Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Osteoporosis | D010024 | HP_0000939 | M81.0 | — | 1 | 3 | 2 | 3 | 8 |
Hemorrhage | D006470 | MP_0001914 | R58 | — | — | 1 | 2 | 4 | 7 |
Vascular calcification | D061205 | — | — | — | 1 | 1 | 1 | — | 2 |
Cardiac surgical procedures | D006348 | — | — | — | — | — | 1 | — | 1 |
Prediabetic state | D011236 | EFO_1001121 | R73.03 | — | — | — | 1 | — | 1 |
Diabetes mellitus | D003920 | HP_0000819 | E08-E13 | — | — | — | 1 | — | 1 |
Calcinosis | D002114 | — | — | — | — | — | 1 | — | 1 |
Burns | D002056 | — | T30.0 | — | — | — | 1 | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Thrombosis | D013927 | — | — | 1 | 3 | 2 | — | 1 | 7 |
Atrial fibrillation | D001281 | EFO_0000275 | I48.0 | — | 3 | 1 | — | 1 | 5 |
Venous thrombosis | D020246 | HP_0004936 | I82.40 | 1 | 2 | 2 | — | — | 5 |
Venous thromboembolism | D054556 | EFO_0004286 | I74 | — | 1 | 1 | — | 2 | 4 |
Thromboembolism | D013923 | HP_0001907 | — | — | 1 | 1 | — | 2 | 4 |
Neoplasms | D009369 | — | C80 | 1 | — | 1 | — | — | 2 |
Chronic kidney failure | D007676 | EFO_0003884 | N18.9 | — | 2 | 1 | — | — | 2 |
Postmenopausal osteoporosis | D015663 | EFO_0003854 | — | — | 1 | 2 | — | — | 2 |
Multiple sclerosis | D009103 | EFO_0003885 | G35 | — | — | 1 | — | — | 1 |
Relapsing-remitting multiple sclerosis | D020529 | EFO_0003929 | — | — | — | 1 | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Healthy volunteers/patients | — | — | — | 1 | 1 | — | — | 5 | 7 |
Knee osteoarthritis | D020370 | EFO_0004616 | M17 | 1 | 1 | — | — | — | 1 |
Osteoarthritis | D010003 | EFO_0002506 | M15-M19 | 1 | 1 | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Stroke | D020521 | EFO_0000712 | I63.9 | 1 | — | — | — | — | 1 |
Hypersensitivity | D006967 | HP_0012393 | T78.40 | 1 | — | — | — | — | 1 |
Psoriasis | D011565 | EFO_0000676 | L40 | 1 | — | — | — | — | 1 |
Sickle cell anemia | D000755 | EFO_0000697 | D57 | 1 | — | — | — | — | 1 |
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
---|---|---|---|---|---|---|---|---|---|
Vitamin k deficiency | D014813 | — | E56.1 | — | — | — | — | 3 | 3 |
Drug-related side effects and adverse reactions | D064420 | — | T88.7 | — | — | — | — | 1 | 1 |
Heart valve diseases | D006349 | EFO_0009551 | I08 | — | — | — | — | 1 | 1 |
Metabolic bone diseases | D001851 | HP_0000938 | — | — | — | — | — | 1 | 1 |
Medication adherence | D055118 | EFO_0006344 | — | — | — | — | — | 1 | 1 |
Micronutrients | D018977 | — | — | — | — | — | — | 1 | 1 |
Hypertension | D006973 | EFO_0000537 | I10 | — | — | — | — | 1 | 1 |
Hyperhomocysteinemia | D020138 | — | — | — | — | — | — | 1 | 1 |
Intracranial hemorrhages | D020300 | EFO_0000551 | I62 | — | — | — | — | 1 | 1 |
Traumatic intracranial hemorrhage | D020198 | — | — | — | — | — | — | 1 | 1 |
Drug common name | Menatetrenone |
INN | menatetrenone |
Description | Menaquinone-4 is a menaquinone whose side-chain contains 4 isoprene units in an all-trans-configuration. It has a role as a bone density conservation agent, a human metabolite, an antioxidant, an anti-inflammatory agent and a neuroprotective agent. |
Classification | Small molecule |
Drug class | aldosterone antagonists (spironolactone type) |
Image (chem structure or protein) | |
Structure (InChI/SMILES or Protein Sequence) | CC(C)=CCC/C(C)=C/CC/C(C)=C/CC/C(C)=C/CC1=C(C)C(=O)c2ccccc2C1=O |
PDB | — |
CAS-ID | 863-61-6 |
RxCUI | — |
ChEMBL ID | CHEMBL259223 |
ChEBI ID | 78277 |
PubChem CID | 5282367 |
DrugBank | DB12148 |
UNII ID | 27Y876D139 (ChemIDplus, GSRS) |