Mecrylate
Mecrylate is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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Clinical
Clinical Trials
224 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Esophageal and gastric varices | D004932 | EFO_0009545 | I85 | 1 | — | 5 | 7 | 25 | 38 |
| Hernia | D006547 | — | K40-K46 | — | 1 | — | 1 | 15 | 17 |
| Liver cirrhosis | D008103 | EFO_0001422 | K74.0 | — | — | — | 4 | 11 | 15 |
| Inguinal hernia | D006552 | HP_0000023 | K40 | — | 1 | — | 1 | 13 | 15 |
| Surgical wound | D000072836 | — | — | 3 | — | — | 3 | 8 | 14 |
| Wounds and injuries | D014947 | — | T14.8 | — | 1 | — | 2 | 5 | 8 |
| Postoperative pain | D010149 | — | G89.18 | 1 | — | — | 1 | 6 | 8 |
| Wound healing | D014945 | GO_0042060 | — | 1 | — | — | 1 | 5 | 7 |
| Pain | D010146 | EFO_0003843 | R52 | — | — | — | 1 | 5 | 6 |
| Surgical wound infection | D013530 | — | — | — | — | — | 3 | 3 | 6 |
Show 17 more
Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Fibrosis | D005355 | — | — | — | — | 1 | — | 6 | 7 |
| Cicatrix | D002921 | — | L90.5 | — | — | 1 | — | 5 | 6 |
| Ulcer | D014456 | MPATH_579 | — | — | — | 1 | — | 3 | 4 |
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 1 | 2 | 1 | — | — | 4 |
| Dermatitis | D003872 | — | L30.9 | — | — | 1 | — | 2 | 3 |
| Gastrointestinal hemorrhage | D006471 | — | K92.2 | — | — | 1 | — | 1 | 2 |
| Contact dermatitis | D003877 | — | L25 | — | — | 1 | — | 1 | 2 |
| Pancreatic ductal carcinoma | D021441 | — | — | — | 1 | 1 | — | — | 2 |
| Fistula | D005402 | — | — | — | — | 1 | — | — | 1 |
| Urinary fistula | D014548 | — | N36.0 | — | — | 1 | — | — | 1 |
Show 8 more
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pancreatic fistula | D010185 | — | — | 1 | 2 | — | — | — | 3 |
| Infertility | D007246 | EFO_0000545 | — | 1 | 1 | — | — | 1 | 2 |
| Pancreaticoduodenectomy | D016577 | — | — | 1 | 1 | — | — | — | 2 |
| Anastomotic leak | D057868 | — | — | 1 | 1 | — | — | — | 2 |
| Female infertility | D007247 | EFO_0008560 | N97 | 1 | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Varicose veins | D014648 | — | I83.90 | 1 | — | — | — | 17 | 18 |
| Pilonidal sinus | D010864 | — | L05 | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Gingival recession | D005889 | — | K06.0 | — | — | — | — | 10 | 10 |
| Portal hypertension | D006975 | EFO_0000666 | K76.6 | — | — | — | — | 7 | 7 |
| Wound closure techniques | D058106 | — | — | — | — | — | — | 6 | 6 |
| Venous insufficiency | D014689 | — | — | — | — | — | — | 3 | 3 |
| Prolapse | D011391 | — | — | — | — | — | — | 3 | 3 |
| Hypertension | D006973 | EFO_0000537 | I10 | — | — | — | — | 3 | 3 |
| Knee osteoarthritis | D020370 | EFO_0004616 | M17 | — | — | — | — | 3 | 3 |
| Allergic contact dermatitis | D017449 | — | L23 | — | — | — | — | 3 | 3 |
| Head and neck neoplasms | D006258 | — | — | — | — | — | — | 2 | 2 |
| Analgesia | D000698 | — | — | — | — | — | — | 2 | 2 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Mecrylate |
| INN | mecrilate |
| Description | Methyl cyanoacrylate (MCA; also sometimes referred to as α-cyanoacrylate or alpha-cyanoacrylate) is an organic compound that contains several functional groups: a methyl ester, a nitrile, and an alkene. It is a colorless liquid with low viscosity. Its chief use is as the main component of cyanoacrylate glues. It can be encountered under many trade names. Methyl cyanoacrylate is less commonly encountered than ethyl cyanoacrylate.
|
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | C=C(C#N)C(=O)OC |
Identifiers
| PDB | — |
| CAS-ID | 137-05-3 |
| RxCUI | — |
| ChEMBL ID | CHEMBL2106424 |
| ChEBI ID | — |
| PubChem CID | 8711 |
| DrugBank | — |
| UNII ID | WN7979561R (ChemIDplus, GSRS) |
Target
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Variants
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Trends
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Safety
Black-box Warning
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Adverse Events
Top Adverse Reactions
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35 adverse events reported
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