | N-205919 RX | 2014-04-28 | 1 products, RLD, RS |
PURINETHOL | Stason Pharmaceuticals | N-009053 RX | 1982-01-01 | 1 products, RLD |
Code | Description |
---|---|
S0108 | Mercaptopurine, oral, 50 mg |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Precursor cell lymphoblastic leukemia-lymphoma | D054198 | — | C91.0 | 18 | 52 | 39 | 17 | 11 | 122 |
Crohn disease | D003424 | EFO_0000384 | K50 | 3 | 4 | 2 | 5 | 5 | 16 |
Inflammatory bowel diseases | D015212 | EFO_0003767 | — | — | — | — | 4 | 11 | 15 |
Ulcerative colitis | D003093 | EFO_0000729 | K51 | — | 1 | 1 | 4 | 6 | 12 |
Promyelocytic leukemia acute | D015473 | — | C92.4 | — | — | 4 | 3 | — | 7 |
Pancreatitis | D010195 | HP_0001733 | K85 | — | — | — | 1 | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Leukemia | D007938 | — | C95 | 2 | 25 | 30 | — | 4 | 56 |
Lymphoma | D008223 | — | C85.9 | — | 2 | 10 | — | — | 12 |
Myeloid leukemia acute | D015470 | — | C92.0 | 1 | 1 | 5 | — | 2 | 9 |
Philadelphia chromosome | D010677 | — | — | 2 | 4 | 2 | — | — | 6 |
Down syndrome | D004314 | EFO_0001064 | Q90 | — | 2 | 3 | — | — | 5 |
T-cell leukemia | D015458 | — | — | — | 3 | 2 | — | — | 3 |
Langerhans-cell histiocytosis | D006646 | — | C96.6 | — | 1 | 3 | — | — | 3 |
B-cell leukemia | D015448 | — | — | — | 2 | 1 | — | — | 2 |
Mucositis | D052016 | EFO_1001898 | — | — | — | 1 | — | — | 1 |
Cardiotoxicity | D066126 | EFO_1001482 | — | — | — | 1 | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Biphenotypic leukemia acute | D015456 | — | C95.0 | 2 | 2 | — | — | — | 3 |
Non-hodgkin lymphoma | D008228 | — | C85.9 | 1 | 2 | — | — | — | 2 |
Systemic lupus erythematosus | D008180 | HP_0002725 | M32 | — | 1 | — | — | 1 | 2 |
Glioblastoma | D005909 | EFO_0000515 | — | 1 | 2 | — | — | — | 2 |
Burkitt lymphoma | D002051 | — | C83.7 | 1 | 1 | — | — | — | 1 |
Neutropenia | D009503 | — | D70 | — | 1 | — | — | — | 1 |
Thrombocytopenia | D013921 | HP_0001873 | D69.6 | — | 1 | — | — | — | 1 |
Hermanski-pudlak syndrome | D022861 | — | E70.331 | — | 1 | — | — | — | 1 |
Colitis | D003092 | EFO_0003872 | K52.9 | — | 1 | — | — | — | 1 |
Lymphocytosis | D008218 | — | — | — | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Healthy volunteers/patients | — | — | — | 1 | — | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Drug-related side effects and adverse reactions | D064420 | — | T88.7 | — | — | — | — | 3 | 3 |
Thrombocytopenic purpura idiopathic | D016553 | EFO_0007160 | D69.3 | — | — | — | — | 1 | 1 |
Psoriasis | D011565 | EFO_0000676 | L40 | — | — | — | — | 1 | 1 |
Squamous intraepithelial lesions | D000081483 | — | — | — | — | — | — | 1 | 1 |
Ataxia telangiectasia | D001260 | Orphanet_100 | G11.3 | — | — | — | — | 1 | 1 |
Herpes zoster | D006562 | EFO_0006510 | B02 | — | — | — | — | 1 | 1 |
Clostridioides difficile | D016360 | NCBITaxon_1496 | — | — | — | — | — | 1 | 1 |
Cytomegalovirus infections | D003586 | EFO_0001062 | B25 | — | — | — | — | 1 | 1 |
Drug common name | Mercaptopurine |
INN | mercaptopurine |
Description | Purine-6-thiol is a thiol that is the tautomer of mercaptopurine. It has a role as an antineoplastic agent and an antimetabolite. It is a tautomer of a mercaptopurine. It derives from a hydride of a 7H-purine. |
Classification | Small molecule |
Drug class | aptamers, classical and mirror |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | O.S=c1[nH]cnc2nc[nH]c12 |
PDB | — |
CAS-ID | 6112-76-1 |
RxCUI | — |
ChEMBL ID | CHEMBL1200751 |
ChEBI ID | 31822 |
PubChem CID | 667490 |
DrugBank | DB01033 |
UNII ID | PKK6MUZ20G (ChemIDplus, GSRS) |