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Drug ReportsMenatetrenone
Menatetrenone
Menatetrenone is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
Clinical
Drug
Target
Variants
Financial
Trends
Safety
Events Timeline
5D
1M
3M
6M
YTD
1Y
2Y
5Y
Max
Events
FDA approval date
EMA approval date
Patent expiration date
Study first post date
Last update post date
Start date
Primary completion date
Completion date
Results first post date
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Commercial
Therapeutic Areas
No data
Trade Name
FDA
EMA
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Drug Products
FDA
EMA
New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
Abbreviated New Drug Application (ANDA)
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Labels
FDA
EMA
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Indications
FDA
EMA
No data
Agency Specific
FDA
EMA
No data
Patent Expiration
No data
ATC Codes
M: Musculo-skeletal system drugs
M05: Drugs for treatment of bone diseases
M05B: Drugs affecting bone structure and mineralization
M05BX: Other drugs affecting bone structure and mineralization in atc
M05BX08: Menatetrenone
HCPCS
No data
Clinical
Clinical Trials
62 clinical trials
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Indications Phases 4
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
OsteoporosisD010024HP_0000939M81.013238
HemorrhageD006470MP_0001914R581236
Vascular calcificationD0612051112
Cardiac surgical proceduresD00634811
Prediabetic stateD011236EFO_1001121R73.0311
Diabetes mellitusD003920HP_0000819E08-E1311
CalcinosisD00211411
BurnsD002056T30.011
Indications Phases 3
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
ThrombosisD01392713217
Atrial fibrillationD001281EFO_0000275I48.03115
Venous thrombosisD020246HP_0004936I82.401225
Venous thromboembolismD054556EFO_0004286I741124
ThromboembolismD013923HP_00019071124
NeoplasmsD009369C80112
Chronic kidney failureD007676EFO_0003884N18.9212
Postmenopausal osteoporosisD015663EFO_0003854122
Multiple sclerosisD009103EFO_0003885G3511
Relapsing-remitting multiple sclerosisD020529EFO_000392911
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Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients1157
Knee osteoarthritisD020370EFO_0004616M17111
OsteoarthritisD010003EFO_0002506M15-M19111
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
StrokeD020521EFO_0000712I63.911
HypersensitivityD006967HP_0012393T78.4011
PsoriasisD011565EFO_0000676L4011
Sickle cell anemiaD000755EFO_0000697D5711
Indications Without Phase
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameMenatetrenone
INNmenatetrenone
Description
Menaquinone-4 is a menaquinone whose side-chain contains 4 isoprene units in an all-trans-configuration. It has a role as a bone density conservation agent, a human metabolite, an antioxidant, an anti-inflammatory agent and a neuroprotective agent.
Classification
Small molecule
Drug classaldosterone antagonists (spironolactone type)
Image (chem structure or protein)Loading
Structure (InChI/SMILES or Protein Sequence)
CC(C)=CCC/C(C)=C/CC/C(C)=C/CC/C(C)=C/CC1=C(C)C(=O)c2ccccc2C1=O
Identifiers
PDB
CAS-ID863-61-6
RxCUI
ChEMBL IDCHEMBL259223
ChEBI ID78277
PubChem CID5282367
DrugBankDB12148
UNII ID27Y876D139 (ChemIDplus, GSRS)
Target
No data
Variants
No data
Financial
No data
Trends
PubMed Central
Top Terms for Disease or Syndrome:
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Additional graphs summarizing 1,081 documents
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Safety
Black-box Warning
No Black-box warning
Adverse Events
Top Adverse Reactions
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42 adverse events reported
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