Mecrylate
Mecrylate is a small molecule pharmaceutical. It is currently being investigated in clinical studies.
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Commercial
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Clinical
Clinical Trials
191 clinical trials
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Indications Phases 4
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Esophageal and gastric varices | D004932 | EFO_0009545 | I85 | 1 | — | 5 | 7 | 25 | 38 |
| Hernia | D006547 | — | K40-K46 | — | 1 | — | 1 | 15 | 17 |
| Liver cirrhosis | D008103 | EFO_0001422 | K74.0 | — | — | — | 4 | 10 | 14 |
| Inguinal hernia | D006552 | HP_0000023 | K40 | — | 1 | — | 1 | 12 | 14 |
| Surgical wound | D000072836 | — | — | 3 | — | — | 3 | 7 | 13 |
| Hemorrhage | D006470 | MP_0001914 | R58 | — | — | 3 | 2 | 2 | 7 |
| Wounds and injuries | D014947 | — | T14.8 | — | — | — | 2 | 5 | 7 |
| Wound healing | D014945 | GO_0042060 | — | — | — | — | 1 | 5 | 6 |
| Pain | D010146 | EFO_0003843 | R52 | — | — | — | 1 | 4 | 5 |
| Postoperative pain | D010149 | — | G89.18 | 1 | — | — | 1 | 3 | 5 |
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Indications Phases 3
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Varicose veins | D014648 | — | I83.90 | 1 | — | 1 | — | 18 | 20 |
| Fistula | D005402 | — | — | 1 | 2 | 2 | — | 1 | 5 |
| Dermatitis | D003872 | — | L30.9 | — | — | 1 | — | 4 | 5 |
| Gastrointestinal hemorrhage | D006471 | — | K92.2 | — | — | 1 | — | 1 | 2 |
| Contact dermatitis | D003877 | — | L25 | — | — | 1 | — | 1 | 2 |
| Urinary fistula | D014548 | — | N36.0 | — | — | 1 | — | — | 1 |
| Hypospadias | D007021 | EFO_0004209 | Q54 | — | 1 | 1 | — | — | 1 |
| Cutaneous fistula | D017577 | — | — | — | 1 | 1 | — | — | 1 |
| Episiotomy | D004841 | — | — | — | — | 1 | — | — | 1 |
| Liver failure | D017093 | — | K72.9 | — | — | 1 | — | — | 1 |
Indications Phases 2
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Infertility | D007246 | EFO_0000545 | — | 1 | 1 | — | — | 1 | 2 |
| Pancreatic neoplasms | D010190 | EFO_0003860 | C25 | 1 | 1 | — | — | — | 2 |
| Pancreatic fistula | D010185 | — | — | 1 | 1 | — | — | — | 2 |
| Female infertility | D007247 | EFO_0008560 | N97 | 1 | 1 | — | — | — | 1 |
| Pancreatic ductal carcinoma | D021441 | — | — | — | 1 | — | — | — | 1 |
Indications Phases 1
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Pilonidal sinus | D010864 | — | L05 | 1 | — | — | — | — | 1 |
| Pancreaticoduodenectomy | D016577 | — | — | 1 | — | — | — | — | 1 |
Indications Without Phase
Indication | MeSH | Ontology | ICD-10 | Ph 1 | Ph 2 | Ph 3 | Ph 4 | Other | Total |
|---|---|---|---|---|---|---|---|---|---|
| Gingival recession | D005889 | — | K06.0 | — | — | — | — | 9 | 9 |
| Fibrosis | D005355 | — | — | — | — | — | — | 6 | 6 |
| Portal hypertension | D006975 | EFO_0000666 | K76.6 | — | — | — | — | 6 | 6 |
| Venous insufficiency | D014689 | — | — | — | — | — | — | 3 | 3 |
| Prolapse | D011391 | — | — | — | — | — | — | 3 | 3 |
| Wound closure techniques | D058106 | — | — | — | — | — | — | 3 | 3 |
| Hypertension | D006973 | EFO_0000537 | I10 | — | — | — | — | 3 | 3 |
| Ulcer | D014456 | MPATH_579 | — | — | — | — | — | 3 | 3 |
| Knee osteoarthritis | D020370 | EFO_0004616 | M17 | — | — | — | — | 3 | 3 |
| Carcinoma | D002277 | — | C80.0 | — | — | — | — | 3 | 3 |
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
| Drug common name | Mecrylate |
| INN | mecrilate |
| Description | Methyl cyanoacrylate (MCA; also sometimes referred to as α-cyanoacrylate or alpha-cyanoacrylate) is an organic compound that contains several functional groups: a methyl ester, a nitrile, and an alkene. It is a colorless liquid with low viscosity. Its chief use is as the main component of cyanoacrylate glues. It can be encountered under many trade names. Methyl cyanoacrylate is less commonly encountered than ethyl cyanoacrylate.
|
| Classification | Small molecule |
| Drug class | — |
| Image (chem structure or protein) |  |
| Structure (InChI/SMILES or Protein Sequence) | C=C(C#N)C(=O)OC |
Identifiers
| PDB | — |
| CAS-ID | 137-05-3 |
| RxCUI | — |
| ChEMBL ID | CHEMBL2106424 |
| ChEBI ID | — |
| PubChem CID | 8711 |
| DrugBank | — |
| UNII ID | WN7979561R (ChemIDplus, GSRS) |
Target
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Variants
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Trends
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Safety
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Adverse Events
Top Adverse Reactions
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35 adverse events reported
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