Mepivacaine
Carbocaine, Polocaine, Polocaine-mpf, Scandonest (mepivacaine) is a small molecule pharmaceutical. Mepivacaine was first approved as Carbocaine w/ neo-cobefrin on 1982-01-01. It is used to treat pain in the USA.
Download report
Favorite
Events Timeline
Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
Mock data
Subscribe for the real data
Subscribe for the real data
Commercial
Therapeutic Areas
Trade Name
FDA
EMA
Polocaine, Polocaine-mpf, Scandonest (discontinued: Arestocaine, Carbocaine, Isocaine, Mepivacaine, Polocaine)
Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
Mepivacaine hydrochloride
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| CARBOCAINE | Eastman Kodak | N-012125 DISCN | 1982-01-01 | 1 products, RLD |
| CARBOCAINE | Hospira | N-012250 DISCN | 1982-01-01 | 3 products, RLD |
Hide discontinued
Levonordefrin
+
Mepivacaine hydrochloride
Tradename | Company | Number | Date | Products |
|---|---|---|---|---|
| CARBOCAINE W/ NEO-COBEFRIN | Eastman Kodak | N-012125 DISCN | 1982-01-01 | 1 products |
Hide discontinued
Labels
FDA
EMA
Brand Name | Status | Last Update |
|---|---|---|
| carbocaine | ANDA | 2024-02-21 |
| isocaine isocaine with levonordefrin | 2007-03-30 | |
| mepivacaine | ANDA | 2024-02-21 |
| mepivacaine hydrochloride | ANDA | 2024-02-21 |
| mepivacaine hydrochloride mepivacaine hydrochloride with levonordefrin | ANDA | 2017-11-23 |
| mepivacaine mepivacaine | ANDA | 2012-05-11 |
| polocaine | ANDA | 2024-02-21 |
| polocaine polocaine-mpf | ANDA | 2022-10-01 |
| polocaine (mepivacaine hcl) | ANDA | 2024-01-30 |
| polocaine polocaine-mpf | ANDA | 2012-09-28 |
Show 2 more
Indications
FDA
EMA
Indication | Ontology | MeSH | ICD-10 |
|---|---|---|---|
| pain | EFO_0003843 | D010146 | R52 |
| toothache | — | D014098 | K08.89 |
| oral ulcer | — | D019226 | — |
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
HCPCS
Code | Description |
|---|---|
| J0670 | Injection, mepivacaine hydrochloride, per 10 ml |
Clinical
Clinical Trials
165 clinical trials
View more details
Mock data
Subscribe for the real data
Subscribe for the real data
Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Anesthesia | D000758 | — | — | — | — | — | 5 | 10 | 15 |
| Pain | D010146 | EFO_0003843 | R52 | — | — | 2 | 6 | 7 | 15 |
| Postoperative pain | D010149 | — | G89.18 | — | — | 2 | 2 | 11 | 15 |
| Local anesthesia | D000772 | — | — | — | 2 | 2 | 3 | 3 | 10 |
| Pulpitis | D011671 | EFO_1001139 | K04.0 | — | 1 | 1 | 3 | 5 | 9 |
| Knee osteoarthritis | D020370 | EFO_0004616 | M17 | — | 1 | 2 | 2 | 3 | 7 |
| Replacement arthroplasty knee | D019645 | — | — | 1 | 1 | — | 4 | 2 | 7 |
| Agnosia | D000377 | EFO_0007136 | F88 | — | — | — | 1 | 5 | 6 |
| Nerve block | D009407 | — | — | — | — | — | 1 | 4 | 5 |
| Hip osteoarthritis | D015207 | EFO_1000786 | M16 | — | 1 | 1 | 3 | — | 4 |
Show 42 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Rupture | D012421 | — | — | — | — | 1 | — | 2 | 3 |
| Forearm injuries | D005543 | — | S59.91 | — | — | 1 | — | 1 | 2 |
| Wrist fractures | D000092503 | — | S52.54 | — | — | 1 | — | 1 | 2 |
| Intervertebral disc degeneration | D055959 | — | — | 1 | 1 | 1 | — | — | 2 |
| Analgesia | D000698 | — | — | — | — | 1 | — | 1 | 2 |
| Radiculopathy | D011843 | — | M54.1 | — | — | 1 | — | 1 | 2 |
| Job syndrome | D007589 | EFO_0003775 | D82.4 | — | — | 1 | — | — | 1 |
| Breast neoplasms | D001943 | EFO_0003869 | C50 | — | — | 1 | — | — | 1 |
| Emergencies | D004630 | — | — | — | — | 1 | — | — | 1 |
| Lacerations | D022125 | — | — | — | — | 1 | — | — | 1 |
Show 4 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Low back pain | D017116 | — | M54.5 | 1 | 1 | — | — | 3 | 4 |
| Knee injuries | D007718 | — | — | — | 1 | — | — | 1 | 2 |
| Chronic periodontitis | D055113 | EFO_0006343 | K05.3 | — | 1 | — | — | 1 | 2 |
| Covid-19 | D000086382 | — | U07.1 | 1 | 2 | — | — | — | 2 |
| Olfaction disorders | D000857 | — | R43.0 | 1 | 2 | — | — | — | 2 |
| Anosmia | D000086582 | — | — | 1 | 2 | — | — | — | 2 |
| Peri-implantitis | D057873 | EFO_1001390 | — | — | 1 | — | — | — | 1 |
| Periodontal diseases | D010510 | — | K05.6 | — | 1 | — | — | — | 1 |
| Back pain | D001416 | — | M54 | 1 | 1 | — | — | — | 1 |
| Spinal diseases | D013122 | — | M45-M49 | 1 | 1 | — | — | — | 1 |
Show 18 more
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Syndrome | D013577 | — | — | 1 | — | — | — | 3 | 4 |
| Healthy volunteers/patients | — | — | — | 2 | — | — | — | — | 2 |
| Compartment syndromes | D003161 | — | T79.A0 | 1 | — | — | — | — | 1 |
| Acute pain | D059787 | — | R52 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Bursitis | D002062 | EFO_1000941 | M71.9 | — | — | — | — | 3 | 3 |
| Ganglion cysts | D045888 | — | M67.4 | — | — | — | — | 3 | 3 |
| Anterior cruciate ligament injuries | D000070598 | — | — | — | — | — | — | 2 | 2 |
| Bone fractures | D050723 | EFO_0003931 | T14.8 | — | — | — | — | 2 | 2 |
| Tooth extraction | D014081 | — | — | — | — | — | — | 2 | 2 |
| Neuralgia | D009437 | EFO_0009430 | — | — | — | — | — | 2 | 2 |
| Postherpetic neuralgia | D051474 | — | — | — | — | — | — | 2 | 2 |
| Complex regional pain syndromes | D020918 | EFO_1001998 | — | — | — | — | — | 2 | 2 |
| Reflex sympathetic dystrophy | D012019 | EFO_1001147 | G90.5 | — | — | — | — | 2 | 2 |
| Shoulder pain | D020069 | — | M25.51 | — | — | — | — | 2 | 2 |
Show 78 more
Epidemiology
Epidemiological information for investigational and approved indications
View more details
Drug
General
| Drug common name | Mepivacaine |
| INN | mepivacaine |
| Description | Mepivacaine is a piperidinecarboxamide in which N-methylpipecolic acid and 2,6-dimethylaniline have combined to form the amide bond. It is used as a local amide-type anaesthetic. It has a role as a local anaesthetic and a drug allergen. |
| Classification | Small molecule |
| Drug class | local anesthetics |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | Cc1cccc(C)c1NC(=O)C1CCCCN1C |
Identifiers
| PDB | — |
| CAS-ID | 96-88-8 |
| RxCUI | — |
| ChEMBL ID | CHEMBL1087 |
| ChEBI ID | 6759 |
| PubChem CID | 4062 |
| DrugBank | DB00961 |
| UNII ID | B6E06QE59J (ChemIDplus, GSRS) |
Target
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
Mock data
Subscribe for the real data
Subscribe for the real data
Additional graphs summarizing 4,733 documents
View more details
Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
Mock data
Subscribe for the real data
Subscribe for the real data
1,286 adverse events reported
View more details
© 2020-2025 Collaborative Drug Discovery Inc. (CDD) | Terms of Use