Mecrylate
Mecrylate is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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Clinical
Clinical Trials
162 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Esophageal and gastric varices | D004932 | EFO_0009545 | I85 | 1 | — | 2 | 3 | 14 | 20 |
| Liver cirrhosis | D008103 | EFO_0001422 | K74.0 | — | — | — | 4 | 9 | 13 |
| Surgical wound | D000072836 | — | — | 1 | — | — | 2 | 2 | 5 |
| Pain | D010146 | EFO_0003843 | R52 | — | — | — | 1 | 2 | 3 |
| Surgical wound infection | D013530 | — | — | — | — | — | 2 | 1 | 3 |
| Male circumcision | D002944 | EFO_0003953 | — | — | — | — | 2 | 1 | 3 |
| Periodontal diseases | D010510 | — | K05.6 | — | — | — | 1 | 1 | 2 |
| Wounds and injuries | D014947 | — | T14.8 | — | — | — | 1 | 1 | 2 |
| Tissue adhesives | D014014 | — | — | — | — | — | 1 | 1 | 2 |
| Postoperative pain | D010149 | — | G89.18 | — | — | — | 1 | 1 | 2 |
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Hypospadias | D007021 | EFO_0004209 | Q54 | — | 1 | 1 | — | — | 1 |
| Episiotomy | D004841 | — | — | — | — | 1 | — | — | 1 |
| Contact dermatitis | D003877 | — | L25 | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Inguinal hernia | D006552 | HP_0000023 | K40 | — | 1 | — | — | 8 | 9 |
| Lacerations | D022125 | — | — | — | 1 | — | — | 1 | 2 |
| Female infertility | D007247 | EFO_0008560 | N97 | 1 | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pilonidal sinus | D010864 | HP_0010769 | L05 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Portal hypertension | D006975 | EFO_0000666 | K76.6 | — | — | — | — | 6 | 6 |
| Gingival recession | D005889 | — | K06.0 | — | — | — | — | 5 | 5 |
| Varicose veins | D014648 | HP_0002619 | I83.90 | — | — | — | — | 4 | 4 |
| Venous insufficiency | D014689 | — | — | — | — | — | — | 2 | 2 |
| Hypersplenism | D006971 | EFO_1000975 | D73.1 | — | — | — | — | 2 | 2 |
| Keratitis | D007634 | HP_0000491 | H16 | — | — | — | — | 1 | 1 |
| Central venous catheters | D062905 | — | — | — | — | — | — | 1 | 1 |
| Bone diseases | D001847 | — | M89.9 | — | — | — | — | 1 | 1 |
| Prolapse | D011391 | — | — | — | — | — | — | 1 | 1 |
| Surgical portasystemic shunt | D011170 | — | — | — | — | — | — | 1 | 1 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Mecrylate |
| INN | mecrilate |
| Description | Methyl cyanoacrylate (MCA; also sometimes referred to as α-cyanoacrylate or alpha-cyanoacrylate) is an organic compound that contains several functional groups: a methyl ester, a nitrile, and an alkene. It is a colorless liquid with low viscosity. Its chief use is as the main component of cyanoacrylate glues. It can be encountered under many trade names. Methyl cyanoacrylate is less commonly encountered than ethyl cyanoacrylate.
|
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | C=C(C#N)C(=O)OC |
Identifiers
| PDB | — |
| CAS-ID | 137-05-3 |
| RxCUI | — |
| ChEMBL ID | CHEMBL2106424 |
| ChEBI ID | — |
| PubChem CID | 8711 |
| DrugBank | — |
| UNII ID | WN7979561R (ChemIDplus, GSRS) |
Target
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Variants
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Trends
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Safety
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Adverse Events
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35 adverse events reported
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