Melarsoprol
Melarsoprol is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Drug Products
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New Drug Application (NDA)
New Drug Application (NDA)
Abbreviated New Drug Application (ANDA)
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Agency Specific
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Clinical
Clinical Trials
26 clinical trials
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Indications Phases 4
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Multiple myeloma | D009101 | — | C90.0 | 1 | 3 | 1 | — | — | 5 |
| Plasma cell neoplasms | D054219 | — | — | 1 | 3 | 1 | — | — | 5 |
| Immunoglobulin light-chain amyloidosis | D000075363 | — | — | — | — | 1 | — | — | 1 |
| Amyloidosis | D000686 | EFO_1001875 | E85 | — | — | 1 | — | — | 1 |
| African trypanosomiasis | D014353 | — | B56 | — | — | 1 | — | — | 1 |
| Trypanosomiasis | D014352 | DOID_10113 | B57.2 | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neoplasms | D009369 | — | C80 | 6 | 3 | — | — | — | 8 |
| Lymphoma | D008223 | — | C85.9 | 3 | 2 | — | — | — | 3 |
| Hematologic neoplasms | D019337 | — | — | — | 2 | — | — | — | 2 |
| Leukemia | D007938 | — | C95 | 1 | 1 | — | — | — | 2 |
| Myelodysplastic syndromes | D009190 | — | D46 | 1 | 1 | — | — | — | 2 |
| Large b-cell lymphoma diffuse | D016403 | — | C83.3 | 1 | 1 | — | — | — | 1 |
| B-cell lymphoma | D016393 | — | — | 1 | 1 | — | — | — | 1 |
| Oral lichen planus | D017676 | — | — | 1 | 1 | — | — | — | 1 |
| Lichen planus | D008010 | — | L43 | 1 | 1 | — | — | — | 1 |
| Atrophy | D001284 | — | — | 1 | 1 | — | — | — | 1 |
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Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Neuroblastoma | D009447 | EFO_0000621 | — | 1 | — | — | — | — | 1 |
| Retinoblastoma | D012175 | — | — | 1 | — | — | — | — | 1 |
| Ganglioneuroblastoma | D018305 | — | — | 1 | — | — | — | — | 1 |
| Carcinoma | D002277 | — | C80.0 | 1 | — | — | — | — | 1 |
| Non-small-cell lung carcinoma | D002289 | — | — | 1 | — | — | — | — | 1 |
| Lung neoplasms | D008175 | — | C34.90 | 1 | — | — | — | — | 1 |
| Melanoma | D008545 | — | — | 1 | — | — | — | — | 1 |
| Myeloproliferative disorders | D009196 | — | D47.1 | 1 | — | — | — | — | 1 |
| Myelodysplastic-myeloproliferative diseases | D054437 | — | — | 1 | — | — | — | — | 1 |
| Preleukemia | D011289 | — | — | 1 | — | — | — | — | 1 |
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Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Metabolic diseases | D008659 | EFO_0000589 | E88.9 | — | — | — | — | 1 | 1 |
| Metabolic brain diseases | D001928 | — | G93.41 | — | — | — | — | 1 | 1 |
| Gastrointestinal diseases | D005767 | — | — | — | — | — | — | 1 | 1 |
| Physiological stress | D013312 | — | — | — | — | — | — | 1 | 1 |
| Anorexia | D000855 | — | R63.0 | — | — | — | — | 1 | 1 |
| Chronic periodontitis | D055113 | EFO_0006343 | K05.3 | — | — | — | — | 1 | 1 |
| Periodontitis | D010518 | EFO_0000649 | K05.3 | — | — | — | — | 1 | 1 |
| Core stability | D000089944 | — | — | — | — | — | — | 1 | 1 |
| Periodontal diseases | D010510 | — | K05.6 | — | — | — | — | 1 | 1 |
Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Melarsoprol |
| INN | melarsoprol |
| Description | Melarsoprol is a member of triazines. |
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | Nc1nc(N)nc(Nc2ccc([As]3SCC(CO)S3)cc2)n1 |
Identifiers
| PDB | — |
| CAS-ID | 494-79-1 |
| RxCUI | — |
| ChEMBL ID | CHEMBL166 |
| ChEBI ID | 6729 |
| PubChem CID | 10311 |
| DrugBank | — |
| UNII ID | ZF3786Q2E8 (ChemIDplus, GSRS) |
Target
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Trends
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Safety
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