Mepivacaine
Carbocaine, Polocaine, Polocaine-mpf, Scandonest (mepivacaine) is a small molecule pharmaceutical. Mepivacaine was first approved as Carbocaine w/ neo-cobefrin on 1982-01-01. It is used to treat pain in the USA.
Download report
Favorite
Events Timeline
Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
Mock data
Subscribe for the real data
Subscribe for the real data
Commercial
Therapeutic Areas
Trade Name
FDA
EMA
Carbocaine (generic drugs available since 1984-10-10, discontinued: Arestocaine, Isocaine, Polocaine)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Levonordefrin
+
Mepivacaine hydrochloride
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| CARBOCAINE W/ NEO-COBEFRIN | Eastman Kodak | N-012125 DISCN | 1982-01-01 | 1 products |
Hide discontinued
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| leep redikit | unapproved drug other | 2023-10-26 |
| polocaine (mepivacaine hcl) | ANDA | 2024-01-30 |
| polocaine(r) -mpf (mepivacaine hci) | ANDA | 2024-01-29 |
| scandonest 2% l | ANDA | 2022-02-10 |
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| pain | EFO_0003843 | D010146 | R52 |
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
HCPCS
Code | Description |
|---|---|
| J0670 | Injection, mepivacaine hydrochloride, per 10 ml |
Clinical
Clinical Trials
140 clinical trials
View more details
Mock data
Subscribe for the real data
Subscribe for the real data
Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Anesthesia | D000758 | — | — | — | — | — | 4 | 8 | 12 |
| Pain | D010146 | EFO_0003843 | R52 | — | — | 1 | 5 | 4 | 10 |
| Postoperative pain | D010149 | — | G89.18 | — | — | 1 | 3 | 5 | 9 |
| Pulpitis | D011671 | EFO_1001139 | K04.0 | — | 1 | 1 | 1 | 3 | 5 |
| Hip osteoarthritis | D015207 | EFO_1000786 | M16 | — | 1 | 1 | 3 | — | 4 |
| Knee osteoarthritis | D020370 | EFO_0004616 | M17 | — | 1 | 2 | 1 | 1 | 4 |
| Local anesthesia | D000772 | — | — | — | 2 | 1 | 1 | — | 4 |
| Nerve block | D009407 | — | — | — | — | — | 1 | 2 | 3 |
| Spinal anesthesia | D000775 | — | — | — | — | — | 2 | 1 | 3 |
| Hand injuries | D006230 | — | — | — | — | — | 2 | 1 | 3 |
Show 21 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Rupture | D012421 | — | — | — | — | 1 | — | 1 | 2 |
| Job syndrome | D007589 | EFO_0003775 | D82.4 | — | — | 1 | — | — | 1 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | — | — | 1 | — | — | 1 |
| Wounds and injuries | D014947 | — | T14.8 | — | — | 1 | — | — | 1 |
| Emergencies | D004630 | — | — | — | — | 1 | — | — | 1 |
| Analgesia | D000698 | — | — | — | — | 1 | — | — | 1 |
| Vaginal discharge | D019522 | — | — | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Low back pain | D017116 | HP_0003419 | M54.5 | 1 | 1 | — | — | 3 | 4 |
| Peri-implantitis | D057873 | EFO_1001390 | — | — | 1 | — | — | — | 1 |
| Periodontal diseases | D010510 | — | K05.6 | — | 1 | — | — | — | 1 |
| Intervertebral disc degeneration | D055959 | HP_0008419 | — | 1 | 1 | — | — | — | 1 |
| Ischemic stroke | D000083242 | — | — | — | 1 | — | — | — | 1 |
| Anosmia | D000086582 | — | — | 1 | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Compartment syndromes | D003161 | — | T79.A0 | 1 | — | — | — | — | 1 |
| Healthy volunteers/patients | — | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Anterior cruciate ligament injuries | D000070598 | — | — | — | — | — | — | 2 | 2 |
| Bursitis | D002062 | EFO_1000941 | M71.9 | — | — | — | — | 2 | 2 |
| Tooth extraction | D014081 | — | — | — | — | — | — | 2 | 2 |
| Complex regional pain syndromes | D020918 | EFO_1001998 | — | — | — | — | — | 2 | 2 |
| Pancreatitis | D010195 | HP_0001733 | K85 | — | — | — | — | 1 | 1 |
| Cluster headache | D003027 | HP_0012199 | G44.00 | — | — | — | — | 1 | 1 |
| Hypotension | D007022 | EFO_0005251 | I95 | — | — | — | — | 1 | 1 |
| Orthodontic anchorage procedures | D052280 | — | — | — | — | — | — | 1 | 1 |
| Edentulous jaw | D007575 | — | — | — | — | — | — | 1 | 1 |
| Horner syndrome | D006732 | — | G90.2 | — | — | — | — | 1 | 1 |
Show 26 more
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
| Drug common name | Mepivacaine |
| INN | mepivacaine |
| Description | Mepivacaine is a piperidinecarboxamide in which N-methylpipecolic acid and 2,6-dimethylaniline have combined to form the amide bond. It is used as a local amide-type anaesthetic. It has a role as a local anaesthetic and a drug allergen. |
| Classification | Small molecule |
| Drug class | local anesthetics |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | Cc1cccc(C)c1NC(=O)C1CCCCN1C |
Identifiers
| PDB | — |
| CAS-ID | 96-88-8 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1087 |
| ChEBI ID | 6759 |
| PubChem CID | 4062 |
| DrugBank | DB00961 |
| UNII ID | B6E06QE59J (ChemIDplus, GSRS) |
Target
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Subscribe for the real data
Additional graphs summarizing 3,589 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
Subscribe for the real data
928 adverse events reported
View more details
© 2020-2024 Collaborative Drug Discovery Inc. (CDD) | Terms of Use